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The map label for this gene is rssA [H]

Identifier: 78067417

GI number: 78067417

Start: 3076030

End: 3077376

Strand: Reverse

Name: rssA [H]

Synonym: Bcep18194_A5948

Alternate gene names: 78067417

Gene position: 3077376-3076030 (Counterclockwise)

Preceding gene: 78067418

Following gene: 78067416

Centisome position: 83.3

GC content: 71.79

Gene sequence:

>1347_bases
GTGAGGTCGATTCGTCATCAATTGCTGATCTGGCTGCTCGCGATCGTCGTCGCGGGCGTGGGCATCGCGGGCTGGCTCAT
CTACCGGCAGGCGCTCGCCGAAGCGAACGAACTGTTCGACTACCAGTTGCAGGAAATCGCCGCGGCCTTGCCGTCGGAGC
CGTTCTCGCAGGTGTTCGGCTCGCGCACCAACGGCGACGAAGGCATCGTGATCCAGATCTGGAACCGCAACGGCGTGCTG
ATGTACTTCTCGCATCCGCGTGCGCCGATCGCGCCGCGCGCGGAGCTCGGCTTCTCGACCGAGCGCACCGATCGCGGCGA
ATGGCGCGTGTACGGCGCGATCGTCGGCGACAACGTCGTGCAGCTCGCGCAGCCGCTGTCGGTGCGCAACCGGCTCGCGG
CGAACGTCGCGCTGCGCACGCTGTGGCCGCTGATCGTGCTGCTGCCGTTCCTCGGCGCGGCCGTGTGGGTGATCGTCGGG
CGCGGGCTCGCGCCGCTCGGCCGCGTGACGCGCGCGGTCGAGGCGCGCCGGCCGGAAGCGCTCGATCCGCTGCCCGATGC
GCGCCTGCCGCTCGAGGTGCAGCCGCTCGTACGGGCGCTGAACGGGCTGCTCGCGCGGCTGGCGGCCGCGCTCGACACGC
AAAAGGCCTTCGTGGCCGACGCCGCGCACGAACTGCGTACGCCGCTCGCGGCCGTGCAGATCCAGGCGCAGCTCGTCGCC
CGCGCGAAGGACGACGCATCGCGCCGCGAGGCGGTCGCGGATCTCCAGGATGGCGTGTCGCGAGCGACGCGTCTCACGGA
GCAGCTGCTCGCGCTCGCACGCGCCGAACCGGATGGCGCGACGATGCGCGAGCCGGTCGACCTGCAGGCATTGCTTGCCG
AATGCGTGGCCGCGCTTGCGCCGCTCGCGCAACGGCACGACATCGATCTCGGCTTCGAGGAGACGCGTGCGGCGAGCGTC
GTCGCGGACGTCGGCGCGTTGCGCGTGATGTTCGGCAACCTGCTCGACAACGCGGTGAAGTACACGCCGGACGGCGGCCG
CATCGACGTGTCGCTGACCCGCGACGCGGCCGGTCGCGCATGCGTGCAGATCGGCGACAGCGGGCCCGGCATTCCGGCCG
ACGAGCGCGAGCGCGTGTTCGACCGCTTCTACCGCGACAGCTCCGCGCGGGCGCGCACCGACGTGTCGGGCAGCGGGCTC
GGGCTCGCGATCGTCAAGCGCGTGGCCGCGCAGCAGGGTGCAACGGTGTCGCTCGGCGACGCGGCTGCAGGCGGGCTGCT
CGTCAGCGTCGTGTTCCGCGATGCCGAGATGCCGGCCGAGGCGCCGCAGCCGTCCGAATCCGTGTGA

Upstream 100 bases:

>100_bases
GGTCGAGGTCTACATCCACGCGCTGCGCAAGAAGCTCGGCTCGGACCTGATCCGCAACGTGCGCGGGCTCGGCTACATGG
TCGTCAAGGAAAGCTGACGC

Downstream 100 bases:

>100_bases
AGAACGCCGCCGGGCGGCCGCTTAAGCCCCGCTTAAGGCTGATTAAGCCTCCTTTAAGTCAGGGTCGTTACGCTGCGTCC
TAACAAAGAGGAGGTCCTAC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRSIRHQLLIWLLAIVVAGVGIAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWVIVG
RGLAPLGRVTRAVEARRPEALDPLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDASRREAVADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAALAPLAQRHDIDLGFEETRAASV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIGDSGPGIPADERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAEAPQPSESV

Sequences:

>Translated_448_residues
MRSIRHQLLIWLLAIVVAGVGIAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWVIVG
RGLAPLGRVTRAVEARRPEALDPLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDASRREAVADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAALAPLAQRHDIDLGFEETRAASV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIGDSGPGIPADERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAEAPQPSESV
>Mature_448_residues
MRSIRHQLLIWLLAIVVAGVGIAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWVIVG
RGLAPLGRVTRAVEARRPEALDPLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDASRREAVADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAALAPLAQRHDIDLGFEETRAASV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIGDSGPGIPADERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAEAPQPSESV

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=457, Percent_Identity=30.4157549234136, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788279, Length=317, Percent_Identity=27.1293375394322, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786783, Length=347, Percent_Identity=26.8011527377522, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=31.8897637795276, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787374, Length=292, Percent_Identity=28.7671232876712, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790551, Length=257, Percent_Identity=33.0739299610895, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=32.1070234113712, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=27.5109170305677, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789808, Length=240, Percent_Identity=29.1666666666667, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=28.8702928870293, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI48994928, Length=215, Percent_Identity=24.6511627906977, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082128, Length=257, Percent_Identity=28.4046692607004, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=28.0334728033473, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=214, Percent_Identity=26.6355140186916, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=25.8426966292135, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=212, Percent_Identity=26.8867924528302, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=209, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI145693157, Length=220, Percent_Identity=25.9090909090909, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48028; Mature: 48028

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIRHQLLIWLLAIVVAGVGIAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
SRTNGDEGIVIQIWNRNGVLMYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVV
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWVIVGRGLAPLGRVTRAVEARRPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
LDPLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RAKDDASRREAVADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
PLAQRHDIDLGFEETRAASVVADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCE
CVQIGDSGPGIPADERERVFDRFYRDSSARARTDVSGSGLGLAIVKRVAAQQGATVSLGD
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCC
AAAGGLLVSVVFRDAEMPAEAPQPSESV
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSIRHQLLIWLLAIVVAGVGIAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
SRTNGDEGIVIQIWNRNGVLMYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVV
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWVIVGRGLAPLGRVTRAVEARRPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
LDPLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RAKDDASRREAVADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
PLAQRHDIDLGFEETRAASVVADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCE
CVQIGDSGPGIPADERERVFDRFYRDSSARARTDVSGSGLGLAIVKRVAAQQGATVSLGD
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCC
AAAGGLLVSVVFRDAEMPAEAPQPSESV
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA