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The map label for this gene is fabZ

Identifier: 78066787

GI number: 78066787

Start: 2369941

End: 2370408

Strand: Reverse

Name: fabZ

Synonym: Bcep18194_A5318

Alternate gene names: 78066787

Gene position: 2370408-2369941 (Counterclockwise)

Preceding gene: 78066788

Following gene: 78066786

Centisome position: 64.17

GC content: 60.9

Gene sequence:

>468_bases
ATGAGCACTGAAAAAATCAATCTCGACATCCACAAGATCCTCACGCTGCTGCCGCATCGCTACCCGATTCTGCTCGTCGA
TCGCGTGCTCGAACTCGAACCGCACAAGGGAATCAAAGCGCTGAAGAACGTGTCGATCAACGAGCCGTACTTCCAGGGGC
ATTTCCCGAAGCGGCCGGTGATGCCGGGCGTGCTGATCCTCGAAGCGCTTGCGCAGGCCGCGGCGCTGCTGACCTTCTCG
GAAGAGCAGCCGAAGGATCCGGAGAACACGCTGTACTACTTCGTCGGGATCGACGGCGCGCGCTTCAAGCGTCCGGTCGA
GCCGGGCGACCAACTGATTCTGAACGTGACGTTCGAACGCTACATCCGCGGCATCTGGAAATTCAAGGCGGTGGCGGAAG
TGGACGGCAAGGTGGCGGCGGAAGCCGAGCTGATGTGCACGGTCAAGACGACCGACGTGGCGCCCTGA

Upstream 100 bases:

>100_bases
CGGCCAGCGCAACCGGCCCGGTTTGCCAGACTGGGCCGCACGGCGGCCCGCTTCAGCCTTTGCATCACCACCGCGCAGCC
TCTGCGTGAGACGAACCATC

Downstream 100 bases:

>100_bases
GCGACGCGGCACGGACAGGCAACGCAACGCGACACATCACATCGAGAGGCAACGGCGCATGACCAGGATTCATCCCACCG
CGATTGTCGAACCGGGCGCG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPYFQGHFPKRPVMPGVLILEALAQAAALLTFS
EEQPKDPENTLYYFVGIDGARFKRPVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTTDVAP

Sequences:

>Translated_155_residues
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPYFQGHFPKRPVMPGVLILEALAQAAALLTFS
EEQPKDPENTLYYFVGIDGARFKRPVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTTDVAP
>Mature_154_residues
STEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPYFQGHFPKRPVMPGVLILEALAQAAALLTFSE
EQPKDPENTLYYFVGIDGARFKRPVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTTDVAP

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=59.5890410958904, Blast_Score=182, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17481; Mature: 17349

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPYFQGHFPKRPV
CCCCEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCC
MPGVLILEALAQAAALLTFSEEQPKDPENTLYYFVGIDGARFKRPVEPGDQLILNVTFER
CCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEHHH
YIRGIWKFKAVAEVDGKVAAEAELMCTVKTTDVAP
HHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC
>Mature Secondary Structure 
STEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPYFQGHFPKRPV
CCCEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCC
MPGVLILEALAQAAALLTFSEEQPKDPENTLYYFVGIDGARFKRPVEPGDQLILNVTFER
CCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEHHH
YIRGIWKFKAVAEVDGKVAAEAELMCTVKTTDVAP
HHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA