Click here to switch to the map view.

The map label for this gene is cysS

Identifier: 78066853

GI number: 78066853

Start: 2450575

End: 2451972

Strand: Reverse

Name: cysS

Synonym: Bcep18194_A5384

Alternate gene names: 78066853

Gene position: 2451972-2450575 (Counterclockwise)

Preceding gene: 78066858

Following gene: 78066852

Centisome position: 66.37

GC content: 63.88

Gene sequence:

>1398_bases
ATGGAATCACTGCGCATCTACAACACGCTCGCGCGTGACAAGCAAGTTTTCGTGCCGCGCCAGTCCGGCGAAGTGCGGAT
GTACGTATGCGGAATCACCGTATACGACTATTGTCACGTGGGCCACGCGCGCATGCTGGTCGTGTTCGACCTCGTCCAGC
GCTGGTTGCGTGCGATCGGTTACCGGGTCACGTATGTGCGCAACATTACCGACATCGACGACAAGATCATCCGCCGCGCG
GTCGAGAACGGCGAGACGATCAAGTCGCTGACCGACCGGTTCATCGGCGCGATGCACGACGACGAAAGTGCGCTCGGCAT
CCAGCGGCCCGACATCGAGCCGCGCGCGACCGAGTTCATTCCGCAGATGCTCGGCATGATCGAGACGCTCGAGACGAACG
GTTACGCGTACCAGGCGACCGACGGCGACGTCAATTACTCGGTGCGCAAGTTCGCGAACTACGGAAAGCTGTCGGGCAAG
TCGCTGGACGATCTGCGCGCCGGCGAGCGCGTCGCCGCGAACGACGCGAAGGAAGATCCGCTCGATTTCGTGCTGTGGAA
ACGCGCGAAGCCGGAAGATCCGGAAGGCACGTCGTGGGCGTCGAAGTACGGGATGGGTCGCCCGGGCTGGCACATCGAGT
GCTCGGCGATGGGCTGCACGCTGCTCGGCGAGCATTTCGACATCCACGGTGGCGGGCAGGATCTGCAATTCCCGCACCAC
GAGAACGAGATCGCGCAGAGCGAAGGCGCGACCGGCCAGACGTTCGTCAATTACTGGATGCACAACGGCTTCGTGCAGGT
CGACAACGAGAAGATGTCGAAATCGCTCGGCAACTTCTTCACGATCCGCGAAGTGCTCGAGCGCTACGATGCCGAAGTCA
TGCGCTTCTTCATCGTGCGCACGCACTACCGTTCGCCGCTCAATTACAGCGACGTGCATCTCGACGATGCGCGTGCGTCG
CTCACGCGTCTCTACACCGCACTGAAAGATGTTGAAGCCGACACGCTCGCGCTCGACTGGAACGAGCCGCACGCGCAGCG
TTTCGCGGCCGCGATGAACGACGACTTCAACACGCCGGTCGCGGTGGCGACGCTGTTCGAGCTGGCGGGCGAGGTGAATC
GCACGCGCGACGCATCGCTCGCGCGGCAACTGAAACAGCTGGCGGGCCTGCTCGGCCTGCTGGGCCGCGAACCGCGCGCG
TTCCTGCAGCAGGCGTCCGGCGCCGCGCAGGCGGGCGGGCTCGCCGCCGACGAGATCGAAGCGAAAATCGCCGCGCGCGT
CGCGGCGAAGCAAGCGAAGGACTATGCCGAAGCGGACCGGATCCGGGCGGAACTGCTCGAGACCGGTATCGCACTTGAAG
ACAAACCGGGCGGATCGACCGAATGGCGTCGCGTATGA

Upstream 100 bases:

>100_bases
TCGAGGACGCTCGGCCTGGTGCCGCAGCAGATGGTCCGTCCGTTTCGCATGCTGGGCGAGCTTCGCCAGGGCGGTTTCCT
TCGGCTCACGGTTCATCTCT

Downstream 100 bases:

>100_bases
GCGCGGTGCGTTCCACTGACCGATCCGTCAGGTAGGAGGCAAGATGGCAACGGCCAGAAAAGCGCCGGTCAGGCGCGCGA
CCCCGGTCGCCGCGCGTCCG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase 2; CysRS 2

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MESLRIYNTLARDKQVFVPRQSGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIGAMHDDESALGIQRPDIEPRATEFIPQMLGMIETLETNGYAYQATDGDVNYSVRKFANYGKLSGK
SLDDLRAGERVAANDAKEDPLDFVLWKRAKPEDPEGTSWASKYGMGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEGATGQTFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDVEADTLALDWNEPHAQRFAAAMNDDFNTPVAVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRA
FLQQASGAAQAGGLAADEIEAKIAARVAAKQAKDYAEADRIRAELLETGIALEDKPGGSTEWRRV

Sequences:

>Translated_465_residues
MESLRIYNTLARDKQVFVPRQSGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIGAMHDDESALGIQRPDIEPRATEFIPQMLGMIETLETNGYAYQATDGDVNYSVRKFANYGKLSGK
SLDDLRAGERVAANDAKEDPLDFVLWKRAKPEDPEGTSWASKYGMGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEGATGQTFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDVEADTLALDWNEPHAQRFAAAMNDDFNTPVAVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRA
FLQQASGAAQAGGLAADEIEAKIAARVAAKQAKDYAEADRIRAELLETGIALEDKPGGSTEWRRV
>Mature_465_residues
MESLRIYNTLARDKQVFVPRQSGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIGAMHDDESALGIQRPDIEPRATEFIPQMLGMIETLETNGYAYQATDGDVNYSVRKFANYGKLSGK
SLDDLRAGERVAANDAKEDPLDFVLWKRAKPEDPEGTSWASKYGMGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEGATGQTFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDVEADTLALDWNEPHAQRFAAAMNDDFNTPVAVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRA
FLQQASGAAQAGGLAADEIEAKIAARVAAKQAKDYAEADRIRAELLETGIALEDKPGGSTEWRRV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=394, Percent_Identity=38.5786802030457, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI303304987, Length=280, Percent_Identity=36.7857142857143, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI62240992, Length=280, Percent_Identity=36.7857142857143, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI21269877, Length=280, Percent_Identity=36.7857142857143, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI10835051, Length=280, Percent_Identity=36.7857142857143, Blast_Score=184, Evalue=2e-46,
Organism=Escherichia coli, GI1786737, Length=467, Percent_Identity=55.6745182012848, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17509795, Length=236, Percent_Identity=37.2881355932203, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17509797, Length=236, Percent_Identity=37.2881355932203, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324082, Length=442, Percent_Identity=30.0904977375566, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19922218, Length=394, Percent_Identity=37.5634517766497, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI19922364, Length=338, Percent_Identity=32.8402366863905, Blast_Score=171, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC2_BURS3 (Q39EY8)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_369622.1
- ProteinModelPortal:   Q39EY8
- SMR:   Q39EY8
- STRING:   Q39EY8
- GeneID:   3750603
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A5384
- NMPDR:   fig|269483.3.peg.6761
- eggNOG:   COG0215
- HOGENOM:   HBG327651
- OMA:   DFDALNM
- ProtClustDB:   PRK00260
- BioCyc:   BSP36773:BCEP18194_A5384-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 52209; Mature: 52209

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLRIYNTLARDKQVFVPRQSGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIG
CCCCHHHHHHHCCCEEEEECCCCCEEEEEECEEHHHHHHCCHHHHHHHHHHHHHHHHHHC
YRVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIGAMHDDESALGIQRPDIEPRATEFI
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
PQMLGMIETLETNGYAYQATDGDVNYSVRKFANYGKLSGKSLDDLRAGERVAANDAKEDP
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKRAKPEDPEGTSWASKYGMGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
HHHHEECCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHCCCEEECCCCCCCCCCCC
ENEIAQSEGATGQTFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVR
CHHHHHCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THYRSPLNYSDVHLDDARASLTRLYTALKDVEADTLALDWNEPHAQRFAAAMNDDFNTPV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
AVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRAFLQQASGAAQAGGLAADEIE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCHHHHH
AKIAARVAAKQAKDYAEADRIRAELLETGIALEDKPGGSTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MESLRIYNTLARDKQVFVPRQSGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIG
CCCCHHHHHHHCCCEEEEECCCCCEEEEEECEEHHHHHHCCHHHHHHHHHHHHHHHHHHC
YRVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIGAMHDDESALGIQRPDIEPRATEFI
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
PQMLGMIETLETNGYAYQATDGDVNYSVRKFANYGKLSGKSLDDLRAGERVAANDAKEDP
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKRAKPEDPEGTSWASKYGMGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
HHHHEECCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHCCCEEECCCCCCCCCCCC
ENEIAQSEGATGQTFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVR
CHHHHHCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THYRSPLNYSDVHLDDARASLTRLYTALKDVEADTLALDWNEPHAQRFAAAMNDDFNTPV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
AVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRAFLQQASGAAQAGGLAADEIE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCHHHHH
AKIAARVAAKQAKDYAEADRIRAELLETGIALEDKPGGSTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA