Click here to switch to the map view.

The map label for this gene is ldcA

Identifier: 78066751

GI number: 78066751

Start: 2337348

End: 2338286

Strand: Reverse

Name: ldcA

Synonym: Bcep18194_A5282

Alternate gene names: 78066751

Gene position: 2338286-2337348 (Counterclockwise)

Preceding gene: 78066752

Following gene: 78066750

Centisome position: 63.3

GC content: 68.26

Gene sequence:

>939_bases
ATGTCCTTCCAGCCCGCTGCGTCCTACACCATCCGCCTGCTTGCGCCGTCCGGCTATCCGCACGACCCGGACGCAATCAA
TCGCGCGCTCGAACGCCTCAGCACCGCACAGCACCGCATCGAGAACATCGAAGCGACGCAGCGGCGCTTCCAGCGGTTCG
GCGGCACCGACGGCGAGCGGGCAGGCGACCTGAACCGCCTTGCCGATCCCGAGCGGCCGCTGCCGGACATCGCGCTCGCG
GTGCGCGGCGGCTACGGCGCCGCGCGCATCCTGCACGGGCTCGACTATCGCGGGCTCGAGCGCAGGCTCCGCGACCAGCC
GGTCGCGCTCGTCGGCCACAGCGACTTCACGGCGCTCCAGCTCGCGCTGTACGCGAAGGCGCGCATCAAGACGTTCGGCG
GCCCGATGCTGTCCGCCGACTTCGGCGCGGAAACGCCGAGCGATTTCACGATGCAGCACTTCTGGCAGACGCTGACGCAG
CCGAGCACGACGATCATCGCCGAAGCGCCGCAAGTGCAGAGCGTGAACGTGACGGGCACGCTGTGGGGCGGCAACCTGGC
GATCCTCACGTCGCTGGTCGGCACGCCGTACATGCCCGACATCGAAGGCGGCATCCTGTTCATCGAGGACGTGAACGAGC
AGCCGTTCCGGATCGAACGGATGATCTACCAACTGCACCTGTCGGGGCTGCTCGCGCGCCAGCAGGCGCTCGTGCTCGGC
CAGTTCACCGGCGCGCGGCCGTTCGAGTACGACAACGGCTACGACATGCAGGCGATGATCGACCAGGTGCGTGAGGTGGT
CGGCATCCCGGTCGTGACGGGGCTCCAGTTCGGCCACGTGCCCGATCTGCTGACGCTGCCGTTCGGCGCGCAGGCGCAAC
TGGTCGCGAACGCGCATGGTTTCCGCCTCACTTTGTCGGACTATCCGCACCTCGGATGA

Upstream 100 bases:

>100_bases
GCGCCCGTCGCACGGTGCGAGCGGGGCGCGCACGGTTCCGTGAACCGGAGACGGTTCGGACCCTCTAAGCAGGTTTGACG
ACCCGACACCTCTCTTCGCC

Downstream 100 bases:

>100_bases
GGCTGACGCAGTCGGTCGAAAGGCGGGTTTCCCGCCTTTTTCTTTATGTAAACACGCAACTAACGGTCTATATTTTTTGT
CGACGCAAACAGGGTCTGCG

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSFQPAASYTIRLLAPSGYPHDPDAINRALERLSTAQHRIENIEATQRRFQRFGGTDGERAGDLNRLADPERPLPDIALA
VRGGYGAARILHGLDYRGLERRLRDQPVALVGHSDFTALQLALYAKARIKTFGGPMLSADFGAETPSDFTMQHFWQTLTQ
PSTTIIAEAPQVQSVNVTGTLWGGNLAILTSLVGTPYMPDIEGGILFIEDVNEQPFRIERMIYQLHLSGLLARQQALVLG
QFTGARPFEYDNGYDMQAMIDQVREVVGIPVVTGLQFGHVPDLLTLPFGAQAQLVANAHGFRLTLSDYPHLG

Sequences:

>Translated_312_residues
MSFQPAASYTIRLLAPSGYPHDPDAINRALERLSTAQHRIENIEATQRRFQRFGGTDGERAGDLNRLADPERPLPDIALA
VRGGYGAARILHGLDYRGLERRLRDQPVALVGHSDFTALQLALYAKARIKTFGGPMLSADFGAETPSDFTMQHFWQTLTQ
PSTTIIAEAPQVQSVNVTGTLWGGNLAILTSLVGTPYMPDIEGGILFIEDVNEQPFRIERMIYQLHLSGLLARQQALVLG
QFTGARPFEYDNGYDMQAMIDQVREVVGIPVVTGLQFGHVPDLLTLPFGAQAQLVANAHGFRLTLSDYPHLG
>Mature_311_residues
SFQPAASYTIRLLAPSGYPHDPDAINRALERLSTAQHRIENIEATQRRFQRFGGTDGERAGDLNRLADPERPLPDIALAV
RGGYGAARILHGLDYRGLERRLRDQPVALVGHSDFTALQLALYAKARIKTFGGPMLSADFGAETPSDFTMQHFWQTLTQP
STTIIAEAPQVQSVNVTGTLWGGNLAILTSLVGTPYMPDIEGGILFIEDVNEQPFRIERMIYQLHLSGLLARQQALVLGQ
FTGARPFEYDNGYDMQAMIDQVREVVGIPVVTGLQFGHVPDLLTLPFGAQAQLVANAHGFRLTLSDYPHLG

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=301, Percent_Identity=47.8405315614618, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 34336; Mature: 34204

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQPAASYTIRLLAPSGYPHDPDAINRALERLSTAQHRIENIEATQRRFQRFGGTDGER
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGDLNRLADPERPLPDIALAVRGGYGAARILHGLDYRGLERRLRDQPVALVGHSDFTALQ
CCCHHHHCCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEEECCCHHHHH
LALYAKARIKTFGGPMLSADFGAETPSDFTMQHFWQTLTQPSTTIIAEAPQVQSVNVTGT
HHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEE
LWGGNLAILTSLVGTPYMPDIEGGILFIEDVNEQPFRIERMIYQLHLSGLLARQQALVLG
ECCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
QFTGARPFEYDNGYDMQAMIDQVREVVGIPVVTGLQFGHVPDLLTLPFGAQAQLVANAHG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCEEEEECCCC
FRLTLSDYPHLG
EEEEECCCCCCC
>Mature Secondary Structure 
SFQPAASYTIRLLAPSGYPHDPDAINRALERLSTAQHRIENIEATQRRFQRFGGTDGER
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGDLNRLADPERPLPDIALAVRGGYGAARILHGLDYRGLERRLRDQPVALVGHSDFTALQ
CCCHHHHCCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEEECCCHHHHH
LALYAKARIKTFGGPMLSADFGAETPSDFTMQHFWQTLTQPSTTIIAEAPQVQSVNVTGT
HHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEE
LWGGNLAILTSLVGTPYMPDIEGGILFIEDVNEQPFRIERMIYQLHLSGLLARQQALVLG
ECCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
QFTGARPFEYDNGYDMQAMIDQVREVVGIPVVTGLQFGHVPDLLTLPFGAQAQLVANAHG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCEEEEECCCC
FRLTLSDYPHLG
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]