| Definition | Burkholderia sp. 383 chromosome 1, complete genome. |
|---|---|
| Accession | NC_007510 |
| Length | 3,694,126 |
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The map label for this gene is icd [H]
Identifier: 78067324
GI number: 78067324
Start: 2972226
End: 2974454
Strand: Reverse
Name: icd [H]
Synonym: Bcep18194_A5855
Alternate gene names: 78067324
Gene position: 2974454-2972226 (Counterclockwise)
Preceding gene: 78067325
Following gene: 78067322
Centisome position: 80.52
GC content: 65.68
Gene sequence:
>2229_bases ATGTCCACTTCGCCCAAGATCATCTACACCCTCACTGACGAAGCGCCCGCGCTCGCGACCTATTCGCTGCTGCCGATCGT CAAGGCCTTCACGCGCTCGTCCGGCGTCGCCGTCGAAACGCGCGACATCTCGCTCGCCGGCCGCATCATCGCGGCATTCG CAGACGTCCTGCAGCCCGAGCAGAAGGGTTCCGACGATCTGGCCGAACTGGGCCAGCTCACGCTGAAGCCGGAAGCGAAC ATCATCAAGCTGCCGAACATCAGCGCATCGGTGCCGCAGCTGAAGGCCGCGATCGCCGAACTGCAGGCGCAGGGCTTCCA GCTGCCGGCCTATCCGGAAGATCCGTCGACGGACGAAGAGAAGGCGGTCAAGGCCCGCTACGACAAGATCAAGGGCAGCG CGGTGAACCCGGTGCTGCGCGAAGGCAACTCCGACCGCCGCGCGCCGCTGTCGGTCAAGAATTACGCACGCAAGCATCCG CACAAGATGGGCGCGTGGAAGGCCACGTCGAAGGCGCACGTTGCGCACATGAGCGAAGGCGACTTCTACGGCAGCGAGAA GTCGGTGCTGATCGCCGATGCCGGCAGCGTGAAGATCGAACTCACGACGGCCGACGGCGCGAAGAAGGTACTGAAGGAAA AGACGGCCGTGAAGGCCGGTGAAGTGATCGACGCATCGGTGATGAGCCGCAATGCGCTGCGCAGCTTCATCGACGCGCAG ATCGCGGATGCGAAGGCCCAGGACGTGCTGTTCTCGGTGCACCTGAAGGCGACCATGATGAAGGTCTCGGACCCGATCCT GTTCGGCCACTTCGTGTCGGTGTTCTACCGCGATGTGCTCGCGAAGCACGCTGACGTGCTGGCGCAGGTCGGCTTCAACC CGAACAACGGGATCGGCGACCTGTACGCACGCCTGAAGGACCTGCCGGCCGATACGCGCGAAGCGATCGAAGCCGACGTC AAGGCGGAATACGCCGTGCGTCCGCGCCTGGCGATGGTCAACTCGGACAAGGGCATCACGAACCTGCACGTGCCGAGCGA CGTGATCGTCGACGCATCGATGCCGGCGATGATCCGCGACTCGGGCGGCATGTGGGGCCCGGACGGCCAGCTGTACGACG CGAAGGCCGTGATTCCGGACCGTTGCTACGCAGGTGTCTACCAGGCCGTGATCGAGGACTGCAAGCAGCATGGCGCGTTC GATCCGGTCACGATGGGCAGCGTGCCGAACGTCGGCCTGATGGCGCAGGCGGCTGAAGAATACGGTTCGCACGACAAGAC GTTCCAGATCCCGGCAGACGGCGTCGTGCGCGTCACCGACGAAGCGGGCAACGTGCTGCTCGAGCATGCAGTGGAAGCGG GCGACATCTGGCGCATGTGCCAGACGAAGGACGCACCGGTGCAGGACTGGGTCAAGCTCGCGGTCAACCGCGCACGCGCG ACCGGCGCACCGGCCGTGTTCTGGCTCGATCCGGCGCGCGCGCACGACGCGCAGATCATCGCGAAGGTCGAGCGTTACCT GAAGGATCACGACACGAACGGCCTCGACATCCGCGTGATGACGCCGGTCGACGCGACGCGTTTCTCGCTCGAGCGCATCC GTGCGGGCAAGGACACGATCTCGGTCACCGGCAACGTCCTGCGCGACTACCTGACCGACCTGTTCCCGATCATGGAACTC GGCACCAGCGCGAAGATGCTGTCGATCGTGCCGCTGATGGCCGGCGGCGGGATGTTCGAAACGGGTGCGGGCGGTTCGGC GCCGAAGCACGTGCAGCAGTTCGTCGAGGAAGGCTTCCTGCGCTGGGATTCGCTCGGCGAATTCCTCGCGCTGGCCGCGT CGCTCGAACACCTTGGCAATGCCTACCAGAACCCGAAGGCGGTCGTGCTCGCGAAGACGCTCGACCAGGCGACCGGCAAG TTCCTGGACGAGAACAAGTCGCCGGCGCGCAAGGTCGGCGGCCTCGACAACCGCGGCAGCCACTTCTACCTGTGCCTGTA CTGGGCGCAGGCGCTGGCCGAGCAGACCGAGGACGCAGCGCTGAAGGCGCAGTTCGAAGGTGTGGCGAAGGCGCTGTCCG ACAGCGAAGCGCGCATCCTGGAAGAACTGGCGGCCGCGCAGGGCAAGGCGCAGGCGATCGGCGGCTACTACCGTCCGAAC GTTGACCTGACGAGCCAGGCCATGCGCCCGAGCGCGACGCTGAACGGCATCGTCGACGCGGTCGCCTGA
Upstream 100 bases:
>100_bases GGCTGAGCCGGCGTGCCCCTTTCGCGACCGACCCGGTCGCTCCCCGCCGGTTACCCGCCGGCGTTCTCAGTCCAAATTTT CACGTAGCAACGCATCGACC
Downstream 100 bases:
>100_bases CGCAGGCCGCGCGATCGCGCGGGCCGATGCGTGTGCCAGTGCGGCGGGCATTGCTGCCTGCCGCCGGCTACAAAAGAAAA ACGCCCCGGACGCCCGGGGC
Product: isocitrate dehydrogenase (NADP+)
Products: NA
Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]
Number of amino acids: Translated: 742; Mature: 741
Protein sequence:
>742_residues MSTSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLQPEQKGSDDLAELGQLTLKPEAN IIKLPNISASVPQLKAAIAELQAQGFQLPAYPEDPSTDEEKAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHP HKMGAWKATSKAHVAHMSEGDFYGSEKSVLIADAGSVKIELTTADGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIDAQ IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDVLAKHADVLAQVGFNPNNGIGDLYARLKDLPADTREAIEADV KAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAF DPVTMGSVPNVGLMAQAAEEYGSHDKTFQIPADGVVRVTDEAGNVLLEHAVEAGDIWRMCQTKDAPVQDWVKLAVNRARA TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRVMTPVDATRFSLERIRAGKDTISVTGNVLRDYLTDLFPIMEL GTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFLRWDSLGEFLALAASLEHLGNAYQNPKAVVLAKTLDQATGK FLDENKSPARKVGGLDNRGSHFYLCLYWAQALAEQTEDAALKAQFEGVAKALSDSEARILEELAAAQGKAQAIGGYYRPN VDLTSQAMRPSATLNGIVDAVA
Sequences:
>Translated_742_residues MSTSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLQPEQKGSDDLAELGQLTLKPEAN IIKLPNISASVPQLKAAIAELQAQGFQLPAYPEDPSTDEEKAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHP HKMGAWKATSKAHVAHMSEGDFYGSEKSVLIADAGSVKIELTTADGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIDAQ IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDVLAKHADVLAQVGFNPNNGIGDLYARLKDLPADTREAIEADV KAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAF DPVTMGSVPNVGLMAQAAEEYGSHDKTFQIPADGVVRVTDEAGNVLLEHAVEAGDIWRMCQTKDAPVQDWVKLAVNRARA TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRVMTPVDATRFSLERIRAGKDTISVTGNVLRDYLTDLFPIMEL GTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFLRWDSLGEFLALAASLEHLGNAYQNPKAVVLAKTLDQATGK FLDENKSPARKVGGLDNRGSHFYLCLYWAQALAEQTEDAALKAQFEGVAKALSDSEARILEELAAAQGKAQAIGGYYRPN VDLTSQAMRPSATLNGIVDAVA >Mature_741_residues STSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLQPEQKGSDDLAELGQLTLKPEANI IKLPNISASVPQLKAAIAELQAQGFQLPAYPEDPSTDEEKAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPH KMGAWKATSKAHVAHMSEGDFYGSEKSVLIADAGSVKIELTTADGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIDAQI ADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDVLAKHADVLAQVGFNPNNGIGDLYARLKDLPADTREAIEADVK AEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAFD PVTMGSVPNVGLMAQAAEEYGSHDKTFQIPADGVVRVTDEAGNVLLEHAVEAGDIWRMCQTKDAPVQDWVKLAVNRARAT GAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRVMTPVDATRFSLERIRAGKDTISVTGNVLRDYLTDLFPIMELG TSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFLRWDSLGEFLALAASLEHLGNAYQNPKAVVLAKTLDQATGKF LDENKSPARKVGGLDNRGSHFYLCLYWAQALAEQTEDAALKAQFEGVAKALSDSEARILEELAAAQGKAQAIGGYYRPNV DLTSQAMRPSATLNGIVDAVA
Specific function: Unknown
COG id: COG2838
COG function: function code C; Monomeric isocitrate dehydrogenase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the monomeric-type IDH family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001804 - InterPro: IPR004436 [H]
Pfam domain/function: PF03971 IDH [H]
EC number: =1.1.1.42 [H]
Molecular weight: Translated: 79952; Mature: 79821
Theoretical pI: Translated: 6.01; Mature: 6.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLQPE CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCC QKGSDDLAELGQLTLKPEANIIKLPNISASVPQLKAAIAELQAQGFQLPAYPEDPSTDEE CCCCHHHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH KAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWKATSKAHVAHMSEG HHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHEEECCCC DFYGSEKSVLIADAGSVKIELTTADGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIDAQ CCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDVLAKHADVLAQVGFNPNNGIGD HHCCHHHHHEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH LYARLKDLPADTREAIEADVKAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRD HHHHHHHCCCCHHHHHHHHCCHHHEECCEEEEEECCCCCEEEECCCCEEECCCCCCCEEC SGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAFDPVTMGSVPNVGLMAQAAEE CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHH YGSHDKTFQIPADGVVRVTDEAGNVLLEHAVEAGDIWRMCQTKDAPVQDWVKLAVNRARA HCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRVMTPVDATRFSLERIRAGKDTI CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEE SVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFL EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH RWDSLGEFLALAASLEHLGNAYQNPKAVVLAKTLDQATGKFLDENKSPARKVGGLDNRGS HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC HFYLCLYWAQALAEQTEDAALKAQFEGVAKALSDSEARILEELAAAQGKAQAIGGYYRPN EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCEECCC VDLTSQAMRPSATLNGIVDAVA CCCHHHHCCCCHHHHHHHHHCC >Mature Secondary Structure STSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLQPE CCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCC QKGSDDLAELGQLTLKPEANIIKLPNISASVPQLKAAIAELQAQGFQLPAYPEDPSTDEE CCCCHHHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH KAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWKATSKAHVAHMSEG HHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHEEECCCC DFYGSEKSVLIADAGSVKIELTTADGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIDAQ CCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDVLAKHADVLAQVGFNPNNGIGD HHCCHHHHHEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH LYARLKDLPADTREAIEADVKAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRD HHHHHHHCCCCHHHHHHHHCCHHHEECCEEEEEECCCCCEEEECCCCEEECCCCCCCEEC SGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAFDPVTMGSVPNVGLMAQAAEE CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHH YGSHDKTFQIPADGVVRVTDEAGNVLLEHAVEAGDIWRMCQTKDAPVQDWVKLAVNRARA HCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRVMTPVDATRFSLERIRAGKDTI CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEE SVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFL EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH RWDSLGEFLALAASLEHLGNAYQNPKAVVLAKTLDQATGKFLDENKSPARKVGGLDNRGS HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC HFYLCLYWAQALAEQTEDAALKAQFEGVAKALSDSEARILEELAAAQGKAQAIGGYYRPN EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCEECCC VDLTSQAMRPSATLNGIVDAVA CCCHHHHCCCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12005040; 4149369; 12467571 [H]