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The map label for this gene is cobJ [H]

Identifier: 78066291

GI number: 78066291

Start: 1837323

End: 1839062

Strand: Reverse

Name: cobJ [H]

Synonym: Bcep18194_A4821

Alternate gene names: 78066291

Gene position: 1839062-1837323 (Counterclockwise)

Preceding gene: 78066292

Following gene: 78066289

Centisome position: 49.78

GC content: 70.69

Gene sequence:

>1740_bases
ATGGCAAGGATGACGACGCCGCCCGCCATCGTGATTCTCGGCGCGGGCGCGCTCGATACCGCGCGGCGCATCCAGACGCG
CTATCCGGGTGCGCTCGTGCATGGCCTCGCATCGCGCGTCGCGGCCGATGTGGCGTTCGACGATCTCGGCGCGCACCTGC
GTGAACTCTATGCACGCGGGCTGCCGATCGTCGCGCTGTGCGCGGCCGGCATCGTGATCCGCTGCATCGCCCCCGCGCTC
GCCGACAAGGGCGTCGAGCCGCCTGTGCTCGCGGTCGCGGAAGACGGCTCGGCGGTCGTACCGCTGCTCGGCGGGCTGAC
GGGCGTCAACGTGATGGCGCGAGAAATCGCCGCATGCGTCGGCGTGGCTCCCGCGATCACGACGAGCGGCGAACTGCGCT
TCGGCGCGTGCGTGCTCAATCCGCCGGAAGGCTATGCGCTCGCCGATCTTGCACAGGGCAAGCGCTTCGTATCCGATCTG
CTCGCGGGCGCGTCGACGCGCATCGACGGCGCGGCGCCGTGGCTCGACGACGTCGCGTTGCCGCGCGACGACGCGGCTGC
GCATGCGATCCGCGTGACTCCCGATGCATGGCGCGGTACGCGCGACGAGCTCGTGATTCATCCGCGCAGCGTGGTAGTGG
GCATCGATGCGCAGGCTATCCAAGGCAATGAAGCACTCGCTGCGCGCATCGACGCCACGCTCGATGCGCAAGGTCTCGCG
CGGCTGGCGCTCGCGGCTATCGTTGCACCCGCATCGGCAATCGGTGATGACGTGCTGGAAGAAGCGGCGCAAACGCTCGA
CGTTCCGCTGCGCTTCATCGATGCCGATGTCGATGTCAGCGATAGTAACGGCGACGTACCCACCGACGCCGCCGTCCTGC
TCGGCGGCGCGTTGCGTGTCGCGCACACACTGCGCGCCACGACGAACGGCATCGCATGCGCGGTTGCGTCGCATCCGGTC
GATCCCGCCACGCTCGGCCGTGCACGCGGCCGCCTGACGGTGCTCGGCCTCGGCCCGGGCGGTGCTGCATGGCTTACCCC
GGCCGCGCGCGCCGCGCTCGCGGAAGCGACCGACATCCTCGGCTACACGACCTACGTGAACATGGCCGGCCCGTTCCGTG
GCGACCAGCGCGTGCACGGCACTGACAATCGCGAGGAAATGCAGCGCGCGCGCCATGCGTTCGAGCTCGCGGCCGAGGGC
CGGCGCGTCGCGGTCGTGTCGTCGGGTGACCCGGGCGTGTTCGCGATGGCCGCGGCCGTGCTCGAAGCGCTCGATGAAGC
GCGCGATCCGCACTGGGCGGCGGTCGACCTGCGCGTGGAGCCCGGTATCTCGGCGTCGCTCGCGACGGCCGCGCAGGCCG
GTGCGCCGCTCGGTCACGACTTCTGTGCGATCTCGCTGTCGGACAACCTGAAGCCGTGGGACGTGATCGAGACACGCCTG
CGGCATGCGGCGCAGGCCGACCTGGTGATGGCGTTCTACAACCCGATCTCGCGCGCGCGGCCTTGGCAGCTCGATCGCGC
GCTCGACGTCGTGCGCGCGCACCGCACGGCCGAGACGGTGGTCGTGCTCGGCCGCGACATCGGCCGGCCGGGCGCAACGC
TCACGACGACGACGCTCGGCGCGCTGCGCAGCGACCAGGTCGACATGCGCACGATGGTGATCGTCGGCTCGTCGACGACG
CGGCGCTTCGCGATCGGCAACGCACGCGAGTGGGTCTATACGCCGCGCTGGTATCGCTGA

Upstream 100 bases:

>100_bases
TCGAGCGCGCGACGATGGCGAGCCAGCGCATCGTGCCGCTCGACGAAGTCGATCCGATGGCGTCGCCGTATTTCTCGCTG
CTCGTCGTGCCGGGGGAAAA

Downstream 100 bases:

>100_bases
ACCCGGTCAGCGCGTCGGCGTGACGGTGCGTGCGTCGGCCTGCGCGGTGCCGGCTGCGCTGCCCGCGTGCCAGAACCGGT
ACACGAGCACGCCGACGATG

Product: precorrin-3 methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MARMTTPPAIVILGAGALDTARRIQTRYPGALVHGLASRVAADVAFDDLGAHLRELYARGLPIVALCAAGIVIRCIAPAL
ADKGVEPPVLAVAEDGSAVVPLLGGLTGVNVMAREIAACVGVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDL
LAGASTRIDGAAPWLDDVALPRDDAAAHAIRVTPDAWRGTRDELVIHPRSVVVGIDAQAIQGNEALAARIDATLDAQGLA
RLALAAIVAPASAIGDDVLEEAAQTLDVPLRFIDADVDVSDSNGDVPTDAAVLLGGALRVAHTLRATTNGIACAVASHPV
DPATLGRARGRLTVLGLGPGGAAWLTPAARAALAEATDILGYTTYVNMAGPFRGDQRVHGTDNREEMQRARHAFELAAEG
RRVAVVSSGDPGVFAMAAAVLEALDEARDPHWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRL
RHAAQADLVMAFYNPISRARPWQLDRALDVVRAHRTAETVVVLGRDIGRPGATLTTTTLGALRSDQVDMRTMVIVGSSTT
RRFAIGNAREWVYTPRWYR

Sequences:

>Translated_579_residues
MARMTTPPAIVILGAGALDTARRIQTRYPGALVHGLASRVAADVAFDDLGAHLRELYARGLPIVALCAAGIVIRCIAPAL
ADKGVEPPVLAVAEDGSAVVPLLGGLTGVNVMAREIAACVGVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDL
LAGASTRIDGAAPWLDDVALPRDDAAAHAIRVTPDAWRGTRDELVIHPRSVVVGIDAQAIQGNEALAARIDATLDAQGLA
RLALAAIVAPASAIGDDVLEEAAQTLDVPLRFIDADVDVSDSNGDVPTDAAVLLGGALRVAHTLRATTNGIACAVASHPV
DPATLGRARGRLTVLGLGPGGAAWLTPAARAALAEATDILGYTTYVNMAGPFRGDQRVHGTDNREEMQRARHAFELAAEG
RRVAVVSSGDPGVFAMAAAVLEALDEARDPHWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRL
RHAAQADLVMAFYNPISRARPWQLDRALDVVRAHRTAETVVVLGRDIGRPGATLTTTTLGALRSDQVDMRTMVIVGSSTT
RRFAIGNAREWVYTPRWYR
>Mature_578_residues
ARMTTPPAIVILGAGALDTARRIQTRYPGALVHGLASRVAADVAFDDLGAHLRELYARGLPIVALCAAGIVIRCIAPALA
DKGVEPPVLAVAEDGSAVVPLLGGLTGVNVMAREIAACVGVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLL
AGASTRIDGAAPWLDDVALPRDDAAAHAIRVTPDAWRGTRDELVIHPRSVVVGIDAQAIQGNEALAARIDATLDAQGLAR
LALAAIVAPASAIGDDVLEEAAQTLDVPLRFIDADVDVSDSNGDVPTDAAVLLGGALRVAHTLRATTNGIACAVASHPVD
PATLGRARGRLTVLGLGPGGAAWLTPAARAALAEATDILGYTTYVNMAGPFRGDQRVHGTDNREEMQRARHAFELAAEGR
RVAVVSSGDPGVFAMAAAVLEALDEARDPHWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRLR
HAAQADLVMAFYNPISRARPWQLDRALDVVRAHRTAETVVVLGRDIGRPGATLTTTTLGALRSDQVDMRTMVIVGSSTTR
RFAIGNAREWVYTPRWYR

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 60525; Mature: 60393

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMTTPPAIVILGAGALDTARRIQTRYPGALVHGLASRVAADVAFDDLGAHLRELYARG
CCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPIVALCAAGIVIRCIAPALADKGVEPPVLAVAEDGSAVVPLLGGLTGVNVMAREIAACV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHH
GVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAGASTRIDGAAPWLDDVAL
CCCHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCC
PRDDAAAHAIRVTPDAWRGTRDELVIHPRSVVVGIDAQAIQGNEALAARIDATLDAQGLA
CCCCCCCEEEEECCHHHCCCCCCEEECCCEEEEECCHHEECCCCCEEEECCCCCCHHHHH
RLALAAIVAPASAIGDDVLEEAAQTLDVPLRFIDADVDVSDSNGDVPTDAAVLLGGALRV
HHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCCCCCCHHHHHHHHHHH
AHTLRATTNGIACAVASHPVDPATLGRARGRLTVLGLGPGGAAWLTPAARAALAEATDIL
HHHHHHCCCCEEEEEECCCCCHHHHHCCCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHH
GYTTYVNMAGPFRGDQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGDPGVFAMAAAV
EEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
LEALDEARDPHWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRL
HHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHH
RHAAQADLVMAFYNPISRARPWQLDRALDVVRAHRTAETVVVLGRDIGRPGATLTTTTLG
HHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHH
ALRSDQVDMRTMVIVGSSTTRRFAIGNAREWVYTPRWYR
HHCCCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCCC
>Mature Secondary Structure 
ARMTTPPAIVILGAGALDTARRIQTRYPGALVHGLASRVAADVAFDDLGAHLRELYARG
CCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPIVALCAAGIVIRCIAPALADKGVEPPVLAVAEDGSAVVPLLGGLTGVNVMAREIAACV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHH
GVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAGASTRIDGAAPWLDDVAL
CCCHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCC
PRDDAAAHAIRVTPDAWRGTRDELVIHPRSVVVGIDAQAIQGNEALAARIDATLDAQGLA
CCCCCCCEEEEECCHHHCCCCCCEEECCCEEEEECCHHEECCCCCEEEECCCCCCHHHHH
RLALAAIVAPASAIGDDVLEEAAQTLDVPLRFIDADVDVSDSNGDVPTDAAVLLGGALRV
HHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCCCCCCHHHHHHHHHHH
AHTLRATTNGIACAVASHPVDPATLGRARGRLTVLGLGPGGAAWLTPAARAALAEATDIL
HHHHHHCCCCEEEEEECCCCCHHHHHCCCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHH
GYTTYVNMAGPFRGDQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGDPGVFAMAAAV
EEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
LEALDEARDPHWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRL
HHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHH
RHAAQADLVMAFYNPISRARPWQLDRALDVVRAHRTAETVVVLGRDIGRPGATLTTTTLG
HHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHH
ALRSDQVDMRTMVIVGSSTTRRFAIGNAREWVYTPRWYR
HHCCCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]