Click here to switch to the map view.

The map label for this gene is lpxA [H]

Identifier: 78066786

GI number: 78066786

Start: 2369094

End: 2369882

Strand: Reverse

Name: lpxA [H]

Synonym: Bcep18194_A5317

Alternate gene names: 78066786

Gene position: 2369882-2369094 (Counterclockwise)

Preceding gene: 78066787

Following gene: 78066785

Centisome position: 64.15

GC content: 65.15

Gene sequence:

>789_bases
ATGACCAGGATTCATCCCACCGCGATTGTCGAACCGGGCGCGCAGATCGACGAATCGGTCGAGATCGGTCCGTACGCGAT
CGTCGGTCCGCATGTCACGATCGGCGCGCGGACGACGATCGGCTCGCACAGCGTGATCGAAGGCCATACGACGCTCGGCG
AGGACAACCGCATCGGCCATTACGCGTCGGTCGGTGGTCGTCCGCAGGACATGAAGTACAAGGACGAGCCGACGAAGCTC
GTGATCGGCAACCGCAACACGATCCGCGAATTCACGACGATCCACACGGGTACCGTGCAGGACGTCGGCGTGACGACGCT
CGGTGACGACAACTGGATCATGGCCTATGTGCACATCGGTCATGACTGCACCGTCGGCAACCACGTGATCCTGTCGAGCA
ACGCACAGATGGCCGGCCACGTCGAGATCGGCGACTGGGCGATCGTCGGCGGGATGTCGGGCGTCCACCAGTTCGTGCGC
ATCGGTGCGCACTCGATGCTGGGCGGTGCGTCCGCGCTCGTGCAGGACATTCCGCCGTTCGTGATCGCGGCAGGCAACAA
GGCCGAGCCGCACGGGATCAACGTCGAAGGGTTGCGCCGGCGCGGTTTCTCGCCCGACGCGATCTCCGCGCTGCGCAGCG
CGTACCGCCTGCTGTACAAGAACGGCCTGTCGTTCGAGGAAGCGAAAGTGCAGTTGCGCGAGCTGGCCGCCGCGGGCGGC
GAGGGCGACGCAGCCGTGAAGACGCTCGTCGAGTTCATCGACGCGTCGCAACGCGGCATCATCCGCTAA

Upstream 100 bases:

>100_bases
GAGCTGATGTGCACGGTCAAGACGACCGACGTGGCGCCCTGAGCGACGCGGCACGGACAGGCAACGCAACGCGACACATC
ACATCGAGAGGCAACGGCGC

Downstream 100 bases:

>100_bases
GCGATGCCGCTTCCGACCTCTCAGCTCCGGCTCGCGATGGTGGCCGGCGAACCGTCGGGCGACCTGCTCGGCGCGTCGCT
GCTCGGCGGGCTGCGCGAGC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTKL
VIGNRNTIREFTTIHTGTVQDVGVTTLGDDNWIMAYVHIGHDCTVGNHVILSSNAQMAGHVEIGDWAIVGGMSGVHQFVR
IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRLLYKNGLSFEEAKVQLRELAAAGG
EGDAAVKTLVEFIDASQRGIIR

Sequences:

>Translated_262_residues
MTRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTKL
VIGNRNTIREFTTIHTGTVQDVGVTTLGDDNWIMAYVHIGHDCTVGNHVILSSNAQMAGHVEIGDWAIVGGMSGVHQFVR
IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRLLYKNGLSFEEAKVQLRELAAAGG
EGDAAVKTLVEFIDASQRGIIR
>Mature_261_residues
TRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTKLV
IGNRNTIREFTTIHTGTVQDVGVTTLGDDNWIMAYVHIGHDCTVGNHVILSSNAQMAGHVEIGDWAIVGGMSGVHQFVRI
GAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRLLYKNGLSFEEAKVQLRELAAAGGE
GDAAVKTLVEFIDASQRGIIR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=259, Percent_Identity=54.4401544401544, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27913; Mature: 27782

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGH
CCCCCCCEEECCCCCCCCCCCCCCEEEECCEEEECCEEECCCCCEEECCCCCCCCCCCCC
YASVGGRPQDMKYKDEPTKLVIGNRNTIREFTTIHTGTVQDVGVTTLGDDNWIMAYVHIG
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHEEEEECCCCCCCCEEEECCCCEEEEEEEEC
HDCTVGNHVILSSNAQMAGHVEIGDWAIVGGMSGVHQFVRIGAHSMLGGASALVQDIPPF
CCCCCCCEEEEECCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCE
VIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRLLYKNGLSFEEAKVQLRELAAAGG
EEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
EGDAAVKTLVEFIDASQRGIIR
CCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGH
CCCCCCEEECCCCCCCCCCCCCCEEEECCEEEECCEEECCCCCEEECCCCCCCCCCCCC
YASVGGRPQDMKYKDEPTKLVIGNRNTIREFTTIHTGTVQDVGVTTLGDDNWIMAYVHIG
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHEEEEECCCCCCCCEEEECCCCEEEEEEEEC
HDCTVGNHVILSSNAQMAGHVEIGDWAIVGGMSGVHQFVRIGAHSMLGGASALVQDIPPF
CCCCCCCEEEEECCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCE
VIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRLLYKNGLSFEEAKVQLRELAAAGG
EEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
EGDAAVKTLVEFIDASQRGIIR
CCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA