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The map label for this gene is rnb [H]

Identifier: 78065170

GI number: 78065170

Start: 581266

End: 583353

Strand: Direct

Name: rnb [H]

Synonym: Bcep18194_A3694

Alternate gene names: 78065170

Gene position: 581266-583353 (Clockwise)

Preceding gene: 78065169

Following gene: 78065171

Centisome position: 15.73

GC content: 68.34

Gene sequence:

>2088_bases
GTGAACGTTTTCTTCGAGGAATCGGGCAGTTTCAAGGCGGGCAGCGTGCTGTCGCGCCAGGGCGACGCGTTTCAGGTCGA
GTTGCCCGGCGGGCGGCGGGCGAAGGTGCGCGCGAAAGACGTGCTGATCGAATTCGACAAGCCGGCCGCAAGCGAGCTGA
TGCAGGAGGCCGACTCGGCCGCGCAGCAGATCGATCTGGACTTCCTGTGGGAATGCGCGCCGGCCGACGAGTTCGCGTAC
ACGGCGCTGGCCGCGGAATACTTCGGCGCGACGTACGGCCCGGTCGAGCGCGCGGCGCTGGTGTTGCGACTGCACGGCTC
GCCCGTCTACTTCCGCCGCAAGGGGCGCGGCCAGTACCAGCGCGCGCCGGAAGAGCAGCTCAAGATGGCGCTCGCGTCGC
TCGAGCGCAAGCGCCAGCAGGCGCTCGTCCAGGTGCAGTATGAAGAGGAACTGAAGGCCGGCAAGCTGCCGGAAGCGTTC
GCGGGCAAGGTGCTCGGGCTGCTGACGCGGCCGGACAAGAACGCGATCGAATACAAGGCGATGGAAGCGGCGGCCGGTGC
GCGCGGCGTGTCGCCTGCGCGGCTGATGCTCGACTGCGGCGGCATCGCGTCGCCGCGTGCGCTGCACGAGGCGCGCTTCC
TCGCCGAATTCTTCCCGCACGGCACGGGCTTTCCGGCCGTCACGGTCGGCGCGCTGCCGGACGACCTGCCGCGTGCGGAC
GTCCAGGCGTTCTCGATCGACGACATCACGACGACCGAAATCGACGACGCGTTCTCGGTCGAGCACCTGGCCGACGGCCG
CGTGCGGATCGGCGTGCACATCGCGGCACCGGCGCTCGGCATCGTGCGCGGCGACTCGGTCGACGCGATCGCGCGTACGC
GCCTGTCGACCGTGTACATGCCGGGCGACAAGATCACGATGCTGCCGGACGACGTTGTCGACGTGTTCACGCTGAAAGAG
GGCGACTACCGCCCGGCACTGTCGCTGTACATCATCGTCAACCGCGAAACCCAGGAGATCGTCGCGAACGAGACGCGCGC
CGAGCTCGTGTTCGTGAAGAACAACCTGCGCCACAACCACCTCGACGAGCTCGTCAACGAAGAGACGCTCGCAGCCGGCA
CCGGCGACTATCCGCACAAGGACGACATCGCCGTGCTGTGGCCGCTCGCGCAGGCGCTGTTCGAGAAGCGCCAGGTCGCG
CGCGCGGGCTACGGCCTGAAGCGCGAGGTGCAGCGCAACACCGACTACAACTTCTATGTCGAAGGCGAGCACGTGTCGAT
CACGCCGCGCCGTCGCGGGTCGCCGCTCGACCTGATCGTGTCGGAGCTCGCGATCCTCGCGAACTCGACCTGGGGCGCGT
TCCTGCACGACCACACGGTGCCGGGCATCTACCGCTCGCAGCGCGGCTTCGGCGCGCCGGGCCCGAAGCGCACGCGGATG
CAGACGACGGCCGCGCCGCACGAAGGCCTCGGCGTCGCGCAGTATGCGTGGAGCACGTCGCCGCTGCGCCGTTACGTTGA
CCTCGTGAACCAGTGGCAATTGCTCGCCTGCGTGCAGCATGGCGTCACCGCGAAGCTCGCCGCGCCGTTCAAGCCGAAGG
ACGCCGACCTGTACGCGGTCGTGCAGGGCTTCGACGACACCTACACGGCCTACGCCGACTATCAGCGCCGGATGGAATAT
TTCTGGTGCCTGCGCTGGCTCGCGCAGGAGCAGAAGAAGCAGGTCGTCGCGAGCGTCGTGAAGGGCGATCTGGTGCGCCT
CGAGGAAATTCCGCTGCTGCTGCACGTGCCGGGGCTCGGCGTGCATGCGCGCGGCACGCGCGTGCTGCTCGACGTGATGT
CGCTCGACGAGCTGACGATCGAGGCATCGGTGCGGTTGCTGAACGTGCTCGACGCGCCGACCGTGACGAGCGGCGATGCT
GCCGAGGAAGAAGATGACGCCGAAGGCGGCGACGACACGCTGATCGACGCCGAAGACGCGACGGCCGAAACCGAAGCCGA
AGCGCTGGCGGAAGCGGACGGCGCGACGGCCGGTGAAGGCGGCGAAGCCGCGAACGGTAACGCCAGCGAAGAGGGGCGCG
CATCATGA

Upstream 100 bases:

>100_bases
GCGACGGAAAGACGTCTTAAACCGGCCATGTGCCGATCGAATTCCCATCATCATGCGGCGCCGCCGACGTGGCGCCCGGC
AGTCTGAACGAGAGTACTGA

Downstream 100 bases:

>100_bases
CCGCGGCTGCGTCGACGAGCGGCGCCGACCGCTATGTAGTGTTCGGCAACCCGGTGGCGCACAGCAAGTCGCCATTCATC
CACGCGCAGTTCGCCGCGCA

Product: ribonuclease II

Products: NA

Alternate protein names: Exoribonuclease II; RNase II; Ribonuclease II [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAASELMQEADSAAQQIDLDFLWECAPADEFAY
TALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQRAPEEQLKMALASLERKRQQALVQVQYEEELKAGKLPEAF
AGKVLGLLTRPDKNAIEYKAMEAAAGARGVSPARLMLDCGGIASPRALHEARFLAEFFPHGTGFPAVTVGALPDDLPRAD
VQAFSIDDITTTEIDDAFSVEHLADGRVRIGVHIAAPALGIVRGDSVDAIARTRLSTVYMPGDKITMLPDDVVDVFTLKE
GDYRPALSLYIIVNRETQEIVANETRAELVFVKNNLRHNHLDELVNEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVA
RAGYGLKREVQRNTDYNFYVEGEHVSITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDADLYAVVQGFDDTYTAYADYQRRMEY
FWCLRWLAQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLGVHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDA
AEEEDDAEGGDDTLIDAEDATAETEAEALAEADGATAGEGGEAANGNASEEGRAS

Sequences:

>Translated_695_residues
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAASELMQEADSAAQQIDLDFLWECAPADEFAY
TALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQRAPEEQLKMALASLERKRQQALVQVQYEEELKAGKLPEAF
AGKVLGLLTRPDKNAIEYKAMEAAAGARGVSPARLMLDCGGIASPRALHEARFLAEFFPHGTGFPAVTVGALPDDLPRAD
VQAFSIDDITTTEIDDAFSVEHLADGRVRIGVHIAAPALGIVRGDSVDAIARTRLSTVYMPGDKITMLPDDVVDVFTLKE
GDYRPALSLYIIVNRETQEIVANETRAELVFVKNNLRHNHLDELVNEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVA
RAGYGLKREVQRNTDYNFYVEGEHVSITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDADLYAVVQGFDDTYTAYADYQRRMEY
FWCLRWLAQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLGVHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDA
AEEEDDAEGGDDTLIDAEDATAETEAEALAEADGATAGEGGEAANGNASEEGRAS
>Mature_695_residues
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAASELMQEADSAAQQIDLDFLWECAPADEFAY
TALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQRAPEEQLKMALASLERKRQQALVQVQYEEELKAGKLPEAF
AGKVLGLLTRPDKNAIEYKAMEAAAGARGVSPARLMLDCGGIASPRALHEARFLAEFFPHGTGFPAVTVGALPDDLPRAD
VQAFSIDDITTTEIDDAFSVEHLADGRVRIGVHIAAPALGIVRGDSVDAIARTRLSTVYMPGDKITMLPDDVVDVFTLKE
GDYRPALSLYIIVNRETQEIVANETRAELVFVKNNLRHNHLDELVNEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVA
RAGYGLKREVQRNTDYNFYVEGEHVSITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDADLYAVVQGFDDTYTAYADYQRRMEY
FWCLRWLAQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLGVHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDA
AEEEDDAEGGDDTLIDAEDATAETEAEALAEADGATAGEGGEAANGNASEEGRAS

Specific function: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1787542, Length=360, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011804 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: =3.1.13.1 [H]

Molecular weight: Translated: 76066; Mature: 76066

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAASELMQEADSA
CCEEECCCCCCCCCCHHCCCCCEEEEECCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHH
AQQIDLDFLWECAPADEFAYTALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQ
HHHCCHHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHEEEEEEECCCEEEEEECCCCCCC
RAPEEQLKMALASLERKRQQALVQVQYEEELKAGKLPEAFAGKVLGLLTRPDKNAIEYKA
CCCHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCHHHHHHHHHEEECCCCCCHHHHH
MEAAAGARGVSPARLMLDCGGIASPRALHEARFLAEFFPHGTGFPAVTVGALPDDLPRAD
HHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC
VQAFSIDDITTTEIDDAFSVEHLADGRVRIGVHIAAPALGIVRGDSVDAIARTRLSTVYM
CEEEEECCCEECCCCCHHCHHHHCCCEEEEEEEEECCEEEEEECCCHHHHHHHHHEEEEE
PGDKITMLPDDVVDVFTLKEGDYRPALSLYIIVNRETQEIVANETRAELVFVKNNLRHNH
CCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEECCHHHHHHCCCCEEEEEEECCCCHHH
LDELVNEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVARAGYGLKREVQRNTDYNFYV
HHHHHCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEE
EGEHVSITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
ECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCCE
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDADLYAV
EECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
VQGFDDTYTAYADYQRRMEYFWCLRWLAQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCEEEEECCCC
VHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDAAEEEDDAEGGDDTLIDAEDA
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
TAETEAEALAEADGATAGEGGEAANGNASEEGRAS
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAASELMQEADSA
CCEEECCCCCCCCCCHHCCCCCEEEEECCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHH
AQQIDLDFLWECAPADEFAYTALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQ
HHHCCHHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHEEEEEEECCCEEEEEECCCCCCC
RAPEEQLKMALASLERKRQQALVQVQYEEELKAGKLPEAFAGKVLGLLTRPDKNAIEYKA
CCCHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCHHHHHHHHHEEECCCCCCHHHHH
MEAAAGARGVSPARLMLDCGGIASPRALHEARFLAEFFPHGTGFPAVTVGALPDDLPRAD
HHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC
VQAFSIDDITTTEIDDAFSVEHLADGRVRIGVHIAAPALGIVRGDSVDAIARTRLSTVYM
CEEEEECCCEECCCCCHHCHHHHCCCEEEEEEEEECCEEEEEECCCHHHHHHHHHEEEEE
PGDKITMLPDDVVDVFTLKEGDYRPALSLYIIVNRETQEIVANETRAELVFVKNNLRHNH
CCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEECCHHHHHHCCCCEEEEEEECCCCHHH
LDELVNEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVARAGYGLKREVQRNTDYNFYV
HHHHHCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEE
EGEHVSITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
ECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCCE
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDADLYAV
EECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
VQGFDDTYTAYADYQRRMEYFWCLRWLAQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCEEEEECCCC
VHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDAAEEEDDAEGGDDTLIDAEDA
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
TAETEAEALAEADGATAGEGGEAANGNASEEGRAS
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA