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The map label for this gene is yafC [H]

Identifier: 78065393

GI number: 78065393

Start: 833309

End: 834292

Strand: Reverse

Name: yafC [H]

Synonym: Bcep18194_A3919

Alternate gene names: 78065393

Gene position: 834292-833309 (Counterclockwise)

Preceding gene: 78065395

Following gene: 78065392

Centisome position: 22.58

GC content: 71.44

Gene sequence:

>984_bases
ATGAACCAGATTCAGACCATGCGTGTATTCGTCTGCGTCGCCGAGCAGCAGAGCTTCCGGCGCGCGGCGCACCATCTCGG
CGTGTCCAATGCACTCGTCACGCGTTCGATCGCGATGCTCGAGGGCCACCTGAACACCCGGCTGATCCACCGCACCACGC
GGAACCTGTCGCTCACCGAGGCCGGCGTGCGCTACCTCGACGGGTGCCGGGCGCTGCTCGAGGAATTCGATCACCTCGAA
TCGTCCGTCGCGCATGCCGTGCGCGAACCGGCCGGTACGCTGCGCGTCGTCGCGTCGGGCCTGCTGTCGCCGCTCGCGCT
GACACCGCTCGTCAGCAGCTTCCGGCACCGCTACCCGGAGTTGCGCGTGCAGCTGACCGTCGCCGAGGGGCCGCTCGACG
TGCTCGATTCGGGTTACGACGTCGGCATCGTCACGGGCACCCGGCTCGACGGCAACCCGACGCTGATCGGCCACGCGCTC
GCACCGAACCCGTTCGTCGCGGTCGCGGCACCGGCCTATCTCGAGCGACGCGGCGAGCCGCGCCTGCCCGACGACCTGCC
GGGACACGACTGGGTCACGCTCGCGCCGCACCAGCATGCGCCCGCCTGGCAACTGGTCGGCCTCGACGGCGTCGCGCATT
CCGTCACGGTGCGCCCGGCCTGCACGGTCAACCAGCTCGCGCTCGTCCACGCGGCCGCGGTGGCCGGCGCGGGCATCGCG
GTGCTGCCCGAGCCGTGCGTCGCCAGCGCGCTCGCCAGCGGCACGCTCGTGCGGCTGATGGCCGGCTACCGGATCGACGA
CCCCGACACGCAGCTGTCGCTCGTGTACCCGAACCGCCAGTACGTGCCGGCCCGCACGCGCAGCTTCGTCGAGCACGCGC
TCGATCACTTCAGCGCGCAGCCGGCCCGCGAACGCACCGACTACGGCTTCATGCGGCCGTCGCGTGGGCCCGACCGCTCC
GACATCGTCACCGGGCTGCAGTAA

Upstream 100 bases:

>100_bases
GATACGATGTAAAAACTGGGGGCCGTGCGATGCGCTTTCGAGGTTGCGCGGCTTAAAACCACAACCATAATCAATCAACC
GGGCCAGAAATACGCAAGCC

Downstream 100 bases:

>100_bases
ACTGCGCGCGTCAGCCTTCGGAGGTGCAGCGTGCGCGTGATCCTGTTCAGCAGCCGGCAGTACGACGACGATTCGTTTGC
TGCCGCCAACCGGCAGTTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNQIQTMRVFVCVAEQQSFRRAAHHLGVSNALVTRSIAMLEGHLNTRLIHRTTRNLSLTEAGVRYLDGCRALLEEFDHLE
SSVAHAVREPAGTLRVVASGLLSPLALTPLVSSFRHRYPELRVQLTVAEGPLDVLDSGYDVGIVTGTRLDGNPTLIGHAL
APNPFVAVAAPAYLERRGEPRLPDDLPGHDWVTLAPHQHAPAWQLVGLDGVAHSVTVRPACTVNQLALVHAAAVAGAGIA
VLPEPCVASALASGTLVRLMAGYRIDDPDTQLSLVYPNRQYVPARTRSFVEHALDHFSAQPARERTDYGFMRPSRGPDRS
DIVTGLQ

Sequences:

