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The map label for this gene is aroE

Identifier: 78065171

GI number: 78065171

Start: 583350

End: 584216

Strand: Direct

Name: aroE

Synonym: Bcep18194_A3695

Alternate gene names: 78065171

Gene position: 583350-584216 (Clockwise)

Preceding gene: 78065170

Following gene: 78065172

Centisome position: 15.79

GC content: 72.43

Gene sequence:

>867_bases
ATGACCGCGGCTGCGTCGACGAGCGGCGCCGACCGCTATGTAGTGTTCGGCAACCCGGTGGCGCACAGCAAGTCGCCATT
CATCCACGCGCAGTTCGCCGCGCAGACGGGCGAGCCGGTCGAGTACACGCACCGGCTTGCGCCGGTCGACGGTTTCGACG
CGGCCGTGCGCGCGTTCGTCGCCGAAGGTGGTCGCGGTGCGAACGTGACGGTGCCGTTCAAGCTCGAAGCGCATGCGCTC
GCCGACACGCTGTCGCCGCGCGCGGCAGCGGCGGGCGCCGTGAATACGCTGCGCATCGATGTCGATGGCCGCATCCACGG
CGACAACACCGACGGTGTCGGCCTCGTGCGCGACATCGAAGCGAATCTCGGCGTGTCGCTGGCGGGCGCCCGCATCCTGC
TGCTCGGCGCGGGTGGCGCGGCGCGCGGGGTCGTGCTGCCGCTGCTCGACCGCGCGCCGCTGTCGATCACGATCGTGAAC
CGTACCGCGAGCAAGGCCGAGGCACTCGTCGGCCAGTTCATGCAGGCCGCGCACGACGCGGGCTGCACGCTCGCGGGCGG
CGGCCCCGATGTCGTGCGCGCGGAGCGGTACGACGTGGTGATCAACGCGACGGCCGGCAGCCTCGATGCCGCGCTGCCGG
AGTGTGATGCGGCGGCATTCGGCGCAGGCACGCTCGCGTACGACATGATGTACGGCGCGCAGCCGACGGTGTTCATGCAG
CACGCGGCGTCGCTCGGCGCGCGCACGGCCGACGGGCTCGGGATGCTCGTCGAGCAGGCGGCCGAATCGTTCTTCATCTG
GCGCGGCGTGCGGCCGGACGGCGCACCGGTGCTGGCCGCGCTGCGCCAGGCGCTCGCGGCGAGCTGA

Upstream 100 bases:

>100_bases
CCGAAACCGAAGCCGAAGCGCTGGCGGAAGCGGACGGCGCGACGGCCGGTGAAGGCGGCGAAGCCGCGAACGGTAACGCC
AGCGAAGAGGGGCGCGCATC

Downstream 100 bases:

>100_bases
ACGGAGCGCGGCTCGTGGTGGCGGTGAGCGGCACGCAGCACACGCGGACGGTGAGCCCGACCCGCTGGATCGTCTATGCG
GGATCGGTGTTCGCGGGCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTAAASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPVEYTHRLAPVDGFDAAVRAFVAEGGRGANVTVPFKLEAHAL
ADTLSPRAAAAGAVNTLRIDVDGRIHGDNTDGVGLVRDIEANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSITIVN
RTASKAEALVGQFMQAAHDAGCTLAGGGPDVVRAERYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS

Sequences:

>Translated_288_residues
MTAAASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPVEYTHRLAPVDGFDAAVRAFVAEGGRGANVTVPFKLEAHAL
ADTLSPRAAAAGAVNTLRIDVDGRIHGDNTDGVGLVRDIEANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSITIVN
RTASKAEALVGQFMQAAHDAGCTLAGGGPDVVRAERYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS
>Mature_287_residues
TAAASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPVEYTHRLAPVDGFDAAVRAFVAEGGRGANVTVPFKLEAHALA
DTLSPRAAAAGAVNTLRIDVDGRIHGDNTDGVGLVRDIEANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSITIVNR
TASKAEALVGQFMQAAHDAGCTLAGGGPDVVRAERYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQH
AASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=47.841726618705, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1787983, Length=261, Percent_Identity=28.3524904214559, Blast_Score=99, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=165, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29357; Mature: 29225

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPVEYTHRLAPVDGFDAAVRAFV
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHEECCCCCHHHHHHHHH
AEGGRGANVTVPFKLEAHALADTLSPRAAAAGAVNTLRIDVDGRIHGDNTDGVGLVRDIE
HCCCCCCEEEEEEEEEHHHHHHHCCCHHHHCCCCEEEEEEECCEEECCCCCCCEEEEEEC
ANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSITIVNRTASKAEALVGQFMQAAHDA
CCCCEEECCCEEEEEECCCCCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC
GCTLAGGGPDVVRAERYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CCEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHH
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS
HHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TAAASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPVEYTHRLAPVDGFDAAVRAFV
CCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHEECCCCCHHHHHHHHH
AEGGRGANVTVPFKLEAHALADTLSPRAAAAGAVNTLRIDVDGRIHGDNTDGVGLVRDIE
HCCCCCCEEEEEEEEEHHHHHHHCCCHHHHCCCCEEEEEEECCEEECCCCCCCEEEEEEC
ANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSITIVNRTASKAEALVGQFMQAAHDA
CCCCEEECCCEEEEEECCCCCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC
GCTLAGGGPDVVRAERYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CCEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHH
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS
HHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA