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The map label for this gene is acoR [H]

Identifier: 78066612

GI number: 78066612

Start: 2188886

End: 2190802

Strand: Direct

Name: acoR [H]

Synonym: Bcep18194_A5143

Alternate gene names: 78066612

Gene position: 2188886-2190802 (Clockwise)

Preceding gene: 78066605

Following gene: 78066615

Centisome position: 59.25

GC content: 70.42

Gene sequence:

>1917_bases
ATGCCTTACGCCGTCCCCCAGGCCCAGCACGCCGACCGTGTGCTCGGCGCGCTCGCCGGACGCCTGCCCGCGCCGGCCGA
ATCCACGCGCCTCGTGTCGTCGTGGCAACGGTCGCTGGAGCGCTACTGTCTCGACCCCGCTTCTTCGATCGGCCCGCGCG
TGCTGACCGCGGCCGAGCTGCGTGAAGTGCGCGACAAGGAGGAAGCCTTCCTGCGTGCGTCGGGCCAATGCCTGACGCGG
CTGCACGACATGATCCGCGTCGCCGACTACTGCGTGATGCTGACCGACGCGCACGGCGTGACGATCGACTACCGGATCGA
CCGCGAGCGCCGCAACGACTTCCGCCATGCCGGGCTGCACATCGGCTCGTGCTGGTCGGAAAGCGAGGAAGGCACATGCG
GTGTCGCGAATGTGCTGACCGATCTCGCGCCGATCACCGTACACAAGACCGATCACTTTCGCGCGGCATTCACGACGCTC
ACCTGCAGCGCCGCGCCGATCTTCTCGCCGGGCGGCGAACTGATCGGCGTGCTCGACGCGTCGGCCGTTCATTCACCCGA
CGGCCGCGACAGCCAGCGTCTCGTCTATCAGCTCGTGCGGCAGAGCGCGGCGCTGATCGAGGATGGCTACTTCGTGCACA
GCACCGCGCAGCACTGGATCCTGTTCGGGCATCCGAATCGTCACTACGTCGAAGCGCAACCGGAGTGGCTGATCGCGTTC
GACGAATGCGGCAACATCGTCGCCGCGAACCGGCAGGCGCGCGACGCGCTGCCGGCGCTGCGCGAACCGCGCCATATCGA
CGAGATCTTCGATGCGACCGAGATGCCGCTGCGCGATGCCGCGCGGCTCGATGCGATCGTCGCGCTGCGGCTGCGCGCAA
CCGGTGCGCCGCTCTATGCGCGGCTGCGTGCACCGCTACGGCGCCCCGGCCGCGAACCCGGCACGGCCTCGCGCCGCCCG
GGCACCGCGCAACGCCACGTCGGCGCGCTGACGCCGTTCCTGCACAGCAACGACGCGCATATCGCGCAACAGGCCGAGCT
CGCGCTGCGCGTCGCGAGCAAGCGGCTGCCGATTCTCGTGCTCGGCGAAACCGGTGCGGGGAAGGAAGTATTCGCGCGCG
CGATCCACGATGCCGGTGCGCGGCGCGCTCGGCCGTTCGTCGCGGTCAACTGCGGCGCGCTGCCGGAAGCGCTGATCGAG
AGCGAACTGTTCGGCTATGCGGCCGGCGCGTTCACCGGCGCACGCAAGCATGGCGCGCGCGGCAAGATCGCGCTCGCCGA
CGGCGGCACGCTGTTCCTCGACGAAATCGGCGACATGCCGCTCGCGTTGCAGACGCGCCTGCTGCGCGTGCTCTCCGATG
GCGAAGTCGTGCCGCTCGGCAGCGACACGCCCGTACGCGTCGATCTCGACGTGATCTGCGCGACGCACCGCGATCTCGCA
CGCATGGTGGCCGACGGCACGTTCCGCGAGGACCTGTACTACCGGCTGAGCGGCGCGACGTTCGAACTGCCGCCGCTGCG
CGAGCGCGCCGATGTGCGCGACGTGATCGCCGCCGTATTCGCCGAAGAGGCGCAGGCAACCGGCCACGTGCTGACGCTCG
ATGCGACGCTCGCCGAACAGCTCGCCGCGTATCCGTGGCCCGGCAATGTGCGGCAATTGCGCAACGTGCTGCGCTATGCG
TGCGCGGTGTGCGACGCCGCGCGCGTGACGCGGCAGGATCTGCCGGCCGATATCGCCGCGCAGCTCGGCGGCACGTCGCC
CGGCATGCTGCCCGACGACGAACGCGGCCGCATCGTCGCGGCGCTCACCGCACATCGCTGGCGGCCCGACGCGGCCGCGC
AGGCGCTCGGCATCTCGCGCGCGACGCTGTACCGACGCATCGCGAAGCACCGGATCGTCGCGCCACATCGCGCGTGA

Upstream 100 bases:

>100_bases
ACGTCTCACGCCCGCCGCGTGCTGCGATGCAATGTGATCCGTCGAACCGGATGTGCTACAAGAACATCGCATCCCCCGCC
GTACGGAACCGGAGCCGACC

Downstream 100 bases:

>100_bases
CGCGCTGGCGCGCGCTTCGTCATGCGGGCTGCCCGGCCGCTTCGTTCACGTCTGCCGCATTGCCGGCCGCTTCATCACGC
CGCGTAAACACTTCGTGCGC

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MPYAVPQAQHADRVLGALAGRLPAPAESTRLVSSWQRSLERYCLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTR
LHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVANVLTDLAPITVHKTDHFRAAFTTL
TCSAAPIFSPGGELIGVLDASAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
DECGNIVAANRQARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRLRATGAPLYARLRAPLRRPGREPGTASRRP
GTAQRHVGALTPFLHSNDAHIAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRARPFVAVNCGALPEALIE
SELFGYAAGAFTGARKHGARGKIALADGGTLFLDEIGDMPLALQTRLLRVLSDGEVVPLGSDTPVRVDLDVICATHRDLA
RMVADGTFREDLYYRLSGATFELPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQLAAYPWPGNVRQLRNVLRYA
CAVCDAARVTRQDLPADIAAQLGGTSPGMLPDDERGRIVAALTAHRWRPDAAAQALGISRATLYRRIAKHRIVAPHRA

Sequences:

>Translated_638_residues
MPYAVPQAQHADRVLGALAGRLPAPAESTRLVSSWQRSLERYCLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTR
LHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVANVLTDLAPITVHKTDHFRAAFTTL
TCSAAPIFSPGGELIGVLDASAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
DECGNIVAANRQARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRLRATGAPLYARLRAPLRRPGREPGTASRRP
GTAQRHVGALTPFLHSNDAHIAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRARPFVAVNCGALPEALIE
SELFGYAAGAFTGARKHGARGKIALADGGTLFLDEIGDMPLALQTRLLRVLSDGEVVPLGSDTPVRVDLDVICATHRDLA
RMVADGTFREDLYYRLSGATFELPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQLAAYPWPGNVRQLRNVLRYA
CAVCDAARVTRQDLPADIAAQLGGTSPGMLPDDERGRIVAALTAHRWRPDAAAQALGISRATLYRRIAKHRIVAPHRA
>Mature_637_residues
PYAVPQAQHADRVLGALAGRLPAPAESTRLVSSWQRSLERYCLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTRL
HDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVANVLTDLAPITVHKTDHFRAAFTTLT
CSAAPIFSPGGELIGVLDASAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAFD
ECGNIVAANRQARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRLRATGAPLYARLRAPLRRPGREPGTASRRPG
TAQRHVGALTPFLHSNDAHIAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRARPFVAVNCGALPEALIES
ELFGYAAGAFTGARKHGARGKIALADGGTLFLDEIGDMPLALQTRLLRVLSDGEVVPLGSDTPVRVDLDVICATHRDLAR
MVADGTFREDLYYRLSGATFELPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQLAAYPWPGNVRQLRNVLRYAC
AVCDAARVTRQDLPADIAAQLGGTSPGMLPDDERGRIVAALTAHRWRPDAAAQALGISRATLYRRIAKHRIVAPHRA

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=41.0094637223975, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI87082117, Length=311, Percent_Identity=42.1221864951768, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI1788905, Length=229, Percent_Identity=46.7248908296943, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1789087, Length=299, Percent_Identity=42.1404682274247, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1788550, Length=297, Percent_Identity=38.7205387205387, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI1790437, Length=293, Percent_Identity=41.9795221843003, Blast_Score=198, Evalue=9e-52,
Organism=Escherichia coli, GI1790299, Length=314, Percent_Identity=38.8535031847134, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1786524, Length=294, Percent_Identity=44.5578231292517, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87082152, Length=259, Percent_Identity=43.2432432432432, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1787583, Length=277, Percent_Identity=38.2671480144404, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081872, Length=298, Percent_Identity=37.248322147651, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI87081858, Length=562, Percent_Identity=25.4448398576512, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1789828, Length=271, Percent_Identity=35.4243542435424, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69605; Mature: 69474

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYAVPQAQHADRVLGALAGRLPAPAESTRLVSSWQRSLERYCLDPASSIGPRVLTAAEL
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHH
REVRDKEEAFLRASGQCLTRLHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHHHHHHCCE
IGSCWSESEEGTCGVANVLTDLAPITVHKTDHFRAAFTTLTCSAAPIFSPGGELIGVLDA
EECCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHEEHHEEEECCCCCCCCCCCEEEEEEH
SAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCEEECCCCEEEEE
DECGNIVAANRQARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRLRATGAPLYA
HHCCCEEECCCHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHEEEEECCCCCHHH
RLRAPLRRPGREPGTASRRPGTAQRHVGALTPFLHSNDAHIAQQAELALRVASKRLPILV
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCEEE
LGETGAGKEVFARAIHDAGARRARPFVAVNCGALPEALIESELFGYAAGAFTGARKHGAR
EECCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GKIALADGGTLFLDEIGDMPLALQTRLLRVLSDGEVVPLGSDTPVRVDLDVICATHRDLA
CEEEEECCCEEEEHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEHHEEEHHHHHHH
RMVADGTFREDLYYRLSGATFELPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQ
HHHHCCCHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
LAAYPWPGNVRQLRNVLRYACAVCDAARVTRQDLPADIAAQLGGTSPGMLPDDERGRIVA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEE
ALTAHRWRPDAAAQALGISRATLYRRIAKHRIVAPHRA
EEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PYAVPQAQHADRVLGALAGRLPAPAESTRLVSSWQRSLERYCLDPASSIGPRVLTAAEL
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHH
REVRDKEEAFLRASGQCLTRLHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHHHHHHCCE
IGSCWSESEEGTCGVANVLTDLAPITVHKTDHFRAAFTTLTCSAAPIFSPGGELIGVLDA
EECCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHEEHHEEEECCCCCCCCCCCEEEEEEH
SAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCEEECCCCEEEEE
DECGNIVAANRQARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRLRATGAPLYA
HHCCCEEECCCHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHEEEEECCCCCHHH
RLRAPLRRPGREPGTASRRPGTAQRHVGALTPFLHSNDAHIAQQAELALRVASKRLPILV
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCEEE
LGETGAGKEVFARAIHDAGARRARPFVAVNCGALPEALIESELFGYAAGAFTGARKHGAR
EECCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GKIALADGGTLFLDEIGDMPLALQTRLLRVLSDGEVVPLGSDTPVRVDLDVICATHRDLA
CEEEEECCCEEEEHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEHHEEEHHHHHHH
RMVADGTFREDLYYRLSGATFELPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQ
HHHHCCCHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
LAAYPWPGNVRQLRNVLRYACAVCDAARVTRQDLPADIAAQLGGTSPGMLPDDERGRIVA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEE
ALTAHRWRPDAAAQALGISRATLYRRIAKHRIVAPHRA
EEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]