>Translated_327_residues
MNQIQTMRVFVCVAEQQSFRRAAHHLGVSNALVTRSIAMLEGHLNTRLIHRTTRNLSLTEAGVRYLDGCRALLEEFDHLE
SSVAHAVREPAGTLRVVASGLLSPLALTPLVSSFRHRYPELRVQLTVAEGPLDVLDSGYDVGIVTGTRLDGNPTLIGHAL
APNPFVAVAAPAYLERRGEPRLPDDLPGHDWVTLAPHQHAPAWQLVGLDGVAHSVTVRPACTVNQLALVHAAAVAGAGIA
VLPEPCVASALASGTLVRLMAGYRIDDPDTQLSLVYPNRQYVPARTRSFVEHALDHFSAQPARERTDYGFMRPSRGPDRS
DIVTGLQ
>Mature_327_residues
MNQIQTMRVFVCVAEQQSFRRAAHHLGVSNALVTRSIAMLEGHLNTRLIHRTTRNLSLTEAGVRYLDGCRALLEEFDHLE
SSVAHAVREPAGTLRVVASGLLSPLALTPLVSSFRHRYPELRVQLTVAEGPLDVLDSGYDVGIVTGTRLDGNPTLIGHAL
APNPFVAVAAPAYLERRGEPRLPDDLPGHDWVTLAPHQHAPAWQLVGLDGVAHSVTVRPACTVNQLALVHAAAVAGAGIA
VLPEPCVASALASGTLVRLMAGYRIDDPDTQLSLVYPNRQYVPARTRSFVEHALDHFSAQPARERTDYGFMRPSRGPDRS
DIVTGLQ

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=31.986531986532, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=32.0819112627986, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=30.2013422818792, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=29.4314381270903, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=29.3918918918919, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=28.6689419795222, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789440, Length=260, Percent_Identity=28.8461538461538, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789173, Length=258, Percent_Identity=29.4573643410853, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693105, Length=174, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786713, Length=286, Percent_Identity=27.6223776223776, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788748, Length=165, Percent_Identity=29.6969696969697, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=303, Percent_Identity=24.7524752475248, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=260, Percent_Identity=25.3846153846154, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788706, Length=176, Percent_Identity=26.1363636363636, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35441; Mature: 35441

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIQTMRVFVCVAEQQSFRRAAHHLGVSNALVTRSIAMLEGHLNTRLIHRTTRNLSLTE
CCCHHEEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEEHHHCCCCCHHH
AGVRYLDGCRALLEEFDHLESSVAHAVREPAGTLRVVASGLLSPLALTPLVSSFRHRYPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LRVQLTVAEGPLDVLDSGYDVGIVTGTRLDGNPTLIGHALAPNPFVAVAAPAYLERRGEP
EEEEEEEECCCHHHHCCCCCEEEEECCEECCCCCEEEEECCCCCEEEEECCHHHHHCCCC
RLPDDLPGHDWVTLAPHQHAPAWQLVGLDGVAHSVTVRPACTVNQLALVHAAAVAGAGIA
CCCCCCCCCCEEEECCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEE
VLPEPCVASALASGTLVRLMAGYRIDDPDTQLSLVYPNRQYVPARTRSFVEHALDHFSAQ
ECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
PARERTDYGFMRPSRGPDRSDIVTGLQ
CCHHCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MNQIQTMRVFVCVAEQQSFRRAAHHLGVSNALVTRSIAMLEGHLNTRLIHRTTRNLSLTE
CCCHHEEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEEHHHCCCCCHHH
AGVRYLDGCRALLEEFDHLESSVAHAVREPAGTLRVVASGLLSPLALTPLVSSFRHRYPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LRVQLTVAEGPLDVLDSGYDVGIVTGTRLDGNPTLIGHALAPNPFVAVAAPAYLERRGEP
EEEEEEEECCCHHHHCCCCCEEEEECCEECCCCCEEEEECCCCCEEEEECCHHHHHCCCC
RLPDDLPGHDWVTLAPHQHAPAWQLVGLDGVAHSVTVRPACTVNQLALVHAAAVAGAGIA
CCCCCCCCCCEEEECCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEE
VLPEPCVASALASGTLVRLMAGYRIDDPDTQLSLVYPNRQYVPARTRSFVEHALDHFSAQ
ECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
PARERTDYGFMRPSRGPDRSDIVTGLQ
CCHHCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]