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The map label for this gene is dgk [H]

Identifier: 78065317

GI number: 78065317

Start: 750962

End: 751648

Strand: Reverse

Name: dgk [H]

Synonym: Bcep18194_A3843

Alternate gene names: 78065317

Gene position: 751648-750962 (Counterclockwise)

Preceding gene: 78065318

Following gene: 78065316

Centisome position: 20.35

GC content: 66.08

Gene sequence:

>687_bases
ATGACCCTGACTCCCCTTACCGTTACTGCGCCCGACCTGCGCGCCCCGCATCGCTATCTCGTGATCGAAGGCCCGATCGG
AGTCGGCAAGACGACGCTCGCGCGCCTGCTCGGCGAACGCTGGTCGATGCAGACGCTGCTCGAGCGCCCGCAGGACAACC
CGTTCCTCGAACGCTTCTATCGCGACACCGCGCGCTACGCGCTGCCCGTGCAGCTGTCGTTCGCGCTGCAGCGTGCGCAG
CAGGCGCGCGAGCTGATCGGTGCGCTCGAAACGGGCCGCCCGGTCATCGCCGATTTCATGCCGCAGAAAAACGACATCTT
CGCGCGGCTGAACCTTCCGGAAGACGAGTGGCAGCTCTACCGCTCGGTTGCGACGCACGTGGACGTGCCGCAGGCGCCGT
CGCCCGACCTCGTCGTCTATCTGCAGGCGAGCCCTGAAGTGCTGTTCTCGCGCATCCAGAAGCGCGGGCTGCCGATGGAG
CTGCAGATCAGCGACGCGTACCTGCGCTCGCTCGTCGACGCGTACAACGAATTCTTCTACCACTACGACCGCACGCCGGT
GCTGACGGTCGCCGCGGAACACCTGAACCCGCTGGATTCCCCCGAAGATCTCGCCCTGCTGGTCGAGCGCATCGAGACGA
TGCGCGGCCGCAAGGAATTCTTCGTCAAGGGCGAGACGACGCGCTGA

Upstream 100 bases:

>100_bases
CCGCCGTCGCTGATCAGCGGGTCGAGAAGGTGCAGACCTGCCAGTGCCTGATGCAGAAGGCGCTCGCTGCCAGCGAAGAC
GCCGACAAGAACCGCTGCCG

Downstream 100 bases:

>100_bases
CGCGTCCTCGCCTGTCGTTCTTCACCCATTCGAACCGGATTTCCCATGACCTATCTCCAGGAATCGAGCCGGCCTGCCGT
CACGGTGCCCAAGCTGCAGG

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTLTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLGERWSMQTLLERPQDNPFLERFYRDTARYALPVQLSFALQRAQ
QARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLYRSVATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPME
LQISDAYLRSLVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPEDLALLVERIETMRGRKEFFVKGETTR

Sequences:

>Translated_228_residues
MTLTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLGERWSMQTLLERPQDNPFLERFYRDTARYALPVQLSFALQRAQ
QARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLYRSVATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPME
LQISDAYLRSLVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPEDLALLVERIETMRGRKEFFVKGETTR
>Mature_227_residues
TLTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLGERWSMQTLLERPQDNPFLERFYRDTARYALPVQLSFALQRAQQ
ARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLYRSVATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPMEL
QISDAYLRSLVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPEDLALLVERIETMRGRKEFFVKGETTR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 26167; Mature: 26036

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLGERWSMQTLLERPQDNPFLERFY
CCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHH
RDTARYALPVQLSFALQRAQQARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLY
HHHHHEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
RSVATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPMELQISDAYLRSLVDAYNEFFY
HHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHH
HYDRTPVLTVAAEHLNPLDSPEDLALLVERIETMRGRKEFFVKGETTR
HCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHCCCHHEEEECCCCC
>Mature Secondary Structure 
TLTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLGERWSMQTLLERPQDNPFLERFY
CCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHH
RDTARYALPVQLSFALQRAQQARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLY
HHHHHEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
RSVATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPMELQISDAYLRSLVDAYNEFFY
HHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHH
HYDRTPVLTVAAEHLNPLDSPEDLALLVERIETMRGRKEFFVKGETTR
HCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHCCCHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]