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The map label for this gene is kdgR [H]

Identifier: 78066495

GI number: 78066495

Start: 2059273

End: 2060316

Strand: Reverse

Name: kdgR [H]

Synonym: Bcep18194_A5026

Alternate gene names: 78066495

Gene position: 2060316-2059273 (Counterclockwise)

Preceding gene: 78066496

Following gene: 78066494

Centisome position: 55.77

GC content: 69.25

Gene sequence:

>1044_bases
GTGACCGATTCGCAACCAACCACGACGCGTCCGGCGACGATCAGCGATGTCGCGCGCGAAGCCGGCACGGGCAAAACCAG
CGTATCGCGCTACCTGAACGGCGAGACGCACGTGCTGTCCACCGATCTGCGCCAGCGTATCGAAGCGGCAATCGCACGGC
TCAACTACCGGCCGAACCAGATGGCGCGCGGGCTCAAGCGCGGCCGCAACCGCTTGCTCGGCATGCTCGCGGCCGACCTG
ACCAATCCCTATACCGTCGAAGTGCTGCAGGGCGTCGAGGCCGCATGCCATGCGCTCGGCTACATGCCGCTGATCTGTCA
CGCGGCAAACGAAGTCGAGATGGAGCGCCGCTTCCTGCAGCTGCTCACGACCTACCGCGTCGAAGGGCTGATCGTCAACG
CGCTCGGCGCCGATGAGGACGTGCTGCGCCCGTTGCGCGGGGCCGGCATCCCGGCCGTGCTCGTCGACCGGACGGTCGAA
GGCTTCGAGGCCGACCTGATCGGTCTCGACAACGCCGACGCGATCGAGACGGCCGTCGCACACCTGGTCGAACACGGTTT
CGACGCGATCCATTTCGTCGTGCAGCCGTTCGAGCGCGTCAGCTCGCGGCGCCTGCGCGAAGCCGCGTTCCGCGTGGCAC
TGGCGGCGCGCGGGCTGACGGTGCCGTCGACGGTCGTGCTCGACCTGAACGAGCCCGACGGGGTCACGGCGGCGCTGGCC
GACATCGATGCCCGCATCGACGACGCGGCACGGCGCGGCGTGCGCGCGGCGCTGTTCGCCGCGAACGCGCCGGTCGCACT
CGCGATCGCGCGCCACCTGCGCGCGCGTTTCGGCACCGCCTGGCAGCAGAGGGCGGCACTGCTGTCGATCGACGATCCGG
AATGGGCCGAGCTGATCGGGATCACGACGATCCGCCAGCCGACCTACGAAATCGGCTACAAGGCCGTCGAATTCGTGCAC
GAGCGGATCGACGGCGCAGCGGGCGACGTACGCGTCTCGCTGTTGCCGGGCGAGCTGGTTGCGCGCGCGTCGACCGCAAG
CTGA

Upstream 100 bases:

>100_bases
CGCTGACCGACAGGAGATTCCACCGGGTGGCTTACGTTTCCAACAACAAAGGTCCGTCTGCTCACAAAGCGGCGCGGATC
GTACGTCGCGAGGCACGACA

Downstream 100 bases:

>100_bases
GTATCATTCGGGGCACGCAGCGCGTCAGGTGCGCTGCCCCGAACAAGGAAATACATGACTGTCGCCCCCATCACGCTGGC
GGTGCTGATCGCCGCCACGC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTDSQPTTTRPATISDVAREAGTGKTSVSRYLNGETHVLSTDLRQRIEAAIARLNYRPNQMARGLKRGRNRLLGMLAADL
TNPYTVEVLQGVEAACHALGYMPLICHAANEVEMERRFLQLLTTYRVEGLIVNALGADEDVLRPLRGAGIPAVLVDRTVE
GFEADLIGLDNADAIETAVAHLVEHGFDAIHFVVQPFERVSSRRLREAAFRVALAARGLTVPSTVVLDLNEPDGVTAALA
DIDARIDDAARRGVRAALFAANAPVALAIARHLRARFGTAWQQRAALLSIDDPEWAELIGITTIRQPTYEIGYKAVEFVH
ERIDGAAGDVRVSLLPGELVARASTAS

Sequences:

>Translated_347_residues
MTDSQPTTTRPATISDVAREAGTGKTSVSRYLNGETHVLSTDLRQRIEAAIARLNYRPNQMARGLKRGRNRLLGMLAADL
TNPYTVEVLQGVEAACHALGYMPLICHAANEVEMERRFLQLLTTYRVEGLIVNALGADEDVLRPLRGAGIPAVLVDRTVE
GFEADLIGLDNADAIETAVAHLVEHGFDAIHFVVQPFERVSSRRLREAAFRVALAARGLTVPSTVVLDLNEPDGVTAALA
DIDARIDDAARRGVRAALFAANAPVALAIARHLRARFGTAWQQRAALLSIDDPEWAELIGITTIRQPTYEIGYKAVEFVH
ERIDGAAGDVRVSLLPGELVARASTAS
>Mature_346_residues
TDSQPTTTRPATISDVAREAGTGKTSVSRYLNGETHVLSTDLRQRIEAAIARLNYRPNQMARGLKRGRNRLLGMLAADLT
NPYTVEVLQGVEAACHALGYMPLICHAANEVEMERRFLQLLTTYRVEGLIVNALGADEDVLRPLRGAGIPAVLVDRTVEG
FEADLIGLDNADAIETAVAHLVEHGFDAIHFVVQPFERVSSRRLREAAFRVALAARGLTVPSTVVLDLNEPDGVTAALAD
IDARIDDAARRGVRAALFAANAPVALAIARHLRARFGTAWQQRAALLSIDDPEWAELIGITTIRQPTYEIGYKAVEFVHE
RIDGAAGDVRVSLLPGELVARASTAS

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=29.153605015674, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=28.0757097791798, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790369, Length=344, Percent_Identity=25, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788474, Length=323, Percent_Identity=26.9349845201238, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994940, Length=221, Percent_Identity=30.316742081448, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789202, Length=222, Percent_Identity=28.8288288288288, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787906, Length=187, Percent_Identity=28.8770053475936, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786540, Length=342, Percent_Identity=27.1929824561404, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787580, Length=324, Percent_Identity=26.8518518518519, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790689, Length=208, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789068, Length=313, Percent_Identity=23.961661341853, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786268, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790715, Length=174, Percent_Identity=28.1609195402299, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37597; Mature: 37466

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSQPTTTRPATISDVAREAGTGKTSVSRYLNGETHVLSTDLRQRIEAAIARLNYRPNQ
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHH
MARGLKRGRNRLLGMLAADLTNPYTVEVLQGVEAACHALGYMPLICHAANEVEMERRFLQ
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHH
LLTTYRVEGLIVNALGADEDVLRPLRGAGIPAVLVDRTVEGFEADLIGLDNADAIETAVA
HHHHHHHHHEEEECCCCCHHHHHHHHCCCCCEEEHHCCCCCCCCCEECCCCCHHHHHHHH
HLVEHGFDAIHFVVQPFERVSSRRLREAAFRVALAARGLTVPSTVVLDLNEPDGVTAALA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
DIDARIDDAARRGVRAALFAANAPVALAIARHLRARFGTAWQQRAALLSIDDPEWAELIG
HHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHCCCEEECCCCHHHHHHH
ITTIRQPTYEIGYKAVEFVHERIDGAAGDVRVSLLPGELVARASTAS
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCC
>Mature Secondary Structure 
TDSQPTTTRPATISDVAREAGTGKTSVSRYLNGETHVLSTDLRQRIEAAIARLNYRPNQ
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHH
MARGLKRGRNRLLGMLAADLTNPYTVEVLQGVEAACHALGYMPLICHAANEVEMERRFLQ
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHH
LLTTYRVEGLIVNALGADEDVLRPLRGAGIPAVLVDRTVEGFEADLIGLDNADAIETAVA
HHHHHHHHHEEEECCCCCHHHHHHHHCCCCCEEEHHCCCCCCCCCEECCCCCHHHHHHHH
HLVEHGFDAIHFVVQPFERVSSRRLREAAFRVALAARGLTVPSTVVLDLNEPDGVTAALA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
DIDARIDDAARRGVRAALFAANAPVALAIARHLRARFGTAWQQRAALLSIDDPEWAELIG
HHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHCCCEEECCCCHHHHHHH
ITTIRQPTYEIGYKAVEFVHERIDGAAGDVRVSLLPGELVARASTAS
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]