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The map label for this gene is ilvE [H]

Identifier: 78067431

GI number: 78067431

Start: 3092241

End: 3093164

Strand: Direct

Name: ilvE [H]

Synonym: Bcep18194_A5962

Alternate gene names: 78067431

Gene position: 3092241-3093164 (Clockwise)

Preceding gene: 78067421

Following gene: 78067432

Centisome position: 83.71

GC content: 64.72

Gene sequence:

>924_bases
ATGTCAATGGCCGACCGCGACGGCAAGATCTGGATGGACGGCAAGCTGATCGACTGGCGCGACGCCAAGATCCACGTCCT
GACCCACACGCTGCACTACGGCATGGGCGTCTTCGAGGGCGTGCGCGCGTACAAGTCGGCCGACGGCAGCACCGCGATCT
TCCGCCTGTACGAGCACACGAAACGTCTGCTGAATTCGGCGAAGATCTTCCAGATGGACGTGCCGTTCGACCGGGAAACG
CTCGAAGCCGCGCAGCTCGAAGTCGTGCGCGAGAACAAGCTCGAGTCGTGCTACCTGCGCCCGATCATCTGGGTCGGCTC
GGAAAAGCTCGGCGTGGCCGCGAAGGGCAACACGATCCACGTCGCGATCGCCGCTTGGCCGTGGGGCGCGTACCTCGGCG
AGGAAGGCCTCGCGAAGGGCATCCGCGTGAAGACGTCGTCGTTCACGCGCCACCACGTGAACGTGTCGATGGTGCGCGCG
AAGGCGTCGGGCTGGTACGTGAACTCGATCCTGGCGAACCAGGAAGCGACGGCCGACGGCTACGACGAAGCGCTGCTGCT
CGACGTCGACGGCTACGTGTCGGAAGGCTCTGGCGAGAACTTCTTCCTGGTGAACAACGGCAAGCTGTACACGCCCGACC
TGTCGTCGTGCCTCGACGGCATCACGCGCGATACCGTCATCACGCTCGCGAAGGACGCCGGCATCGAGGTGATCGAGAAG
CGCATCACGCGCGACGAGGTCTACACGGCCGACGAGGCGTTCTTCACCGGCACGGCCGCTGAAGTCACGCCGATCCGCGA
GCTCGACAACCGCACGATCGGCAGCGGCGCGCGCGGCCCCGTCACGGAAAAGCTCCAGTCGGCGTTTTTCGATATCGTGT
CGGGCAAGAACGCGAAGTACGCGCACTGGCTGACGAAGGTCTGA

Upstream 100 bases:

>100_bases
CGCCGGCCCCGCGCCGACCGACCGGATCGCCTTCAAATGACGCTAAAATAAGCGTCTTTCCGGCTCAACGCTGCATACAA
CCGCATCCCAGGAGAAATCT

Downstream 100 bases:

>100_bases
GCGCGCCGCGCCACCGACCGCCCCACAAAAGAGTGATAAGAGAAAGTCTCATGAGTGAAATCAAGGAAATGCCGCTGGTC
GAGCTGACGGCCAAGGATCT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSMADRDGKIWMDGKLIDWRDAKIHVLTHTLHYGMGVFEGVRAYKSADGSTAIFRLYEHTKRLLNSAKIFQMDVPFDRET
LEAAQLEVVRENKLESCYLRPIIWVGSEKLGVAAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRA
KASGWYVNSILANQEATADGYDEALLLDVDGYVSEGSGENFFLVNNGKLYTPDLSSCLDGITRDTVITLAKDAGIEVIEK
RITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGSGARGPVTEKLQSAFFDIVSGKNAKYAHWLTKV

Sequences:

>Translated_307_residues
MSMADRDGKIWMDGKLIDWRDAKIHVLTHTLHYGMGVFEGVRAYKSADGSTAIFRLYEHTKRLLNSAKIFQMDVPFDRET
LEAAQLEVVRENKLESCYLRPIIWVGSEKLGVAAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRA
KASGWYVNSILANQEATADGYDEALLLDVDGYVSEGSGENFFLVNNGKLYTPDLSSCLDGITRDTVITLAKDAGIEVIEK
RITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGSGARGPVTEKLQSAFFDIVSGKNAKYAHWLTKV
>Mature_306_residues
SMADRDGKIWMDGKLIDWRDAKIHVLTHTLHYGMGVFEGVRAYKSADGSTAIFRLYEHTKRLLNSAKIFQMDVPFDRETL
EAAQLEVVRENKLESCYLRPIIWVGSEKLGVAAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAK
ASGWYVNSILANQEATADGYDEALLLDVDGYVSEGSGENFFLVNNGKLYTPDLSSCLDGITRDTVITLAKDAGIEVIEKR
ITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGSGARGPVTEKLQSAFFDIVSGKNAKYAHWLTKV

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=334, Percent_Identity=26.9461077844311, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI48994963, Length=300, Percent_Identity=47.6666666666667, Blast_Score=282, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17565728, Length=282, Percent_Identity=26.241134751773, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322608, Length=285, Percent_Identity=25.2631578947368, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322002, Length=305, Percent_Identity=26.8852459016393, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641779, Length=319, Percent_Identity=26.0188087774295, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34016; Mature: 33885

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMADRDGKIWMDGKLIDWRDAKIHVLTHTLHYGMGVFEGVRAYKSADGSTAIFRLYEHT
CCCCCCCCEEEECCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KRLLNSAKIFQMDVPFDRETLEAAQLEVVRENKLESCYLRPIIWVGSEKLGVAAKGNTIH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECEEEEECCCCEEEEECCCEEE
VAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADG
EEEEECCCHHHHCCHHHHCCEEEEECCCEEEEEEEEEEEEECCCEEEEHHHCCCCCCCCC
YDEALLLDVDGYVSEGSGENFFLVNNGKLYTPDLSSCLDGITRDTVITLAKDAGIEVIEK
CCCEEEEEECCCEECCCCCEEEEEECCEEECCCHHHHHCCCCCCCEEEEECCCCHHHHHH
RITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGSGARGPVTEKLQSAFFDIVSGKNAKY
HHHHHHHEECCCCEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
AHWLTKV
HHHEECC
>Mature Secondary Structure 
SMADRDGKIWMDGKLIDWRDAKIHVLTHTLHYGMGVFEGVRAYKSADGSTAIFRLYEHT
CCCCCCCEEEECCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KRLLNSAKIFQMDVPFDRETLEAAQLEVVRENKLESCYLRPIIWVGSEKLGVAAKGNTIH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECEEEEECCCCEEEEECCCEEE
VAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADG
EEEEECCCHHHHCCHHHHCCEEEEECCCEEEEEEEEEEEEECCCEEEEHHHCCCCCCCCC
YDEALLLDVDGYVSEGSGENFFLVNNGKLYTPDLSSCLDGITRDTVITLAKDAGIEVIEK
CCCEEEEEECCCEECCCCCEEEEEECCEEECCCHHHHHCCCCCCCEEEEECCCCHHHHHH
RITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGSGARGPVTEKLQSAFFDIVSGKNAKY
HHHHHHHEECCCCEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
AHWLTKV
HHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]