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The map label for this gene is yyaJ [H]

Identifier: 78066330

GI number: 78066330

Start: 1877430

End: 1878893

Strand: Reverse

Name: yyaJ [H]

Synonym: Bcep18194_A4860

Alternate gene names: 78066330

Gene position: 1878893-1877430 (Counterclockwise)

Preceding gene: 78066331

Following gene: 78066321

Centisome position: 50.86

GC content: 66.33

Gene sequence:

>1464_bases
ATGAACAGCCATTCCCTCGATCTCGGCGGCAACGCGGGCGGACCCGCGTCCGCACGACCGCCGGCCGCTGCCGCCGGCGT
CGACGCCGATGCGTCGGCCCTCCCCGCCCGCCGCGTCACGCTCGGCGATTTCATGGACGACCTGCCCGTCGGCGCGTTGC
ACCGGTTCGTCGTCTGGGTGATCGGCATCGGGCTGTTCTTCGACATGTACGAGATCTTCCTCGTCAGCACGATCGGTTCC
GCGTTGCAGAACGAATACGGGCTGAGCCGGCAGAGCACCGATTTCAAGCTGCTGCTCGCATCGGCATTCATCGGCATGTT
CGTCGGCGCGATGTGCCTCGGCAGCCTCGCCGACCGCATCGGCCGGCGCAAGGCGTTCCTGCTGACGCTCACGTGGTACA
GCGCGTTCTCGCTGGTCGGTGCGTTTTCGGTGAATGCCGACATGCTCGTCGCATGCCGGTTCCTGACCGGCATCGGCGTC
GGCGCGATCTATCCGGTTGCCGACAGCTTCCTGTCCGAGATCCTGCCGAAGGAAAAGCGCGGCAGGCTCGCTGCGTGGGC
CTATACGACTTCCTATGTCGCGGTGCCGCTCGTCGGGTTCCTCGCGCTGTGGCTGAACCCGCTGCATGTGGGTGGCGTGG
CCGGCTGGCGCATCATCCTCGCGATCGGCAGCCTCGGCGCCGTGTACGTGATGCTCGTCCAGCACCGTTTGCCGGAGAGC
CCGCGCTGGCTGCTCGCACAAGGGCGCACCGCTGACGCGCATGCGGCACTGCGGCGCTTCGCGGAAGGCACCGGCGTGCG
CGTGCCCGAGCAGTTCGCGGAACCGGTCGAGCCGCAACGGCCGCTCGGGCTCGGCGAGCGTATCGCACTGCTGCGGCGCG
AACCGTACGGCGCGCGCTACCTGATGCTCGCGATCTTTCACCTGTTCCAGGGCTTCGGCTATTACGGCTTCGGCACGCTG
GCCGGCACGGTCGTGAAGAGCCGCGGCTTCGACGTGACGGACAGCACGCTGTTCATCGCGCTGTCGTTCATCGGCTATCC
GGTCGGCTCGCTGCTGTCGATTCCGCTGCTCAACCGGATCGAGCGGCGCACGCTCGTGATCGTGTCGATCCTGTCGATCG
CCGTGTTCGGGCTGTGCTTCGCGTATTCGGGCAATACCGTGCTGATCGTCGGCTTCGGGTTCCTCACGACCTGCGCGTCG
AACGTGTTCAGCAACGCGTATCACGTGTATCAGGCGGAGATTTTCCCGGCGCGTGTGCGTTCGACGGCGATCGGCAGTAC
CTATGCGCTGTCGCGCATCGTCAGCGGCGTGCTGCCGTTCGTGTTGTTGCCGGTACTTGCCAGTTATGGCGCGGGTGCGA
TGTTCGGGGTGATCTCGGTCGCGCTGGGTATCGTCGCGGTCACGTTGCGCGTGCTCGGGCCGCTGACTACGCGGCGCAGC
CAGGATGAGATCAATCCGGTTTGA

Upstream 100 bases:

>100_bases
GCCCTGCGGTGCCTGCCGCCACGTCGTGCGACCGGATGCATCGCGCCGGTCGCGAACGGCCGGGCCTTGCGCCACGGCGT
ATCGATAATCAGGAGACACG

Downstream 100 bases:

>100_bases
GCGGTTGCTGATGAGGGGGCGCGGGGTCGCGTTTCCTCATCATTATTGAGCGGTCATTGCCACGCGACTAGGCCGCGGTC
GCAACCACGACGGGCTGGTA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MNSHSLDLGGNAGGPASARPPAAAAGVDADASALPARRVTLGDFMDDLPVGALHRFVVWVIGIGLFFDMYEIFLVSTIGS
ALQNEYGLSRQSTDFKLLLASAFIGMFVGAMCLGSLADRIGRRKAFLLTLTWYSAFSLVGAFSVNADMLVACRFLTGIGV
GAIYPVADSFLSEILPKEKRGRLAAWAYTTSYVAVPLVGFLALWLNPLHVGGVAGWRIILAIGSLGAVYVMLVQHRLPES
PRWLLAQGRTADAHAALRRFAEGTGVRVPEQFAEPVEPQRPLGLGERIALLRREPYGARYLMLAIFHLFQGFGYYGFGTL
AGTVVKSRGFDVTDSTLFIALSFIGYPVGSLLSIPLLNRIERRTLVIVSILSIAVFGLCFAYSGNTVLIVGFGFLTTCAS
NVFSNAYHVYQAEIFPARVRSTAIGSTYALSRIVSGVLPFVLLPVLASYGAGAMFGVISVALGIVAVTLRVLGPLTTRRS
QDEINPV

Sequences:

>Translated_487_residues
MNSHSLDLGGNAGGPASARPPAAAAGVDADASALPARRVTLGDFMDDLPVGALHRFVVWVIGIGLFFDMYEIFLVSTIGS
ALQNEYGLSRQSTDFKLLLASAFIGMFVGAMCLGSLADRIGRRKAFLLTLTWYSAFSLVGAFSVNADMLVACRFLTGIGV
GAIYPVADSFLSEILPKEKRGRLAAWAYTTSYVAVPLVGFLALWLNPLHVGGVAGWRIILAIGSLGAVYVMLVQHRLPES
PRWLLAQGRTADAHAALRRFAEGTGVRVPEQFAEPVEPQRPLGLGERIALLRREPYGARYLMLAIFHLFQGFGYYGFGTL
AGTVVKSRGFDVTDSTLFIALSFIGYPVGSLLSIPLLNRIERRTLVIVSILSIAVFGLCFAYSGNTVLIVGFGFLTTCAS
NVFSNAYHVYQAEIFPARVRSTAIGSTYALSRIVSGVLPFVLLPVLASYGAGAMFGVISVALGIVAVTLRVLGPLTTRRS
QDEINPV
>Mature_487_residues
MNSHSLDLGGNAGGPASARPPAAAAGVDADASALPARRVTLGDFMDDLPVGALHRFVVWVIGIGLFFDMYEIFLVSTIGS
ALQNEYGLSRQSTDFKLLLASAFIGMFVGAMCLGSLADRIGRRKAFLLTLTWYSAFSLVGAFSVNADMLVACRFLTGIGV
GAIYPVADSFLSEILPKEKRGRLAAWAYTTSYVAVPLVGFLALWLNPLHVGGVAGWRIILAIGSLGAVYVMLVQHRLPES
PRWLLAQGRTADAHAALRRFAEGTGVRVPEQFAEPVEPQRPLGLGERIALLRREPYGARYLMLAIFHLFQGFGYYGFGTL
AGTVVKSRGFDVTDSTLFIALSFIGYPVGSLLSIPLLNRIERRTLVIVSILSIAVFGLCFAYSGNTVLIVGFGFLTTCAS
NVFSNAYHVYQAEIFPARVRSTAIGSTYALSRIVSGVLPFVLLPVLASYGAGAMFGVISVALGIVAVTLRVLGPLTTRRS
QDEINPV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=404, Percent_Identity=23.5148514851485, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI213021148, Length=488, Percent_Identity=24.3852459016393, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4507005, Length=380, Percent_Identity=26.0526315789474, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI262399383, Length=302, Percent_Identity=24.1721854304636, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI24497490, Length=412, Percent_Identity=24.0291262135922, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI166064021, Length=402, Percent_Identity=25.1243781094527, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI73695465, Length=268, Percent_Identity=24.6268656716418, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI216548223, Length=171, Percent_Identity=29.2397660818713, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI24308167, Length=427, Percent_Identity=22.9508196721311, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI24497476, Length=425, Percent_Identity=24, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI166197673, Length=371, Percent_Identity=26.1455525606469, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI20070188, Length=425, Percent_Identity=24, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI302148518, Length=243, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI90669191, Length=406, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24497497, Length=390, Percent_Identity=27.1794871794872, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI296080719, Length=391, Percent_Identity=24.8081841432225, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI24497499, Length=391, Percent_Identity=24.8081841432225, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI296080721, Length=391, Percent_Identity=24.8081841432225, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI33457322, Length=302, Percent_Identity=25.1655629139073, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI24497478, Length=375, Percent_Identity=23.2, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI24497480, Length=375, Percent_Identity=23.2, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788074, Length=365, Percent_Identity=29.5890410958904, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1786229, Length=415, Percent_Identity=27.4698795180723, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87082159, Length=411, Percent_Identity=29.1970802919708, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788068, Length=475, Percent_Identity=26.1052631578947, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1789207, Length=379, Percent_Identity=23.7467018469657, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790463, Length=373, Percent_Identity=25.201072386059, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789312, Length=196, Percent_Identity=27.0408163265306, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082231, Length=181, Percent_Identity=24.3093922651934, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082404, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565976, Length=380, Percent_Identity=25.7894736842105, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32564663, Length=493, Percent_Identity=23.7322515212982, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988651, Length=332, Percent_Identity=24.6987951807229, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565921, Length=351, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71986689, Length=382, Percent_Identity=23.0366492146597, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202825, Length=382, Percent_Identity=23.0366492146597, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565978, Length=356, Percent_Identity=23.876404494382, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319718, Length=171, Percent_Identity=28.6549707602339, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24640198, Length=234, Percent_Identity=29.4871794871795, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640196, Length=234, Percent_Identity=29.4871794871795, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640200, Length=234, Percent_Identity=29.4871794871795, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24652795, Length=398, Percent_Identity=24.6231155778894, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24652793, Length=398, Percent_Identity=25.1256281407035, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20130083, Length=407, Percent_Identity=24.0786240786241, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649622, Length=397, Percent_Identity=21.4105793450882, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922616, Length=414, Percent_Identity=24.1545893719807, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161077756, Length=236, Percent_Identity=28.3898305084746, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649618, Length=353, Percent_Identity=22.9461756373938, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52188; Mature: 52188

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHSLDLGGNAGGPASARPPAAAAGVDADASALPARRVTLGDFMDDLPVGALHRFVVWV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHH
IGIGLFFDMYEIFLVSTIGSALQNEYGLSRQSTDFKLLLASAFIGMFVGAMCLGSLADRI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRRKAFLLTLTWYSAFSLVGAFSVNADMLVACRFLTGIGVGAIYPVADSFLSEILPKEKR
CCCEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHC
GRLAAWAYTTSYVAVPLVGFLALWLNPLHVGGVAGWRIILAIGSLGAVYVMLVQHRLPES
CCEEEEEHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRWLLAQGRTADAHAALRRFAEGTGVRVPEQFAEPVEPQRPLGLGERIALLRREPYGARY
CCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHH
LMLAIFHLFQGFGYYGFGTLAGTVVKSRGFDVTDSTLFIALSFIGYPVGSLLSIPLLNRI
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
ERRTLVIVSILSIAVFGLCFAYSGNTVLIVGFGFLTTCASNVFSNAYHVYQAEIFPARVR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
STAIGSTYALSRIVSGVLPFVLLPVLASYGAGAMFGVISVALGIVAVTLRVLGPLTTRRS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QDEINPV
CCCCCCC
>Mature Secondary Structure
MNSHSLDLGGNAGGPASARPPAAAAGVDADASALPARRVTLGDFMDDLPVGALHRFVVWV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHH
IGIGLFFDMYEIFLVSTIGSALQNEYGLSRQSTDFKLLLASAFIGMFVGAMCLGSLADRI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRRKAFLLTLTWYSAFSLVGAFSVNADMLVACRFLTGIGVGAIYPVADSFLSEILPKEKR
CCCEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHC
GRLAAWAYTTSYVAVPLVGFLALWLNPLHVGGVAGWRIILAIGSLGAVYVMLVQHRLPES
CCEEEEEHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRWLLAQGRTADAHAALRRFAEGTGVRVPEQFAEPVEPQRPLGLGERIALLRREPYGARY
CCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHH
LMLAIFHLFQGFGYYGFGTLAGTVVKSRGFDVTDSTLFIALSFIGYPVGSLLSIPLLNRI
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
ERRTLVIVSILSIAVFGLCFAYSGNTVLIVGFGFLTTCASNVFSNAYHVYQAEIFPARVR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
STAIGSTYALSRIVSGVLPFVLLPVLASYGAGAMFGVISVALGIVAVTLRVLGPLTTRRS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QDEINPV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]