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The map label for this gene is obgE

Identifier: 78065144

GI number: 78065144

Start: 554071

End: 555183

Strand: Direct

Name: obgE

Synonym: Bcep18194_A3668

Alternate gene names: 78065144

Gene position: 554071-555183 (Clockwise)

Preceding gene: 78065143

Following gene: 78065145

Centisome position: 15.0

GC content: 66.58

Gene sequence:

>1113_bases
ATGAAGTTCATTGACGAAGCACGAATCGAAGTCATCGCCGGAGACGGAGGCGATGGCAGTGCGTCGATGCGCCGCGAGAA
ATTCGTCCCGTTCGGCGGGCCGGACGGCGGCGACGGCGGCCGGGGCGGTAGCGTATACGCGATCGCCGACCGCAACATCA
ACACGCTGATCGACTACCGTTACGCGAAGAAGCATCTGGCGCGCAACGGCGAAAACGGGCGCGGCTCGGATTGTTACGGC
AAGGGCGGCGACGACGTCACGCTGCGCATGCCGGTCGGCACGATCATCAGCGACATGGATACCGGCGAGCTGATCGCCGA
CCTGACCGAGCACGACCAGCAGGTGATGCTTGCGCAGGGCGGCTCCGGCGGGCTCGGCAACCTGCATTTCAAGTCGAGCA
CGAACCGCGCACCGCGGCAGAAGACGGACGGCAAGCCCGGCGAGCGTCGCATGCTGAGGCTCGAACTGAAGGTGCTCGCC
GACGTCGGCCTGCTCGGCATGCCGAACGCGGGCAAGTCGACGTTCATTTCGTCTGTGTCGAACGCGAGGCCGAAGATTGC
CGACTACCCGTTCACGACGCTTGCGCCGAATCTCGGCGTGGTGCGTGTCGGTCCGAGCAAGAGCTTCGTGATCGCGGACA
TCCCGGGGCTGATCGAGGGCGCCGCCGAAGGCGCGGGCCTCGGCCACCAGTTCCTGCGCCACCTGCAGCGCACCGGCGTG
CTGCTGCATCTGGTCGATCTCGCACCGTTCGACGAAAGCGTCGATCCGGTTGCGGAAGCGACGGCGATCGTCGGCGAGCT
GCGCAAGTACGACGAGGCGCTCTACGAAAAGCCGCGCTGGCTCGTGCTCAACAAGCTCGACATGGTGCCGGAAGACGAGC
GCAAGGCGCGCGTCGCGGATTTCCTCGAGCGCTTCGAGTGGGACGGCCCCGTGTTCGAGATCTCGGCACTGACGGGCCAG
GGCTGTGAAGCGCTGTGCTACGCGATCTACGACTACCTCGCCGAACATTCGGACGCGCATCGTGCGGCGGAGGCGGAAGA
TCTCGCGGCGGACGTGCGTTTCCGCGACGAGCCGCCTGCCAAGGGCGGTGCGGCGCCGGGCGACGACGCCTGA

Upstream 100 bases:

>100_bases
CGGCGACCATCGCGCAACCGGCGTACGATCGGCCGAATGGCAGATTGTTCAAGCGCGCCGGCGCGCGGCACAATAGCGGA
AATACTGGGCGGAGTGACGA

Downstream 100 bases:

>100_bases
GCGATTCCGGAACGCGCCGGGCGTGCCGCCCGGCGTCAGCGTTCAATCGCGCCCCGGCCGGGCAGGCAGCAGATACAGGA
GACAGTGCAGGATGCGTTCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDVTLRMPVGTIISDMDTGELIADLTEHDQQVMLAQGGSGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNARPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDESVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERKARVADFLERFEWDGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDEPPAKGGAAPGDDA

Sequences:

>Translated_370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDVTLRMPVGTIISDMDTGELIADLTEHDQQVMLAQGGSGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNARPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDESVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERKARVADFLERFEWDGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDEPPAKGGAAPGDDA
>Mature_370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDVTLRMPVGTIISDMDTGELIADLTEHDQQVMLAQGGSGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNARPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDESVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERKARVADFLERFEWDGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDEPPAKGGAAPGDDA

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=38.6904761904762, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI111955139, Length=388, Percent_Identity=35.0515463917526, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI111955063, Length=294, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=32.3529411764706, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1789574, Length=336, Percent_Identity=57.4404761904762, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790615, Length=212, Percent_Identity=29.7169811320755, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=339, Percent_Identity=36.8731563421829, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=29.9382716049383, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=197, Percent_Identity=37.5634517766497, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6321773, Length=158, Percent_Identity=28.4810126582279, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585318, Length=296, Percent_Identity=39.527027027027, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI20129375, Length=336, Percent_Identity=36.3095238095238, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39797; Mature: 39797

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDVTLRMPVGTIISDMDTGELIADLTEHDQQVMLAQG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHCCCHHHHHHHHHHCCCEEEEEEC
GSGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NARPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDLAPFDESVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERKARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FLERFEWDGPVFEISALTGQGCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDEPPA
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEECCCCCC
KGGAAPGDDA
CCCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDVTLRMPVGTIISDMDTGELIADLTEHDQQVMLAQG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHCCCHHHHHHHHHHCCCEEEEEEC
GSGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NARPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDLAPFDESVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERKARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FLERFEWDGPVFEISALTGQGCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDEPPA
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEECCCCCC
KGGAAPGDDA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA