Click here to switch to the map view.

The map label for this gene is sir1 [H]

Identifier: 78067275

GI number: 78067275

Start: 2919356

End: 2921035

Strand: Reverse

Name: sir1 [H]

Synonym: Bcep18194_A5806

Alternate gene names: 78067275

Gene position: 2921035-2919356 (Counterclockwise)

Preceding gene: 78067279

Following gene: 78067274

Centisome position: 79.07

GC content: 64.82

Gene sequence:

>1680_bases
ATGTATCAGTACGACCAATACGACCAGACGATCGTCGATGAGCGTGTCGCGCAGTACCGCGATCAGGTGCGCCGCCGGCT
GTCGGGCGAGTTGAGCGAAGAAGAGTTCCGTCCGCTGCGCCTGCAGAACGGCCTGTACATGCAGCGCCACGCGTACATGC
ACCGCATCGCGATTCCTTACGGCAACCTGCGGAGCGACCAGCTCCGGATGCTGGCGCGCATCGCCCGCGAACACGACCGC
GGCTACGGTCACTTCTCGACCCGCTCGAACATCCAGTTCAACTGGATCGAGCTGGAAGATACGCCCGAGATCCTCGCGAA
GCTCGCGTCGGTGCAGATGCACGGCATCCAGACGTCGGGCAACTGCATCCGCAACATCACGGCCGACCAGTTCGCCGGTG
TCGCGCAGGACGAAGAGATCGATCCGCGTCCGTGGTCGGAAATCCTGCGTCAGTGGTCGACGTTCCATCCCGAATTCGCA
TGGCTGCCGCGCAAGTTCAAGATCGCGGTGTCGGGCTCGAAGGACGACCGCGCGGCCGTGCAGATCCACGACCTCGGCGT
GTACCTGAAGAAGAACGCGCAGGGCGAAGTGGTCGCGAGCATCCTCGCGGGCGGCGGCCTCGGCCGTACGCCGATCATCG
GCGCGGTGATCAAGGAAGACCTGCCGTGGCAGCACCTGCTCACCTACTGCGAAGCCGTGCTGCGCGTGTACAACCGTTAC
GGCCGCCGCGACAACCTGTACAAGGCGCGTATCAAGATCCTCGTGAAGGCGCTGTCGCCCGCGAAGTTCGCGCAGCAGGT
CGAGGAAGAGTGGCAGCACCTGAAGGACGGCCCGTCGACGCTCACGCAGGCGGAAGTCGATCGCGTGTCGCAATACTTCC
AGCCGCCCGTCTACGAGAAGCTGGCCGACACCGACGCATCGTTCGAACAGCACCTGCTCGAGAACAAGGCGTTCGCGCGC
TGGGTCGAGCGTAACGTTGCACCGCACAAGGTGGCCGGCTATGCAGCCGTCACGCTGTCGCTGAAGGATCACCGGGTCGC
GCCGGGCGATGCGACCGACCAGCAGATGGAGCTGGTGGCCGACTGGGCCGACGCGTACTCGTTCGGCGAGCTGCGCGTGT
CGCACGAGCAGAACCTGATTCTCGCGAACGTGAAGAAGCGCGACCTGTTCGCGGTGTGGGAAAAGGCGAAGGCAGCCGGT
TTCGCGACGCCGAACATCGGCCTGCTGACCGACATCATCGCGTGCCCGGGCGGCGACTTCTGCTCGCTCGCGAACGCGAA
GTCGATCCCGATCGCGCTGGCAATCCAGCAGCGTTTCGACGATCTCGACTATGTGTACGACCTCGGCGACCTGTCGCTGA
ACATTTCCGGTTGCATGAACTCGTGCGGTCACCACCACGTCGGCAACATCGGCATCCTCGGCGTCGACAAGGACGGCGCC
GAGTGGTACCAGGTGTCGCTCGGCGGCGAGCAGGGCACGGGCCAGAACGGCGCGCGCCTCGGCCGCGTGATCGGGCCGTC
GTTCTCGGCGGAAGAAGTGCCCGACGTGATCGCGAAGCTGATCGACACGTTCGTCGAGTCGCGCGTCGACGGCGAGCGCT
TCGTCGAAACGTACGATCGCATCGGCATCGCGCCGTTCAAGGAGCGCGTGTATGCGGCGCGCCAGGCAGTGAACGCGTAA

Upstream 100 bases:

>100_bases
CCACCCGGCAGCGGATGGGGGCGGTGACGGCGGAACGGAGATTCGGGCGCGACGTGGCTAGGACGTCGCGCGGTCACCAC
GAAAACCCTGGGGTCCCCGA

Downstream 100 bases:

>100_bases
CCAACCGGGTAGAAGGAATTAGCAGATGGCTTCGATTATCAAGAACCGCGCAGTGATCGACGATGCATGGCAGGTCGTGC
GCGCGGCAGAAGACGGTGCA

Product: sulfite reductase (NADPH) beta subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEEEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSDQLRMLARIAREHDR
GYGHFSTRSNIQFNWIELEDTPEILAKLASVQMHGIQTSGNCIRNITADQFAGVAQDEEIDPRPWSEILRQWSTFHPEFA
WLPRKFKIAVSGSKDDRAAVQIHDLGVYLKKNAQGEVVASILAGGGLGRTPIIGAVIKEDLPWQHLLTYCEAVLRVYNRY
GRRDNLYKARIKILVKALSPAKFAQQVEEEWQHLKDGPSTLTQAEVDRVSQYFQPPVYEKLADTDASFEQHLLENKAFAR
WVERNVAPHKVAGYAAVTLSLKDHRVAPGDATDQQMELVADWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAG
FATPNIGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGDLSLNISGCMNSCGHHHVGNIGILGVDKDGA
EWYQVSLGGEQGTGQNGARLGRVIGPSFSAEEVPDVIAKLIDTFVESRVDGERFVETYDRIGIAPFKERVYAARQAVNA

Sequences:

>Translated_559_residues
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEEEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSDQLRMLARIAREHDR
GYGHFSTRSNIQFNWIELEDTPEILAKLASVQMHGIQTSGNCIRNITADQFAGVAQDEEIDPRPWSEILRQWSTFHPEFA
WLPRKFKIAVSGSKDDRAAVQIHDLGVYLKKNAQGEVVASILAGGGLGRTPIIGAVIKEDLPWQHLLTYCEAVLRVYNRY
GRRDNLYKARIKILVKALSPAKFAQQVEEEWQHLKDGPSTLTQAEVDRVSQYFQPPVYEKLADTDASFEQHLLENKAFAR
WVERNVAPHKVAGYAAVTLSLKDHRVAPGDATDQQMELVADWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAG
FATPNIGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGDLSLNISGCMNSCGHHHVGNIGILGVDKDGA
EWYQVSLGGEQGTGQNGARLGRVIGPSFSAEEVPDVIAKLIDTFVESRVDGERFVETYDRIGIAPFKERVYAARQAVNA
>Mature_559_residues
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEEEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSDQLRMLARIAREHDR
GYGHFSTRSNIQFNWIELEDTPEILAKLASVQMHGIQTSGNCIRNITADQFAGVAQDEEIDPRPWSEILRQWSTFHPEFA
WLPRKFKIAVSGSKDDRAAVQIHDLGVYLKKNAQGEVVASILAGGGLGRTPIIGAVIKEDLPWQHLLTYCEAVLRVYNRY
GRRDNLYKARIKILVKALSPAKFAQQVEEEWQHLKDGPSTLTQAEVDRVSQYFQPPVYEKLADTDASFEQHLLENKAFAR
WVERNVAPHKVAGYAAVTLSLKDHRVAPGDATDQQMELVADWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAG
FATPNIGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGDLSLNISGCMNSCGHHHVGNIGILGVDKDGA
EWYQVSLGGEQGTGQNGARLGRVIGPSFSAEEVPDVIAKLIDTFVESRVDGERFVETYDRIGIAPFKERVYAARQAVNA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 62948; Mature: 62948

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEEEFRPLRLQNGLYMQRHAYMHRIAIPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHHHHHHHHHHEECCC
GNLRSDQLRMLARIAREHDRGYGHFSTRSNIQFNWIELEDTPEILAKLASVQMHGIQTSG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCC
NCIRNITADQFAGVAQDEEIDPRPWSEILRQWSTFHPEFAWLPRKFKIAVSGSKDDRAAV
CHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCEEEEEEECCCCCCEEE
QIHDLGVYLKKNAQGEVVASILAGGGLGRTPIIGAVIKEDLPWQHLLTYCEAVLRVYNRY
EEEECCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GRRDNLYKARIKILVKALSPAKFAQQVEEEWQHLKDGPSTLTQAEVDRVSQYFQPPVYEK
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
LADTDASFEQHLLENKAFARWVERNVAPHKVAGYAAVTLSLKDHRVAPGDATDQQMELVA
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
DWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAGFATPNIGLLTDIIACPGGDF
HHHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
CSLANAKSIPIALAIQQRFDDLDYVYDLGDLSLNISGCMNSCGHHHVGNIGILGVDKDGA
CCCCCCCCCCEEEEEHHHCCCHHHHEECCCCEEEHHHHHHCCCCCCCCCEEEEEECCCCC
EWYQVSLGGEQGTGQNGARLGRVIGPSFSAEEVPDVIAKLIDTFVESRVDGERFVETYDR
CEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGIAPFKERVYAARQAVNA
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEEEFRPLRLQNGLYMQRHAYMHRIAIPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHHHHHHHHHHEECCC
GNLRSDQLRMLARIAREHDRGYGHFSTRSNIQFNWIELEDTPEILAKLASVQMHGIQTSG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCC
NCIRNITADQFAGVAQDEEIDPRPWSEILRQWSTFHPEFAWLPRKFKIAVSGSKDDRAAV
CHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCEEEEEEECCCCCCEEE
QIHDLGVYLKKNAQGEVVASILAGGGLGRTPIIGAVIKEDLPWQHLLTYCEAVLRVYNRY
EEEECCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GRRDNLYKARIKILVKALSPAKFAQQVEEEWQHLKDGPSTLTQAEVDRVSQYFQPPVYEK
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
LADTDASFEQHLLENKAFARWVERNVAPHKVAGYAAVTLSLKDHRVAPGDATDQQMELVA
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
DWADAYSFGELRVSHEQNLILANVKKRDLFAVWEKAKAAGFATPNIGLLTDIIACPGGDF
HHHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
CSLANAKSIPIALAIQQRFDDLDYVYDLGDLSLNISGCMNSCGHHHVGNIGILGVDKDGA
CCCCCCCCCCEEEEEHHHCCCHHHHEECCCCEEEHHHHHHCCCCCCCCCEEEEEECCCCC
EWYQVSLGGEQGTGQNGARLGRVIGPSFSAEEVPDVIAKLIDTFVESRVDGERFVETYDR
CEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGIAPFKERVYAARQAVNA
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA