Click here to switch to the map view.

The map label for this gene is nadA [H]

Identifier: 78067307

GI number: 78067307

Start: 2951155

End: 2952291

Strand: Reverse

Name: nadA [H]

Synonym: Bcep18194_A5838

Alternate gene names: 78067307

Gene position: 2952291-2951155 (Counterclockwise)

Preceding gene: 78067308

Following gene: 78067306

Centisome position: 79.92

GC content: 64.56

Gene sequence:

>1137_bases
ATGCAATCGACGATCAAACCCGTCGAGTACGACCGGCCCGTTGCAGCAGGGACCGTGTGCGGCGTGGGGCAGGCCTGGGC
CAAGGTGCCCGATGCACCGTCCGCCGAAGAGCGGGCCGCGCTGAAGGAGCGCATCAAGGCATTGCTCGTGCGTGAAAAGG
CCGTACTGGTCGCACACTACTACGTCGATGCCGAATTGCAGGAACTCGCCGACGAAACCGGCGGCTGTGTCGCCGATTCG
CTCGAAATGGCCCGCTTCGGCCGTGACCACGACGCGCAGACGCTGATCGTCGCCGGCGTGCGCTTCATGGGCGAAACCGC
GAAGATCCTGAGCCCGAACAAACGAATCCTGATGCCCGATCTCGACGCGACCTGCTCGCTCGACCTCGGCTGCCCGGTCG
ACGAATTCTCGGCGTTCTGCGATGCGCATCCGGACCGCACCGTCGTCGTCTACGCGAATACCAGCGCTGCCGTGAAGGCG
CGTGCGGACTGGATGGTCACGTCGTCGATCGGCCTCGAGATCGTGGCCGACCTGCATGCGCGCGGCGAGAAGATCATCTG
GGCACCGGATCGCCATCTCGGTAGCTACATCCAGAAGAAAACCGGCGCGGACATGCTGCTGTGGCAAGGCTCGTGTCTCG
TCCACGACGAATTCAAGGGCATCGAGCTCGACCTGCTGCGCGCCGAGTATCCGGACGCGAAGGTGCTCGTCCACCCCGAA
TCGCCGGAAAACGTCGTCGCGCAGGCCGATGTGGTCGGCTCGACCACGCAACTGATCGACGCGGCGGTCAAGTTCAACGC
GACGCACTTCATCGTCGCGACCGATCTCGGCATCCTGCACAAGATGCAGCTTGCGGCACCGGGCAAGACCTTCATTGCCG
CGCCGACGGCCGGCAACAGCGCCACCTGCAAGAGCTGCGCGCACTGCCCGTGGATGGCGATGAACGGCCTCGCGAACCTC
GCTGACGTGCTCGAACGCGGTCACAACGAGATCTTCGTCGATCCCGCGATCGGCGAGCGCGCACGCCTGCCGATCGACCG
GATGCTCGATTTCGCAGCCGCGCACAAGAAGCGCGTGCAGGCGAGCGGTGATCTGCAACGCGATCAGCAATTGTTTGCGA
ACGTGGGGGCTGCATGA

Upstream 100 bases:

>100_bases
GGATCGGGGTTGGCGCTAAAGCGCTGGCGCTGATCGACCGCGAAGCATGGGGTGGGAGTAAGTGCTAAAGCACTCACTCC
CGCCGACAGGAGATATGGAG

Downstream 100 bases:

>100_bases
CGAACTCCGCAGTATCCCCGCTGTTCAGCAGCGTCCGCGAGCAATACGGCGCGGCATTCGACGATGCGATCGCACGCAAC
GTGGCCGATGCAATCGCGGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKERIKALLVREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
SPENVVAQADVVGSTTQLIDAAVKFNATHFIVATDLGILHKMQLAAPGKTFIAAPTAGNSATCKSCAHCPWMAMNGLANL
ADVLERGHNEIFVDPAIGERARLPIDRMLDFAAAHKKRVQASGDLQRDQQLFANVGAA

Sequences:

>Translated_378_residues
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKERIKALLVREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
SPENVVAQADVVGSTTQLIDAAVKFNATHFIVATDLGILHKMQLAAPGKTFIAAPTAGNSATCKSCAHCPWMAMNGLANL
ADVLERGHNEIFVDPAIGERARLPIDRMLDFAAAHKKRVQASGDLQRDQQLFANVGAA
>Mature_378_residues
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKERIKALLVREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
SPENVVAQADVVGSTTQLIDAAVKFNATHFIVATDLGILHKMQLAAPGKTFIAAPTAGNSATCKSCAHCPWMAMNGLANL
ADVLERGHNEIFVDPAIGERARLPIDRMLDFAAAHKKRVQASGDLQRDQQLFANVGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=65.3374233128834, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40818; Mature: 40818

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKERIKALLVREKAVLVAHY
CCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEE
YVDAELQELADETGGCVADSLEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPD
EECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEECC
LDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVADLHA
CCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCCEEEEHHHC
RGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
CCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCC
SPENVVAQADVVGSTTQLIDAAVKFNATHFIVATDLGILHKMQLAAPGKTFIAAPTAGNS
CCCCCEEEHHHCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCC
ATCKSCAHCPWMAMNGLANLADVLERGHNEIFVDPAIGERARLPIDRMLDFAAAHKKRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
ASGDLQRDQQLFANVGAA
CCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKERIKALLVREKAVLVAHY
CCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEE
YVDAELQELADETGGCVADSLEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPD
EECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEECC
LDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVADLHA
CCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCCEEEEHHHC
RGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
CCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCC
SPENVVAQADVVGSTTQLIDAAVKFNATHFIVATDLGILHKMQLAAPGKTFIAAPTAGNS
CCCCCEEEHHHCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCC
ATCKSCAHCPWMAMNGLANLADVLERGHNEIFVDPAIGERARLPIDRMLDFAAAHKKRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
ASGDLQRDQQLFANVGAA
CCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA