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The map label for this gene is btuC [H]

Identifier: 78067255

GI number: 78067255

Start: 2900880

End: 2901878

Strand: Reverse

Name: btuC [H]

Synonym: Bcep18194_A5786

Alternate gene names: 78067255

Gene position: 2901878-2900880 (Counterclockwise)

Preceding gene: 78067260

Following gene: 78067254

Centisome position: 78.55

GC content: 72.57

Gene sequence:

>999_bases
ATGAGCGCCGCGCGCGCCACCGCGATCTGGGCCCTGCTGGCTGCAGCGGTCGCGTTGCTGTTCGTCGCGTCACTGTCGAT
CGGCAGCGTGCCGATGTCGCCATGGCAGGCGCTCGCGTCGCTCGTGCCGCATGGCGGCGACGCGCTGTTCGCCGATATCG
TCCGCACGCTGCGCCTGCCGCGCGCGCTCGCGGGCTTCGCATGCGGCGCGCTGCTCGCGCTGGCCGGTGCACTGCTGCAG
GTGCTGCTGCGCAATCCGCTCGCGGAGCCGTACGTGCTCGGCGTGTCGGGTGGCGCAGCCGGCTTTGCGCTCGTCGCGAT
GATCGCGGGCGGCGCGTGGTGGCTCGTCGATGCGTCGGCGTTTGCCGGCTCGCTCGTGTCGGTCGCGCTCGTGCTCGGTC
TTGCGCGCCGCGAGCTGTGGCGCGGCGAATCGCGCGATGCTTCGCCGCGGCTGCTGCTCACGGGCGTCGTGATCGCGGCG
GGGTGGGGCGCGCTCGTCACGCTGCTGCTGTCGCTCGCGCCCGATGCACGATTGCGCGGGATCATCTTCTGGCTGACCGG
CGACCTGAACGGCGTGACCACGCCGTGGTTCGCGTGCGGTGCGCTGTTGCTGGCCGCATGCGTCGCGTTGCCGGCCGCGC
CGCAACTGAACGTGCTGCTGCGCGGCGATGCGACCGCGCTCGCGCTCGGCGTGCCCGTTGCGCGCCTGCGCGTGCGGATC
TATCTCGTCGCATCGCTGGCCGCCGCGGCCGCGGTGACGACGGCCGGCACGATCGGTTTCGTCGGCCTCGTCGTGCCGCA
TGCGCTGCGGCTCGCTTTCGGCAACGACCAGCGGATGCTGCTGCCGGCCGCGATGCTCGCGGGCGGCGGCGGCGTGATGG
CGGCCGACCTGCTCGCACGCACTGCGATCGCGCCCGCGCAACTGCCGGTCGGCGTGATGACCGCATTGATCGGCGTGCCG
GTGTTCCTGTGGATGTTGTTGAGGAGGCCGATGCGATGA

Upstream 100 bases:

>100_bases
CTTCGATGCTGACCCCAATCGTCCGCGCGGCGCTCAAGTCACGACCGGCCGGCACCCGCAAGCGGGTGCGCCGCACGTCG
TGTGCGGCGCCGTACGCGGC

Downstream 100 bases:

>100_bases
CGGGGGCCGCACTGCACGCCACGGCCGGTGACATGAACTACGCGGCCGTCGGCCTGACGCTGAAGGCCGGCGCGCGCACG
CTGCTCGACGGCTTCACCCA

Product: ABC cobalamin/Fe3+-siderophore transporter, inner membrane subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSAARATAIWALLAAAVALLFVASLSIGSVPMSPWQALASLVPHGGDALFADIVRTLRLPRALAGFACGALLALAGALLQ
VLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFAGSLVSVALVLGLARRELWRGESRDASPRLLLTGVVIAA
GWGALVTLLLSLAPDARLRGIIFWLTGDLNGVTTPWFACGALLLAACVALPAAPQLNVLLRGDATALALGVPVARLRVRI
YLVASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGGGVMAADLLARTAIAPAQLPVGVMTALIGVP
VFLWMLLRRPMR

Sequences:

>Translated_332_residues
MSAARATAIWALLAAAVALLFVASLSIGSVPMSPWQALASLVPHGGDALFADIVRTLRLPRALAGFACGALLALAGALLQ
VLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFAGSLVSVALVLGLARRELWRGESRDASPRLLLTGVVIAA
GWGALVTLLLSLAPDARLRGIIFWLTGDLNGVTTPWFACGALLLAACVALPAAPQLNVLLRGDATALALGVPVARLRVRI
YLVASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGGGVMAADLLARTAIAPAQLPVGVMTALIGVP
VFLWMLLRRPMR
>Mature_331_residues
SAARATAIWALLAAAVALLFVASLSIGSVPMSPWQALASLVPHGGDALFADIVRTLRLPRALAGFACGALLALAGALLQV
LLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFAGSLVSVALVLGLARRELWRGESRDASPRLLLTGVVIAAG
WGALVTLLLSLAPDARLRGIIFWLTGDLNGVTTPWFACGALLLAACVALPAAPQLNVLLRGDATALALGVPVARLRVRIY
LVASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGGGVMAADLLARTAIAPAQLPVGVMTALIGVPV
FLWMLLRRPMR

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=341, Percent_Identity=36.0703812316716, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=38.9473684210526, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790740, Length=309, Percent_Identity=35.9223300970874, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786805, Length=287, Percent_Identity=38.3275261324042, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786347, Length=281, Percent_Identity=30.6049822064057, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786804, Length=328, Percent_Identity=36.890243902439, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33885; Mature: 33754

Theoretical pI: Translated: 11.85; Mature: 11.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAARATAIWALLAAAVALLFVASLSIGSVPMSPWQALASLVPHGGDALFADIVRTLRLP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
RALAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEHHH
FAGSLVSVALVLGLARRELWRGESRDASPRLLLTGVVIAAGWGALVTLLLSLAPDARLRG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHCE
IIFWLTGDLNGVTTPWFACGALLLAACVALPAAPQLNVLLRGDATALALGVPVARLRVRI
EEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCHHHHHHHHH
YLVASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGGGVMAADLLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHH
TAIAPAQLPVGVMTALIGVPVFLWMLLRRPMR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAARATAIWALLAAAVALLFVASLSIGSVPMSPWQALASLVPHGGDALFADIVRTLRLP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
RALAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEHHH
FAGSLVSVALVLGLARRELWRGESRDASPRLLLTGVVIAAGWGALVTLLLSLAPDARLRG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHCE
IIFWLTGDLNGVTTPWFACGALLLAACVALPAAPQLNVLLRGDATALALGVPVARLRVRI
EEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCHHHHHHHHH
YLVASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGGGVMAADLLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHH
TAIAPAQLPVGVMTALIGVPVFLWMLLRRPMR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA