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The map label for this gene is frr

Identifier: 78066795

GI number: 78066795

Start: 2378808

End: 2379368

Strand: Reverse

Name: frr

Synonym: Bcep18194_A5326

Alternate gene names: 78066795

Gene position: 2379368-2378808 (Counterclockwise)

Preceding gene: 78066796

Following gene: 78066794

Centisome position: 64.41

GC content: 61.68

Gene sequence:

>561_bases
ATGAGTGTCGCTGATACCAAGAAGGGCGTCGAGCAGAAGATGCAGCGCTCGATCGATGCATTCAAGAGCGATCTGGCGAA
GATCCGTACGGGCCGTGCGCACACCGGCATGCTCGATCACGTGCAGGTTGACTACTACGGGTCGATGGTGCCGATTTCGC
AGGTTGCCAACATGACGCTCGTCGACGCGCGCACGATCGGTGTGCAGCCGTGGGAAAAGCCGATGGTTGCGAAGGTCGAG
AAGGCCATTCGCGAAGCCGATCTCGGCCTGAACCCGGCAACGTCCGGCGACCAGATCCGCGTGCCGATGCCCGCGCTGAC
GGAAGAGCGCCGCCGCGAGCTGACCAAGGTCGTCAAGAGCGAAGGCGAAACGGCCAAGGTCGCGATCCGCAACCTGCGTC
GCGACGCGAACGAAGCGCTCAAGAAGCTCGTGAAGGACAAGGAAATCTCGGAAGACGACGAGCGCCGCGCGAGCGACGAC
GTGCAGAAGCTGACCGACAAGCACGTTGCCGAAATCGACAAGCTCGTGCAGAGCAAGGAAGCCGAGATCATGACGGTCTG
A

Upstream 100 bases:

>100_bases
CACGTGTAAACTCCCGCGGATGCGGGCCATCGGCCGCGGCGCGCCAGATGCGCCAGGTGGGGTCCGCGTTCTTTGAAGGT
TTGAAGGTTCGGAGGTTGAA

Downstream 100 bases:

>100_bases
CGACCGTCCTCGCGCGCCGCCTTCTTCCCGCATTACTGTCTCAACGGCCATGACCTATACCAGCTCTACCGTTCGCGTGC
CTGACGTCGGCGTCGTGCCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVADTKKGVEQKMQRSIDAFKSDLAKIRTGRAHTGMLDHVQVDYYGSMVPISQVANMTLVDARTIGVQPWEKPMVAKVE
KAIREADLGLNPATSGDQIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDD
VQKLTDKHVAEIDKLVQSKEAEIMTV

Sequences:

>Translated_186_residues
MSVADTKKGVEQKMQRSIDAFKSDLAKIRTGRAHTGMLDHVQVDYYGSMVPISQVANMTLVDARTIGVQPWEKPMVAKVE
KAIREADLGLNPATSGDQIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDD
VQKLTDKHVAEIDKLVQSKEAEIMTV
>Mature_185_residues
SVADTKKGVEQKMQRSIDAFKSDLAKIRTGRAHTGMLDHVQVDYYGSMVPISQVANMTLVDARTIGVQPWEKPMVAKVEK
AIREADLGLNPATSGDQIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDV
QKLTDKHVAEIDKLVQSKEAEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32.6666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=51.6483516483517, Blast_Score=203, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=29.9435028248588, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20824; Mature: 20693

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADTKKGVEQKMQRSIDAFKSDLAKIRTGRAHTGMLDHVQVDYYGSMVPISQVANMTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHCCCCCCHHHHHCCHH
VDARTIGVQPWEKPMVAKVEKAIREADLGLNPATSGDQIRVPMPALTEERRRELTKVVKS
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHC
EGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDVQKLTDKHVAEIDKLVQSKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEIMTV
CCEECC
>Mature Secondary Structure 
SVADTKKGVEQKMQRSIDAFKSDLAKIRTGRAHTGMLDHVQVDYYGSMVPISQVANMTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHCCCCCCHHHHHCCHH
VDARTIGVQPWEKPMVAKVEKAIREADLGLNPATSGDQIRVPMPALTEERRRELTKVVKS
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHC
EGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDVQKLTDKHVAEIDKLVQSKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEIMTV
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA