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The map label for this gene is cobI [H]

Identifier: 78066292

GI number: 78066292

Start: 1839050

End: 1839784

Strand: Reverse

Name: cobI [H]

Synonym: Bcep18194_A4822

Alternate gene names: 78066292

Gene position: 1839784-1839050 (Counterclockwise)

Preceding gene: 78066293

Following gene: 78066291

Centisome position: 49.8

GC content: 67.48

Gene sequence:

>735_bases
ATGACGACCGCGCGCGGACGCCTGTTCGGGGTCGGCGTCGGCCCCGGCGATCCTGAACTGATGACGATCAAGGCGCTGCG
CGTGCTGCAGGCCGCGCCCGTGGTCGCGTATTTCGTCGCAAAGGGCAAGAAAGGCAATGCGTACGGCATCGTCGAAGCGC
ACCTGCGGGACGGGCAAACGCAACTGCCGCTCGTCTATCCGGTGACGACCGAGGCGCTGCCGCCGCCGCTATGCTACGAG
ACGGTGATCGCCGACTTCTACGATACGGCCGCCGAGATCGTTGCCGCGCACCTCGATGCCGGCCGCGACGTCGCGGTGAT
CTGCGAAGGCGACCCGTTCTTCTACGGCTCGTACATGTACCTGCACGACCGCCTCGCGCCGCGCTACGACACCGAGGTGA
TCCCCGGCGTATGCGCGATGCTCGGCGGCACCGCCGTGCTCGGCCAGCCGCTCGTCTATCGCAACCAGAGTTTGTCGGTG
CTGTCGGGCGTGCTGCCCGAGCACGAACTGCGCGAGCGGCTCGCGCGAGCCGACGCGGCCGTCGTGATGAAGCTCGGCCG
CAACTTCGACAAGGTGCGGCGCGTGCTCGACGAGCTGGGGCTCACGAAGCGCGCGCTGTATGTCGAGCGCGCGACGATGG
CGAGCCAGCGCATCGTGCCGCTCGACGAAGTCGATCCGATGGCGTCGCCGTATTTCTCGCTGCTCGTCGTGCCGGGGGAA
AAATGGCAAGGATGA

Upstream 100 bases:

>100_bases
ATGCCGACAGCCGCGGCGTGCCGTACGTCGCGCTGCTCGGCCGGCGTGGCGGCAGCGCGATGGCCGCTGCGGCGATCAAC
GCCCTCGCGACGGAGGTCGA

Downstream 100 bases:

>100_bases
CGACGCCGCCCGCCATCGTGATTCTCGGCGCGGGCGCGCTCGATACCGCGCGGCGCATCCAGACGCGCTATCCGGGTGCG
CTCGTGCATGGCCTCGCATC

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTTARGRLFGVGVGPGDPELMTIKALRVLQAAPVVAYFVAKGKKGNAYGIVEAHLRDGQTQLPLVYPVTTEALPPPLCYE
TVIADFYDTAAEIVAAHLDAGRDVAVICEGDPFFYGSYMYLHDRLAPRYDTEVIPGVCAMLGGTAVLGQPLVYRNQSLSV
LSGVLPEHELRERLARADAAVVMKLGRNFDKVRRVLDELGLTKRALYVERATMASQRIVPLDEVDPMASPYFSLLVVPGE
KWQG

Sequences:

>Translated_244_residues
MTTARGRLFGVGVGPGDPELMTIKALRVLQAAPVVAYFVAKGKKGNAYGIVEAHLRDGQTQLPLVYPVTTEALPPPLCYE
TVIADFYDTAAEIVAAHLDAGRDVAVICEGDPFFYGSYMYLHDRLAPRYDTEVIPGVCAMLGGTAVLGQPLVYRNQSLSV
LSGVLPEHELRERLARADAAVVMKLGRNFDKVRRVLDELGLTKRALYVERATMASQRIVPLDEVDPMASPYFSLLVVPGE
KWQG
>Mature_243_residues
TTARGRLFGVGVGPGDPELMTIKALRVLQAAPVVAYFVAKGKKGNAYGIVEAHLRDGQTQLPLVYPVTTEALPPPLCYET
VIADFYDTAAEIVAAHLDAGRDVAVICEGDPFFYGSYMYLHDRLAPRYDTEVIPGVCAMLGGTAVLGQPLVYRNQSLSVL
SGVLPEHELRERLARADAAVVMKLGRNFDKVRRVLDELGLTKRALYVERATMASQRIVPLDEVDPMASPYFSLLVVPGEK
WQG

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26635; Mature: 26504

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTARGRLFGVGVGPGDPELMTIKALRVLQAAPVVAYFVAKGKKGNAYGIVEAHLRDGQT
CCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCC
QLPLVYPVTTEALPPPLCYETVIADFYDTAAEIVAAHLDAGRDVAVICEGDPFFYGSYMY
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCEEE
LHDRLAPRYDTEVIPGVCAMLGGTAVLGQPLVYRNQSLSVLSGVLPEHELRERLARADAA
EECCCCCCCCCHHHHHHHHHHCCHHHHCCCEEECCCCHHHHHHCCCHHHHHHHHHHHHHH
VVMKLGRNFDKVRRVLDELGLTKRALYVERATMASQRIVPLDEVDPMASPYFSLLVVPGE
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCC
KWQG
CCCC
>Mature Secondary Structure 
TTARGRLFGVGVGPGDPELMTIKALRVLQAAPVVAYFVAKGKKGNAYGIVEAHLRDGQT
CCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCC
QLPLVYPVTTEALPPPLCYETVIADFYDTAAEIVAAHLDAGRDVAVICEGDPFFYGSYMY
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCEEE
LHDRLAPRYDTEVIPGVCAMLGGTAVLGQPLVYRNQSLSVLSGVLPEHELRERLARADAA
EECCCCCCCCCHHHHHHHHHHCCHHHHCCCEEECCCCHHHHHHCCCHHHHHHHHHHHHHH
VVMKLGRNFDKVRRVLDELGLTKRALYVERATMASQRIVPLDEVDPMASPYFSLLVVPGE
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCC
KWQG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]