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The map label for this gene is yfjP [H]

Identifier: 78066852

GI number: 78066852

Start: 2449704

End: 2450531

Strand: Reverse

Name: yfjP [H]

Synonym: Bcep18194_A5383

Alternate gene names: 78066852

Gene position: 2450531-2449704 (Counterclockwise)

Preceding gene: 78066853

Following gene: 78066851

Centisome position: 66.34

GC content: 68.72

Gene sequence:

>828_bases
ATGGCAACGGCCAGAAAAGCGCCGGTCAGGCGCGCGACCCCGGTCGCCGCGCGTCCGGCAGCCAAGCGCGTGCCGCCGGC
GAAGACGGACGCGACGCGCGCCGTGCCGAACGGCGCGCTCAACGGTCATGCGCAGCCGGCGGCTGCGCTGCCGGCTGCCG
ACGCGGCCCGCAAGGCCCGTGCGTCCGAAACGGACGGCGAGGAGGTCGTCGTGCGTCCTGCTTACTGGGACAAGGCATGC
GCGGACCTCGTCAAGCGCGACCGGATCCTGAAGAAACTGATTCCGAAGTTCGGTCCCGCGCATCTCGTGAAGCGCGGCGA
CCCGTTCGTCACGCTCGCGCGCTCGGTCGTCGGCCAGCAGATTTCGGTGCCGTCGGCGCAGTCGCTGTGGGCACGCATCG
GGGATGCCTGTCCGAAACTCGCGCCGCAGCCGGTGATCCGGCTCGGCGCGGACAAGCTGATCGCGTGCGGGCTGTCGAAG
CGCAAGACGGAATACATCCTCGATCTCGCGCAGCATTTCGTGTCGGGCGCGTTGCACGTCGACAAATGGACGTCGATGGA
CGACGAGGACGTGATCGCGGAACTCACGCAGATCCGCGGCATCAGCCGCTGGACGGCCGAGATGTTCCTGATCTTCAACC
TGTCGCGGCCGGACGTCCTGCCGCTCGACGACCCGGGCCTGATCCGCGCGATCAGTGTCAATTACTTCAGCGGGGAACCC
GTCACGCGCAGTGAGGCGCGCGAGGTTGCGGCCAACTGGGAACCGTGGCGCACCGTCGCGACCTGGTACATGTGGCGCAG
CCTCGATGCGCCCGACGCCGACGCCTGA

Upstream 100 bases:

>100_bases
ACCGGTATCGCACTTGAAGACAAACCGGGCGGATCGACCGAATGGCGTCGCGTATGAGCGCGGTGCGTTCCACTGACCGA
TCCGTCAGGTAGGAGGCAAG

Downstream 100 bases:

>100_bases
GCGGCGGCTATCGGGTTTTAAACATCAATAGTTGAGAGCCGGTTTTGAGCGTCGCCCGCGCGGGTAGAATACGCGCTGCC
GCAAGACCCAAGGATTCGAA

Product: 3-methyladenine DNA glycosylase/8- oxoguaninedna glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MATARKAPVRRATPVAARPAAKRVPPAKTDATRAVPNGALNGHAQPAAALPAADAARKARASETDGEEVVVRPAYWDKAC
ADLVKRDRILKKLIPKFGPAHLVKRGDPFVTLARSVVGQQISVPSAQSLWARIGDACPKLAPQPVIRLGADKLIACGLSK
RKTEYILDLAQHFVSGALHVDKWTSMDDEDVIAELTQIRGISRWTAEMFLIFNLSRPDVLPLDDPGLIRAISVNYFSGEP
VTRSEAREVAANWEPWRTVATWYMWRSLDAPDADA

Sequences:

>Translated_275_residues
MATARKAPVRRATPVAARPAAKRVPPAKTDATRAVPNGALNGHAQPAAALPAADAARKARASETDGEEVVVRPAYWDKAC
ADLVKRDRILKKLIPKFGPAHLVKRGDPFVTLARSVVGQQISVPSAQSLWARIGDACPKLAPQPVIRLGADKLIACGLSK
RKTEYILDLAQHFVSGALHVDKWTSMDDEDVIAELTQIRGISRWTAEMFLIFNLSRPDVLPLDDPGLIRAISVNYFSGEP
VTRSEAREVAANWEPWRTVATWYMWRSLDAPDADA
>Mature_274_residues
ATARKAPVRRATPVAARPAAKRVPPAKTDATRAVPNGALNGHAQPAAALPAADAARKARASETDGEEVVVRPAYWDKACA
DLVKRDRILKKLIPKFGPAHLVKRGDPFVTLARSVVGQQISVPSAQSLWARIGDACPKLAPQPVIRLGADKLIACGLSKR
KTEYILDLAQHFVSGALHVDKWTSMDDEDVIAELTQIRGISRWTAEMFLIFNLSRPDVLPLDDPGLIRAISVNYFSGEPV
TRSEAREVAANWEPWRTVATWYMWRSLDAPDADA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=206, Percent_Identity=31.5533980582524, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 30039; Mature: 29908

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATARKAPVRRATPVAARPAAKRVPPAKTDATRAVPNGALNGHAQPAAALPAADAARKAR
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHCCCCCCCCCCCCCHHHCCHHHHHHHHH
ASETDGEEVVVRPAYWDKACADLVKRDRILKKLIPKFGPAHLVKRGDPFVTLARSVVGQQ
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCC
ISVPSAQSLWARIGDACPKLAPQPVIRLGADKLIACGLSKRKTEYILDLAQHFVSGALHV
CCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCEEC
DKWTSMDDEDVIAELTQIRGISRWTAEMFLIFNLSRPDVLPLDDPGLIRAISVNYFSGEP
CCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCC
VTRSEAREVAANWEPWRTVATWYMWRSLDAPDADA
CCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATARKAPVRRATPVAARPAAKRVPPAKTDATRAVPNGALNGHAQPAAALPAADAARKAR
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHCCCCCCCCCCCCCHHHCCHHHHHHHHH
ASETDGEEVVVRPAYWDKACADLVKRDRILKKLIPKFGPAHLVKRGDPFVTLARSVVGQQ
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCC
ISVPSAQSLWARIGDACPKLAPQPVIRLGADKLIACGLSKRKTEYILDLAQHFVSGALHV
CCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCEEC
DKWTSMDDEDVIAELTQIRGISRWTAEMFLIFNLSRPDVLPLDDPGLIRAISVNYFSGEP
CCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCC
VTRSEAREVAANWEPWRTVATWYMWRSLDAPDADA
CCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]