Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 78066752

GI number: 78066752

Start: 2338398

End: 2338877

Strand: Reverse

Name: tadA [H]

Synonym: Bcep18194_A5283

Alternate gene names: 78066752

Gene position: 2338877-2338398 (Counterclockwise)

Preceding gene: 78066753

Following gene: 78066751

Centisome position: 63.31

GC content: 70.21

Gene sequence:

>480_bases
ATGCGTCTTGCGCAGGCTGCCGCCGAAGAGGCGCGCGCGGCCGGCGAAGTGCCGGTCGGGGCGGTGCTCGTGCGTGGCGA
CGAAGTGATCGCACGCGGCTTCAACCATCCGATCGGCGGGCACGACCCGTCGGCCCATGCGGAAATGGCCGCGCTGCGCA
TGGCCGCGCAGCATCTGCAGAATTACCGGATGCCCGGCTGCGAGCTGTACGTGACGCTCGAGCCGTGCCTGATGTGCGCG
GGCGCGATCATGCATGCACGCATCGCACGGGTCGTCTACGGTGCCGCCGATCCGAAGACGGGCGCGTGCGGCAGCGTGAT
CGACGCGTTCGCGAATCCGCAACTGAACCACCATACCGAAGTGACCGGCGGCGTGCTCGCCGACGAGTGCGGCGCCGCGC
TGAAGTCGTTCTTCGCCGAGCGTCGTCGCGCGCTGCGCGAAGCGCGGCTCGCCCGCGACGCCGAATCCGGCGCGTCATAG

Upstream 100 bases:

>100_bases
GCACGACGCAGCCCGGTCGGCAGCCGCCCCGGCGGCCGAATCCGCCGCCGATTCCCCGGTTCCCGAAGCCGCGCCCGTAT
CGGCGCGCGACCTGCATTTC

Downstream 100 bases:

>100_bases
GCGCGTCCGCCGCGCCCGTCGCACGGTGCGAGCGGGGCGCGCACGGTTCCGTGAACCGGAGACGGTTCGGACCCTCTAAG
CAGGTTTGACGACCCGACAC

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRLAQAAAEEARAAGEVPVGAVLVRGDEVIARGFNHPIGGHDPSAHAEMAALRMAAQHLQNYRMPGCELYVTLEPCLMCA
GAIMHARIARVVYGAADPKTGACGSVIDAFANPQLNHHTEVTGGVLADECGAALKSFFAERRRALREARLARDAESGAS

Sequences:

>Translated_159_residues
MRLAQAAAEEARAAGEVPVGAVLVRGDEVIARGFNHPIGGHDPSAHAEMAALRMAAQHLQNYRMPGCELYVTLEPCLMCA
GAIMHARIARVVYGAADPKTGACGSVIDAFANPQLNHHTEVTGGVLADECGAALKSFFAERRRALREARLARDAESGAS
>Mature_159_residues
MRLAQAAAEEARAAGEVPVGAVLVRGDEVIARGFNHPIGGHDPSAHAEMAALRMAAQHLQNYRMPGCELYVTLEPCLMCA
GAIMHARIARVVYGAADPKTGACGSVIDAFANPQLNHHTEVTGGVLADECGAALKSFFAERRRALREARLARDAESGAS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=148, Percent_Identity=35.1351351351351, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI19923945, Length=69, Percent_Identity=52.1739130434783, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=53.2467532467532, Blast_Score=170, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17541138, Length=139, Percent_Identity=36.6906474820144, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=100, Percent_Identity=38, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355527, Length=144, Percent_Identity=37.5, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16746; Mature: 16746

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAQAAAEEARAAGEVPVGAVLVRGDEVIARGFNHPIGGHDPSAHAEMAALRMAAQHLQ
CCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NYRMPGCELYVTLEPCLMCAGAIMHARIARVVYGAADPKTGACGSVIDAFANPQLNHHTE
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCC
VTGGVLADECGAALKSFFAERRRALREARLARDAESGAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLAQAAAEEARAAGEVPVGAVLVRGDEVIARGFNHPIGGHDPSAHAEMAALRMAAQHLQ
CCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NYRMPGCELYVTLEPCLMCAGAIMHARIARVVYGAADPKTGACGSVIDAFANPQLNHHTE
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCC
VTGGVLADECGAALKSFFAERRRALREARLARDAESGAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]