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The map label for this gene is prc [C]

Identifier: 78065282

GI number: 78065282

Start: 700461

End: 701990

Strand: Reverse

Name: prc [C]

Synonym: Bcep18194_A3806

Alternate gene names: 78065282

Gene position: 701990-700461 (Counterclockwise)

Preceding gene: 78065283

Following gene: 78065277

Centisome position: 19.0

GC content: 69.93

Gene sequence:

>1530_bases
ATGATGCCTCCCACGCGTGTCGTTCTTCGCCTTGCCGTTTGCGCAGCCGTCACGGCCGCGCTCCTGCCGTGTGCGTCATC
CGTCCGTGCGCAACAGCCGGCGTCCGCCCCGCCCGCTTCTGCACCCGCCGCTCAACCGCCATCGCCCTGCCCGCCCGACT
GGGAACCGCAGATCTGCGAGCTCAAGGCGGCTGTCGAAGTGCTCAAGAAACAGCACCTGACCGACATCGACATCGGCGCG
CTGCTCGACGCAACGACCCACGCGGGAATCAAGACACTGCCGTACGCGCGTTTCTTCGACGCGAAGGAGGAGCAGGAGCG
GCGCGACGACGAACGGCGCGCGCGCGACGGCACGCCCGGCATCGGCATCGTGTTCGAGACGCGGCCCGACGGGCTGCACA
TCGTCGACGTGATTCCCGACGCGCCCGCGGAAAAAGCCGGCGTGCGTCCCGACGATCTGGTCGTCGCGATGAACGATACG
AGCGTCGTCGGCATCGACCCCGCCGACCTGGCCAAACTCTCCAAGGGCGACGCGGGCGTACCGCTGAAACTCACGGTCCA
GCGCGGCCCGTCGCACACGGTGCTGAACTTCGCGCCCGTGCGGACGATCCTCAAGCCGCATCCCGCGACCGCGAAACGGC
TCGACGGCGACATCCTGTACACGCGGCTGTCGAGCTTCCCCGAACCGGCGGTCGGCGACTACATCGACGCGGTGCAGGCC
GCGCGCCGCGCGGGCCCGCCGGTGAAAGGCCTGATTCTCGACCTGCGCATCAACGGCGGCGGCGCGCTCAATGCGGCGAT
CGGCATCACCGCGCTGTTCACGGGTCGCGACCGCACCGCGATGGTGACGGTCGAGCGCGGCGATGCCAACCGCCGCCGCT
ACACGACCAACTGGCCCGATTACGAATTGCCGGTCATGCACGGCCAGGACCCGCTCGCGACGCTGCAGACGGACGTCTGG
TGGCGTACCGTGCCGCTCGTCGTGCTCGTCGACGGACAGAGCGCGTCGGCCGCCGAGGCGACCGCGGCAGCGCTGAAGGA
TCTCGGCCGCGCGAAGCTGCTCGGCATGCCGACTTACGGGAAGGGGCTCGCGCAGACGGGCGTCGACCTGATCGACGGCA
CCCGCCTGAATTTCACGTACGCGCGCAACCTGCGGCCGAACGGCTGCCCGATGGACGGCTACGGCGTCGTGCCGGACTGG
CTCGTGCCACCGCGCCGCGACTCGGACGTCGACGGCGTGCTGCTGTGGTACCGGGAAGCCGATCTCCCCCGTGCGCCGTA
TGCGGACCGGCTGGCGCCCGATCCGTTCGCGAAGGTGCGCAAGGAACGGCAGAAGCTGCGCGAGCAACGTGCGCTCGCGA
AGATCGATACGGCGAAGAGCGCGGCGCTGCCGCAGCGCGAGTTCGGCACGGCAACCGACTGGCAACTCAGGCAGGCGCTT
GCCGCGCTCGCCGGGCGCCCGGTGCGGACCATCGAAGCCAAACCGCAACTGATGCCGGCACGGCCCGTATGCGAGCGCGC
CGGCAACTGA

Upstream 100 bases:

>100_bases
CGCGCGCGTCGGCTACAATCGTGACCGTCCCGCCGCGCCGCCCGCCGGCTGTGCGTCGGCAGGACAGCACCTTCGCCCTC
CGTTCAAACGTGCGGTCCCG

Downstream 100 bases:

>100_bases
CGCGCCCCGCGCCGCACCGCCCGGTTACCGGAACCCGAACCGCTTGCGCAGCACGACCAGCGCCACGAGGCTCAGTACGG
CCGCGAACATCAGGTAGAAG

Product: peptidase S41

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MMPPTRVVLRLAVCAAVTAALLPCASSVRAQQPASAPPASAPAAQPPSPCPPDWEPQICELKAAVEVLKKQHLTDIDIGA
LLDATTHAGIKTLPYARFFDAKEEQERRDDERRARDGTPGIGIVFETRPDGLHIVDVIPDAPAEKAGVRPDDLVVAMNDT
SVVGIDPADLAKLSKGDAGVPLKLTVQRGPSHTVLNFAPVRTILKPHPATAKRLDGDILYTRLSSFPEPAVGDYIDAVQA
ARRAGPPVKGLILDLRINGGGALNAAIGITALFTGRDRTAMVTVERGDANRRRYTTNWPDYELPVMHGQDPLATLQTDVW
WRTVPLVVLVDGQSASAAEATAAALKDLGRAKLLGMPTYGKGLAQTGVDLIDGTRLNFTYARNLRPNGCPMDGYGVVPDW
LVPPRRDSDVDGVLLWYREADLPRAPYADRLAPDPFAKVRKERQKLREQRALAKIDTAKSAALPQREFGTATDWQLRQAL
AALAGRPVRTIEAKPQLMPARPVCERAGN

Sequences:

>Translated_509_residues
MMPPTRVVLRLAVCAAVTAALLPCASSVRAQQPASAPPASAPAAQPPSPCPPDWEPQICELKAAVEVLKKQHLTDIDIGA
LLDATTHAGIKTLPYARFFDAKEEQERRDDERRARDGTPGIGIVFETRPDGLHIVDVIPDAPAEKAGVRPDDLVVAMNDT
SVVGIDPADLAKLSKGDAGVPLKLTVQRGPSHTVLNFAPVRTILKPHPATAKRLDGDILYTRLSSFPEPAVGDYIDAVQA
ARRAGPPVKGLILDLRINGGGALNAAIGITALFTGRDRTAMVTVERGDANRRRYTTNWPDYELPVMHGQDPLATLQTDVW
WRTVPLVVLVDGQSASAAEATAAALKDLGRAKLLGMPTYGKGLAQTGVDLIDGTRLNFTYARNLRPNGCPMDGYGVVPDW
LVPPRRDSDVDGVLLWYREADLPRAPYADRLAPDPFAKVRKERQKLREQRALAKIDTAKSAALPQREFGTATDWQLRQAL
AALAGRPVRTIEAKPQLMPARPVCERAGN
>Mature_509_residues
MMPPTRVVLRLAVCAAVTAALLPCASSVRAQQPASAPPASAPAAQPPSPCPPDWEPQICELKAAVEVLKKQHLTDIDIGA
LLDATTHAGIKTLPYARFFDAKEEQERRDDERRARDGTPGIGIVFETRPDGLHIVDVIPDAPAEKAGVRPDDLVVAMNDT
SVVGIDPADLAKLSKGDAGVPLKLTVQRGPSHTVLNFAPVRTILKPHPATAKRLDGDILYTRLSSFPEPAVGDYIDAVQA
ARRAGPPVKGLILDLRINGGGALNAAIGITALFTGRDRTAMVTVERGDANRRRYTTNWPDYELPVMHGQDPLATLQTDVW
WRTVPLVVLVDGQSASAAEATAAALKDLGRAKLLGMPTYGKGLAQTGVDLIDGTRLNFTYARNLRPNGCPMDGYGVVPDW
LVPPRRDSDVDGVLLWYREADLPRAPYADRLAPDPFAKVRKERQKLREQRALAKIDTAKSAALPQREFGTATDWQLRQAL
AALAGRPVRTIEAKPQLMPARPVCERAGN

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=306, Percent_Identity=28.7581699346405, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 54957; Mature: 54957

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPPTRVVLRLAVCAAVTAALLPCASSVRAQQPASAPPASAPAAQPPSPCPPDWEPQICE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LKAAVEVLKKQHLTDIDIGALLDATTHAGIKTLPYARFFDAKEEQERRDDERRARDGTPG
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHCCCHHHHCCHHHHHHHHHHHHHCCCCCC
IGIVFETRPDGLHIVDVIPDAPAEKAGVRPDDLVVAMNDTSVVGIDPADLAKLSKGDAGV
EEEEEEECCCCEEEEEECCCCCHHHCCCCCCCEEEEECCCEEEECCHHHHHHHCCCCCCC
PLKLTVQRGPSHTVLNFAPVRTILKPHPATAKRLDGDILYTRLSSFPEPAVGDYIDAVQA
CEEEEEECCCCCEEEEHHHHHHHHCCCCCHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
ARRAGPPVKGLILDLRINGGGALNAAIGITALFTGRDRTAMVTVERGDANRRRYTTNWPD
HHHCCCCCEEEEEEEEECCCCCEEHHEEEEEEEECCCCEEEEEEECCCCCCCEEECCCCC
YELPVMHGQDPLATLQTDVWWRTVPLVVLVDGQSASAAEATAAALKDLGRAKLLGMPTYG
CCCCEECCCCCHHHHHHCCEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCC
KGLAQTGVDLIDGTRLNFTYARNLRPNGCPMDGYGVVPDWLVPPRRDSDVDGVLLWYREA
CCHHHCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC
DLPRAPYADRLAPDPFAKVRKERQKLREQRALAKIDTAKSAALPQREFGTATDWQLRQAL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHH
AALAGRPVRTIEAKPQLMPARPVCERAGN
HHHCCCCEEEECCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MMPPTRVVLRLAVCAAVTAALLPCASSVRAQQPASAPPASAPAAQPPSPCPPDWEPQICE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LKAAVEVLKKQHLTDIDIGALLDATTHAGIKTLPYARFFDAKEEQERRDDERRARDGTPG
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHCCCHHHHCCHHHHHHHHHHHHHCCCCCC
IGIVFETRPDGLHIVDVIPDAPAEKAGVRPDDLVVAMNDTSVVGIDPADLAKLSKGDAGV
EEEEEEECCCCEEEEEECCCCCHHHCCCCCCCEEEEECCCEEEECCHHHHHHHCCCCCCC
PLKLTVQRGPSHTVLNFAPVRTILKPHPATAKRLDGDILYTRLSSFPEPAVGDYIDAVQA
CEEEEEECCCCCEEEEHHHHHHHHCCCCCHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
ARRAGPPVKGLILDLRINGGGALNAAIGITALFTGRDRTAMVTVERGDANRRRYTTNWPD
HHHCCCCCEEEEEEEEECCCCCEEHHEEEEEEEECCCCEEEEEEECCCCCCCEEECCCCC
YELPVMHGQDPLATLQTDVWWRTVPLVVLVDGQSASAAEATAAALKDLGRAKLLGMPTYG
CCCCEECCCCCHHHHHHCCEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCC
KGLAQTGVDLIDGTRLNFTYARNLRPNGCPMDGYGVVPDWLVPPRRDSDVDGVLLWYREA
CCHHHCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC
DLPRAPYADRLAPDPFAKVRKERQKLREQRALAKIDTAKSAALPQREFGTATDWQLRQAL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHH
AALAGRPVRTIEAKPQLMPARPVCERAGN
HHHCCCCEEEECCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA