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The map label for this gene is hfq [H]

Identifier: 78066141

GI number: 78066141

Start: 1662872

End: 1663450

Strand: Reverse

Name: hfq [H]

Synonym: Bcep18194_A4671

Alternate gene names: 78066141

Gene position: 1663450-1662872 (Counterclockwise)

Preceding gene: 78066143

Following gene: 78066127

Centisome position: 45.03

GC content: 69.95

Gene sequence:

>579_bases
ATGGCCAATCCCGCAGAATCCCATCCGCAAAACGACTTCATCAATTCGGCGCGCAAGGAACGTAAGCGCGTTGAAATCTA
TCTCGTCAACGGCATTCGTCTGACGGGGTGTATCGAGTCGTTCGACCAGTACCTGGTGATGCTGCGCACCCCCGTGGGTC
TGCAAGGCATCTACAAGCGCGCGATTTCCACGATCCAGCTCGACACGGGCGGCTCGCGCCCGGGCGGCAGCGGCCCCCGC
GGGCCGCGCACCGGCGGGCGCCCCGGCGGCCGTGAAGGCGGCGGTCACAGCCCGTACGGCTCGCACGGTGGCCCGCGCGA
ATCGCGCGGCGACGGCGGCTACGGCTCCCGCGAACCGCGTGAAGGCTATGGCTCGCGCGAACCGCGCGAGAGTTACGGCT
CGCGTGAGCCGCGCGAAGGCTACGGTGCCCCGCGCGAACCCCGTGAACCGCGCGAAAGCTACGGCGCGCCGCGCGACACC
GGCGACGCATCCGGCAACGCATCGTCGTCGGATTCCCGCGGCGGCAGCGGGCCGGTCATCGTGACGCGCCGCCGGCGAAT
CGTGCCGGACGGCCAGTAA

Upstream 100 bases:

>100_bases
CCCCGATTGAACAGGGTAGAATCCCGCCAAACACCTTGTGGACGAACACGCCACACACACGCACAACATATTCTCTGACG
CAGGCTCCTGCCGCACCTCA

Downstream 100 bases:

>100_bases
AACAAAAGGGCAAGCCAACCGGCTTGCCCTTTTTACTTGTGCGGCCGGCGCGGCATGTCGCCGCACCGCCGCCGGGTTCA
GCGTGCCGTCGTCGGCAGGC

Product: host factor Hfq

Products: NA

Alternate protein names: HF-1; Host factor-I protein; HF-I [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGSGPR
GPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPREGYGSREPRESYGSREPREGYGAPREPREPRESYGAPRDT
GDASGNASSSDSRGGSGPVIVTRRRRIVPDGQ

Sequences:

>Translated_192_residues
MANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGSGPR
GPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPREGYGSREPRESYGSREPREGYGAPREPREPRESYGAPRDT
GDASGNASSSDSRGGSGPVIVTRRRRIVPDGQ
>Mature_191_residues
ANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGSGPRG
PRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPREGYGSREPRESYGSREPREGYGAPREPREPRESYGAPRDTG
DASGNASSSDSRGGSGPVIVTRRRRIVPDGQ

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=56, Percent_Identity=55.3571428571429, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 20596; Mature: 20465

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKR
CCCCCCCCCCHHHHHHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
AISTIQLDTGGSRPGGSGPRGPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPR
HHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EGYGSREPRESYGSREPREGYGAPREPREPRESYGAPRDTGDASGNASSSDSRGGSGPVI
CCCCCCCCHHHHCCCCCHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
VTRRRRIVPDGQ
EECCCCCCCCCC
>Mature Secondary Structure 
ANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKR
CCCCCCCCCHHHHHHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
AISTIQLDTGGSRPGGSGPRGPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPR
HHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EGYGSREPRESYGSREPREGYGAPREPREPRESYGAPRDTGDASGNASSSDSRGGSGPVI
CCCCCCCCHHHHCCCCCHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
VTRRRRIVPDGQ
EECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]