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The map label for this gene is degP [H]

Identifier: 78067416

GI number: 78067416

Start: 3074444

End: 3075928

Strand: Reverse

Name: degP [H]

Synonym: Bcep18194_A5947

Alternate gene names: 78067416

Gene position: 3075928-3074444 (Counterclockwise)

Preceding gene: 78067417

Following gene: 78067415

Centisome position: 83.27

GC content: 68.22

Gene sequence:

>1485_bases
ATGAACACCCGATTCCTTGCGCGCGGCGCCGTCGCGGTCGCCGTGGCGGCCGCCCTGTCCGCCGGCTATGTCGCCGGCAC
CCGCCGCGCCGATCCGCAGATCATCACGCCCGCACAGGCGGCGGCGCTGATGCCGGCCGAAGCGGCCGCGAAGACCGGCA
TCCCCGATTTCTCCGGGCTCGTCGAGACCTACGGCCCGGCGGTCGTGAACATCAGCGCGAAGCACGTCGTGAAGCAGGTG
TCGCGGCGCGTGCCGCAGCCGCAACTGCCGATCGATCCGAGCGATCCGTTCTACCAGTTCTTCAAGCACTTCTACGGCCA
GGTGCCGGGCATGGGCGGTGACGCGCAGCCGGACGACCAGCCGAGCGCGAGCCTCGGTTCCGGGTTCGTCATCAGCTCCG
ACGGGTACATCCTCACCAATGCGCACGTGATCGACGGCGCGAACGTCGTCACGGTCAAGCTGACCGACAAGCGCGAATAC
AAGGCGAAGGTCGTCGGCTCCGACAAGCAGTCCGACGTCGCGGTGCTGAAGATCGACGCAAGCGGCCTGCCGACCGTGAA
GATCGGCGACCCGGCGCAGAGCAAGGTCGGCCAGTGGGTCGTCGCGATCGGTTCGCCGTACGGCTTCGACAACACGGTCA
CGTCGGGCATCATCAGCGCGAAGTCGCGTGCGCTGCCGGACGAGAACTACACGCCGTTCATCCAGACCGACGTGCCGGTG
AACCCCGGCAACTCGGGCGGCCCGCTGTTCAACCTGCAGGGTGAGGTGATCGGCATCAACTCGATGATCTACTCGCAGAC
GGGCGGCTTCCAGGGCCTGTCGTTCGCGATCCCGATCAACGAGGCGATCAAGGTGAAGGACGAACTCGTGAAGACGGGCC
ACGTGAGCCGCGGCCGCCTCGGCGTCGCCGTGCAGGGGCTGAACCAGACGCTCGCGAGCTCGTTCGGACTGCAGAAGCCG
GACGGCGCGCTCGTCAGCTCGGTCGATCCGAACGGCCCGGCCGCGAAGGCCGGCCTGCAGCCGGGTGACGTGATCCTGTC
GGTCAACGGCTCGCCGGTTGCCGATTCGACGTCGCTGCCCGCGCAGATCGCGAACCTGAAGCCGGGTTCGAAGGCCGACC
TGCAGATCTGGCGCGACAAGTCGAAGAAGTCGATCAGCGTGACGCTCGGCGCGATGGCCGACGCGAAGCTCGCGTCGAAC
GACGGCGGCCCTGTTGAACAAGGGCGCCTGGGCGTCGCGGTGCGTCCGCTGTCGCCGCAGGAGCGCAGTGCCGACAACCT
GTCGCACGGCCTGATCGTGCAGCAGGCCGGCGGGCCGGCCGCGAACGCGGGCATCCAGCCCGGCGACGTGATCCTCGCGG
TCAACGGCCGCCCGGTCACGAGCCCCGAGCAGTTGCGCGACGCGGTCAAGGGCGCGGGCAACAGTCTTGCTCTGCTGATC
CAGCGCGATAATGCACAGATCTTCGTGCCGGTCGACCTGAGCTGA

Upstream 100 bases:

>100_bases
GAACGCCGCCGGGCGGCCGCTTAAGCCCCGCTTAAGGCTGATTAAGCCTCCTTTAAGTCAGGGTCGTTACGCTGCGTCCT
AACAAAGAGGAGGTCCTACG

Downstream 100 bases:

>100_bases
CCGGCCACGGCCGACGGCCGGCCAGGCCGGCCGCAGCGGGCGCCGCCGCCGTGCTGAATGGGTGACGCAGCGCCCTGTAT
GTGTTCCGACCCCAAGGAGA

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MNTRFLARGAVAVAVAAALSAGYVAGTRRADPQIITPAQAAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKQV
SRRVPQPQLPIDPSDPFYQFFKHFYGQVPGMGGDAQPDDQPSASLGSGFVISSDGYILTNAHVIDGANVVTVKLTDKREY
KAKVVGSDKQSDVAVLKIDASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVPV
NPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRLGVAVQGLNQTLASSFGLQKP
DGALVSSVDPNGPAAKAGLQPGDVILSVNGSPVADSTSLPAQIANLKPGSKADLQIWRDKSKKSISVTLGAMADAKLASN
DGGPVEQGRLGVAVRPLSPQERSADNLSHGLIVQQAGGPAANAGIQPGDVILAVNGRPVTSPEQLRDAVKGAGNSLALLI
QRDNAQIFVPVDLS

Sequences:

>Translated_494_residues
MNTRFLARGAVAVAVAAALSAGYVAGTRRADPQIITPAQAAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKQV
SRRVPQPQLPIDPSDPFYQFFKHFYGQVPGMGGDAQPDDQPSASLGSGFVISSDGYILTNAHVIDGANVVTVKLTDKREY
KAKVVGSDKQSDVAVLKIDASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVPV
NPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRLGVAVQGLNQTLASSFGLQKP
DGALVSSVDPNGPAAKAGLQPGDVILSVNGSPVADSTSLPAQIANLKPGSKADLQIWRDKSKKSISVTLGAMADAKLASN
DGGPVEQGRLGVAVRPLSPQERSADNLSHGLIVQQAGGPAANAGIQPGDVILAVNGRPVTSPEQLRDAVKGAGNSLALLI
QRDNAQIFVPVDLS
>Mature_494_residues
MNTRFLARGAVAVAVAAALSAGYVAGTRRADPQIITPAQAAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKQV
SRRVPQPQLPIDPSDPFYQFFKHFYGQVPGMGGDAQPDDQPSASLGSGFVISSDGYILTNAHVIDGANVVTVKLTDKREY
KAKVVGSDKQSDVAVLKIDASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVPV
NPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRLGVAVQGLNQTLASSFGLQKP
DGALVSSVDPNGPAAKAGLQPGDVILSVNGSPVADSTSLPAQIANLKPGSKADLQIWRDKSKKSISVTLGAMADAKLASN
DGGPVEQGRLGVAVRPLSPQERSADNLSHGLIVQQAGGPAANAGIQPGDVILAVNGRPVTSPEQLRDAVKGAGNSLALLI
QRDNAQIFVPVDLS

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=249, Percent_Identity=38.9558232931727, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI22129776, Length=265, Percent_Identity=36.9811320754717, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI7019477, Length=281, Percent_Identity=36.2989323843416, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI24308541, Length=253, Percent_Identity=35.1778656126482, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1786356, Length=482, Percent_Identity=35.4771784232365, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789629, Length=491, Percent_Identity=35.030549898167, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=39.8523985239852, Blast_Score=192, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24646839, Length=296, Percent_Identity=35.1351351351351, Blast_Score=151, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 50963; Mature: 50963

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRFLARGAVAVAVAAALSAGYVAGTRRADPQIITPAQAAALMPAEAAAKTGIPDFSGL
CCCCEEECCHHHHHHHHHHHCCCEECCCCCCCCEECCHHHHHHCCHHHHHHCCCCCHHHH
VETYGPAVVNISAKHVVKQVSRRVPQPQLPIDPSDPFYQFFKHFYGQVPGMGGDAQPDDQ
HHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
PSASLGSGFVISSDGYILTNAHVIDGANVVTVKLTDKREYKAKVVGSDKQSDVAVLKIDA
CCCCCCCCEEEECCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEECC
SGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVPV
CCCCEEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCC
NPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRL
CCCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEE
GVAVQGLNQTLASSFGLQKPDGALVSSVDPNGPAAKAGLQPGDVILSVNGSPVADSTSLP
EEEEECHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCC
AQIANLKPGSKADLQIWRDKSKKSISVTLGAMADAKLASNDGGPVEQGRLGVAVRPLSPQ
HHHHCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCC
ERSADNLSHGLIVQQAGGPAANAGIQPGDVILAVNGRPVTSPEQLRDAVKGAGNSLALLI
CCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEE
QRDNAQIFVPVDLS
EECCCEEEEEEECC
>Mature Secondary Structure
MNTRFLARGAVAVAVAAALSAGYVAGTRRADPQIITPAQAAALMPAEAAAKTGIPDFSGL
CCCCEEECCHHHHHHHHHHHCCCEECCCCCCCCEECCHHHHHHCCHHHHHHCCCCCHHHH
VETYGPAVVNISAKHVVKQVSRRVPQPQLPIDPSDPFYQFFKHFYGQVPGMGGDAQPDDQ
HHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
PSASLGSGFVISSDGYILTNAHVIDGANVVTVKLTDKREYKAKVVGSDKQSDVAVLKIDA
CCCCCCCCEEEECCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEECC
SGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVPV
CCCCEEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCC
NPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRL
CCCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEE
GVAVQGLNQTLASSFGLQKPDGALVSSVDPNGPAAKAGLQPGDVILSVNGSPVADSTSLP
EEEEECHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCC
AQIANLKPGSKADLQIWRDKSKKSISVTLGAMADAKLASNDGGPVEQGRLGVAVRPLSPQ
HHHHCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCC
ERSADNLSHGLIVQQAGGPAANAGIQPGDVILAVNGRPVTSPEQLRDAVKGAGNSLALLI
CCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEE
QRDNAQIFVPVDLS
EECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]