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The map label for this gene is grx [H]

Identifier: 78067653

GI number: 78067653

Start: 3331694

End: 3331939

Strand: Reverse

Name: grx [H]

Synonym: Bcep18194_A6184

Alternate gene names: 78067653

Gene position: 3331939-3331694 (Counterclockwise)

Preceding gene: 78067654

Following gene: 78067652

Centisome position: 90.2

GC content: 65.04

Gene sequence:

>246_bases
ATGTACAGCACGCAGGTGTGTCCGTATTGCATCCAGGCCGAGCGCCTGCTGAAGCTGCGCGGTGTCGAGCAGATCGAGAA
GGTGCTGATCGACCGCGATCCGGCCCGCCGCGACGAAATGATGACGCGCACGGGGCGCCGCACGGTGCCGCAGATCTATA
TCGGCGACACGCACGTCGGCGGTTACGACGATCTGTCGAAGCTCGACCGCGAAGGCGGGCTCGTACCGCTTCTGCAAGCG
GCCTGA

Upstream 100 bases:

>100_bases
GTTACGCCGAGGTGCACGTGCTCGAGGGCGGCGTGGCCGCCTGGCAGCAGGCCGGGATGCCGGTCGTCAAACAAGGAGTG
GCGAAGTGAACAAGGTTTTG

Downstream 100 bases:

>100_bases
TTAGGGCAGAATGGCCGCCGGCCGCGCCGCGGCTTGGGCGCGCAGGATTCATCCGTGGCGGCCGGCGCGAAGCCGGGCCG
CCCCGTCACCACTTTTAGGG

Product: glutaredoxin GrxC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 81; Mature: 81

Protein sequence:

>81_residues
MYSTQVCPYCIQAERLLKLRGVEQIEKVLIDRDPARRDEMMTRTGRRTVPQIYIGDTHVGGYDDLSKLDREGGLVPLLQA
A

Sequences:

>Translated_81_residues
MYSTQVCPYCIQAERLLKLRGVEQIEKVLIDRDPARRDEMMTRTGRRTVPQIYIGDTHVGGYDDLSKLDREGGLVPLLQA
A
>Mature_81_residues
MYSTQVCPYCIQAERLLKLRGVEQIEKVLIDRDPARRDEMMTRTGRRTVPQIYIGDTHVGGYDDLSKLDREGGLVPLLQA
A

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=79, Percent_Identity=49.3670886075949, Blast_Score=83, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9221; Mature: 9221

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTQVCPYCIQAERLLKLRGVEQIEKVLIDRDPARRDEMMTRTGRRTVPQIYIGDTHVG
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEECCCCCC
GYDDLSKLDREGGLVPLLQAA
CCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MYSTQVCPYCIQAERLLKLRGVEQIEKVLIDRDPARRDEMMTRTGRRTVPQIYIGDTHVG
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEECCCCCC
GYDDLSKLDREGGLVPLLQAA
CCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]