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The map label for this gene is ygfU [H]

Identifier: 78067406

GI number: 78067406

Start: 3061794

End: 3063170

Strand: Direct

Name: ygfU [H]

Synonym: Bcep18194_A5937

Alternate gene names: 78067406

Gene position: 3061794-3063170 (Clockwise)

Preceding gene: 78067402

Following gene: 78067410

Centisome position: 82.88

GC content: 65.5

Gene sequence:

>1377_bases
ATGCAATCGAACACGGTCCATCCGTGCGATGAAGTGCTGCCGACCGGCAAGCTGGTAACGCTTGGCCTGCAACACGTCCT
CGTCATGTACGCCGGCGCTGTCGCCGTGCCGCTTATCGTCGGCGCCGCGCTCAAGCTGCCGAAAGACCAGATCGCGTTTC
TGATCAGCGCCGATCTGTTTTCGTGCGGCATCGCCACGCTGATCCAGACGCTCGGCCTGTGGGTCTTCGGGATCCGCCTG
CCCGTCATCATGGGCTGCACGTTCGCGGCAGTCGGCCCGATGATCGCGATCGGCACCAACCCCGGCCTCGGCATCCTCGA
CATCTTCGGCTCGACCATCGCGGCCGGCATCATCGGCATCGTGCTGGCGCCGATGATCGGCAAGCTGTTGCGGTTCTTCC
CGCCAGTGGTCGTCGGCACCGTGATCGCGGTGATCGGGCTGTCGCTGATGGAAGTCGGCATCAACTGGGCGGCCGGCGGC
GTCGGCAATCCCGAGTACGGCAGCCCCGTCTATCTCGGCCTGTCGCTGCTCGTGCTGACACTGATCCTGCTGATCAACAA
GTACGGCCGCGGCTTCATCGCGAACATCTCGGTGCTGCTCGGCATCGTCGCCGGCTTCGCGATCGCCTTCGCGATCGGCC
GCGTGAATACCGACGGCGTCGCGCACGCACCGTGGGTCGGCTTCGTGATGCCGTTCCACTTCGGCCTGCCGCACTTCGAC
CCGCTGTCGATCGTGACGATGGTCACGGTGATGTTCGTCACGTTCATCGAATCGACCGGCATGTTCCTCGCGGTTGGCGA
CATGGTCGATCGCCCGGTCAACCAGGAGCGCCTCGTGCGCGGCCTGCGCGTCGACGGCCTCGGCACGCTGATCGGCGGCA
TCTTCAACTCGTTCCCGCATACGTCGTTCTCGCAGAACGTCGGCCTGATCGGCGTGACGGGCGTGAAGAGCCGGTTCGTG
TGCGCCACCGGCGGCGTGATCCTCGTGCTGCTCGGCCTGTTCCCGAAGATGGCGCAGGTCGTCGCATCGGTGCCGCCGTT
CGTGCTCGGCGGTGCGGGCATCGTGATGTTCGGGATGGTGGCGGCGAACGGCATCAAGGTGCTGTCGAAGGTCGACTTCG
TGAACAACACGCACAACCTGTTCATCGTCGCCGTGAGCGTCGGCATGGGCCTCGTGCCGGTCGTGTCGCCGCACTTCTTC
TCGAAGCTGCCGCCCGCGCTCGCCCCGATCCTGCACAGCGGCATCCTGCTGGCATCGGCGACGGCCGTGATCCTGAACAT
CGTGTTCAACGGCGTGAAAGGCGAGAAGGATGCGCGCTGCGACATCCGCCGCGCCGGACATGACTTCGACGGGCGTCCCG
CCGACGTGCATCACTGA

Upstream 100 bases:

>100_bases
GAACCAGCAAAGAACGGAATAGTACCCAGCACTCTTGTTGCGTGGATTCATTCCGAATAATTTCGTATCACCCCGAAAAC
AAGATCATGGAGTGAGACAG

Downstream 100 bases:

>100_bases
TCGCCACGCGCCGGACGACGGCGCGAAGAAGCGGTAACGAAAACGCCACGGCATGCCGTGGCGTTTTGCTTTGGGGAGGC
TGGATGGTGCGCGATGATCG

Product: xanthine/uracil transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGAALKLPKDQIAFLISADLFSCGIATLIQTLGLWVFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVIAVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKYGRGFIANISVLLGIVAGFAIAFAIGRVNTDGVAHAPWVGFVMPFHFGLPHFD
PLSIVTMVTVMFVTFIESTGMFLAVGDMVDRPVNQERLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVNNTHNLFIVAVSVGMGLVPVVSPHFF
SKLPPALAPILHSGILLASATAVILNIVFNGVKGEKDARCDIRRAGHDFDGRPADVHH

Sequences:

>Translated_458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGAALKLPKDQIAFLISADLFSCGIATLIQTLGLWVFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVIAVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKYGRGFIANISVLLGIVAGFAIAFAIGRVNTDGVAHAPWVGFVMPFHFGLPHFD
PLSIVTMVTVMFVTFIESTGMFLAVGDMVDRPVNQERLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVNNTHNLFIVAVSVGMGLVPVVSPHFF
SKLPPALAPILHSGILLASATAVILNIVFNGVKGEKDARCDIRRAGHDFDGRPADVHH
>Mature_458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGAALKLPKDQIAFLISADLFSCGIATLIQTLGLWVFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVIAVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKYGRGFIANISVLLGIVAGFAIAFAIGRVNTDGVAHAPWVGFVMPFHFGLPHFD
PLSIVTMVTVMFVTFIESTGMFLAVGDMVDRPVNQERLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVNNTHNLFIVAVSVGMGLVPVVSPHFF
SKLPPALAPILHSGILLASATAVILNIVFNGVKGEKDARCDIRRAGHDFDGRPADVHH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=517, Percent_Identity=26.3056092843327, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI40316845, Length=517, Percent_Identity=26.3056092843327, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI44680145, Length=485, Percent_Identity=25.7731958762887, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI44680143, Length=489, Percent_Identity=25.5623721881391, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI222080105, Length=469, Percent_Identity=23.6673773987207, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI222080107, Length=477, Percent_Identity=23.2704402515723, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082181, Length=437, Percent_Identity=59.2677345537757, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1790087, Length=443, Percent_Identity=30.6997742663657, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI87082178, Length=457, Percent_Identity=29.3216630196937, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1788843, Length=384, Percent_Identity=28.6458333333333, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87081818, Length=409, Percent_Identity=29.8288508557457, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17558856, Length=504, Percent_Identity=25.5952380952381, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17541904, Length=464, Percent_Identity=22.8448275862069, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=453, Percent_Identity=25.3863134657837, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17542260, Length=197, Percent_Identity=26.9035532994924, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=197, Percent_Identity=27.4111675126904, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356175, Length=439, Percent_Identity=24.6013667425968, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47807; Mature: 47807

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]