Click here to switch to the map view.

The map label for this gene is marR [H]

Identifier: 78066157

GI number: 78066157

Start: 1682499

End: 1682984

Strand: Direct

Name: marR [H]

Synonym: Bcep18194_A4687

Alternate gene names: 78066157

Gene position: 1682499-1682984 (Clockwise)

Preceding gene: 78066156

Following gene: 78066158

Centisome position: 45.55

GC content: 61.11

Gene sequence:

>486_bases
ATGTCGCAATTATTGTGTGGGTCAATAAATTGCGACTCAGCGAGCCCGATGGAACACTACACGCCGAAGAATTTCCTGCA
CACCGAAAGCGTGGGGTTCATGCTCGTGAAGGCGCGCAATCTGATCACGTCCGAGATGGATGCGGCGTTGAAGGATCTCG
ATATCACGGCGCAGCAAATGGGCGTCCTGCTGTCCCTGCGTACCGGCATTGCGGCGACGCCGTTCGAATTGTCGAAGCTG
CTCGGCGTCGACACCGGGCTGATGACGCGCGTGCTCGACAAACTGGAGGGCAAGGGGCTCGTCGAGCGGTCGCGCAGCGT
GAGCGATCGGCGGGTGGTGAACCTCGCGCTGACCGAAGCGGGGCAGGCGGTGGCCGCGCAGATTCCGGAGATCGCGCCGA
AGGTGCTCAACGCCCGCTTGCGGAAATTCTCGAGGGCCGAGTTTGACGAACTGTCACGGCTGCTGCACAAGTTCATCGGC
GAGTAA

Upstream 100 bases:

>100_bases
AGGCCGGGCAAGGGCGTGGCAGCCGGGGCCGCGGCCGCCGGCGGGCACTGAGCCGGTGCAGGCGGTGCATGCAGGATTCC
GCGTGCCTTGAAAAATCGTG

Downstream 100 bases:

>100_bases
GCCGGGCGCCGTTTCCTGGCGCCGGAAATGAAAAAAGGCCGGCAAAAGCCGACCTTTTTTGAATACAGATGGTGCCCAGG
AGAGGACTCGAACCTCCACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSQLLCGSINCDSASPMEHYTPKNFLHTESVGFMLVKARNLITSEMDAALKDLDITAQQMGVLLSLRTGIAATPFELSKL
LGVDTGLMTRVLDKLEGKGLVERSRSVSDRRVVNLALTEAGQAVAAQIPEIAPKVLNARLRKFSRAEFDELSRLLHKFIG
E

Sequences:

>Translated_161_residues
MSQLLCGSINCDSASPMEHYTPKNFLHTESVGFMLVKARNLITSEMDAALKDLDITAQQMGVLLSLRTGIAATPFELSKL
LGVDTGLMTRVLDKLEGKGLVERSRSVSDRRVVNLALTEAGQAVAAQIPEIAPKVLNARLRKFSRAEFDELSRLLHKFIG
E
>Mature_160_residues
SQLLCGSINCDSASPMEHYTPKNFLHTESVGFMLVKARNLITSEMDAALKDLDITAQQMGVLLSLRTGIAATPFELSKLL
GVDTGLMTRVLDKLEGKGLVERSRSVSDRRVVNLALTEAGQAVAAQIPEIAPKVLNARLRKFSRAEFDELSRLLHKFIGE

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=115, Percent_Identity=40, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17656; Mature: 17525

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLLCGSINCDSASPMEHYTPKNFLHTESVGFMLVKARNLITSEMDAALKDLDITAQQM
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLLSLRTGIAATPFELSKLLGVDTGLMTRVLDKLEGKGLVERSRSVSDRRVVNLALTEA
HHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHH
GQAVAAQIPEIAPKVLNARLRKFSRAEFDELSRLLHKFIGE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQLLCGSINCDSASPMEHYTPKNFLHTESVGFMLVKARNLITSEMDAALKDLDITAQQM
CCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLLSLRTGIAATPFELSKLLGVDTGLMTRVLDKLEGKGLVERSRSVSDRRVVNLALTEA
HHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHH
GQAVAAQIPEIAPKVLNARLRKFSRAEFDELSRLLHKFIGE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]