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The map label for this gene is ftsW [H]

Identifier: 78065120

GI number: 78065120

Start: 528846

End: 530129

Strand: Direct

Name: ftsW [H]

Synonym: Bcep18194_A3644

Alternate gene names: 78065120

Gene position: 528846-530129 (Clockwise)

Preceding gene: 78065119

Following gene: 78065121

Centisome position: 14.32

GC content: 66.04

Gene sequence:

>1284_bases
ATGAGCTGGTCCGATCGCCTCGTCTCCCGTTTCAACGATCGCCGCGACACCGGCGGCAATGCCGCGGGCGGCCGCGTCGC
GTCCGCCACGCGCGCCGCGACGGGCGGCCTTGCGAGCGTCGTCAACGGCGTGCGCCCGAGCCGTTCGCGGATGCTCGACT
TCGACTACTCGCTGCTGTGGGTCGCAATCGCGCTGCTCGGGCTCGGCGTCGTGATGGTGTACTCGGCGTCGATCGCGATG
CCCGATTCGCCGAAATACGCGTCGTATCACGATTACGCGTTCCTGATGCGCCACTGCATCTCGCTCGTCGTCGCGTTCAT
CGCGGCGGTGATCGCGTTCCGCGTGCCGGTGTCGACGTGGGACAAATACGCGCCGCAACTCTTCCTGATCGCGCTCGTCA
GCCTCGTGATCGTGCTGATTCCGCACGTCGGCAAGGGCGTGAACGGTGCGCGCCGCTGGATTCCGCTCGGCATCACGAAC
ATGCAGCCGTCGGAAATCATGAAGCTCGCGGTGACGATCTACGCGGCGAACTACACGGTGCGCAAGCAGGAATACATGCA
GAGCTTCGCCAAGGGCTTCCTGCCGATGGCGTTCGCAGTCGGCCTGGTCGGTGCGCTGCTGCTGCTCGAGCCGGACATGG
GCGCGTTCATGGTGGTCGCGGCGATCGCGATGGGCGTGCTGTTCCTCGGCGGCGTGAACGGCAAGCTGTTCGGTGGCCTC
GTTGCGACCGCGATCGGCACCTTCACGATGCTGGTGTGGCTGTCGCCGTGGCGTCGCGAGCGGATCTTCGCGTACCTCGA
TCCGTGGGACGAGCGCTACGCGCAGGGCAAGGCGTACCAGCTCACGCACTCGCTGATCGCGTTCGGCCGCGGCGAATGGT
TCGGTGTCGGCCTCGGCGGCAGCGTCGAGAAGCTGAACTACCTGCCGGAAGCGCATACCGACTTCATCCTCGCGGTGATC
GGCGAGGAGCTCGGTTTCGTCGGCGTGCTGGTCGTGATCCTGCTCTTCTACTGGATCGTGCGCCGCGCGTTCGAGATCGG
CCGCCAGGCGCTCGCACTCGATCGCACGTTCGCGGGCCTGATGGCGAAGGGTATCGGCATCTGGTTCGGTGCGCAGACCT
TCATCAACATGGGCGTGAACCTCGGGCTGCTGCCGACCAAGGGCCTGACGCTGCCGCTCGTGAGCTACGGCGGCTCGGGC
ATTCTGCTGAACTGCGTCGCGCTCGCGGTGCTGCTGCGGGTCGACTATGAAAACCGGGTGCTGATGCGCGGAGGGAAGGT
ATGA

Upstream 100 bases:

>100_bases
CTGCATGCGCGAGCCTCGACATGTTCAGGAACTACGCCCATCGCGCGGATGTGTTCCGCGCGGCGGTCGACGAAATCGCC
ATCGACAAAGGAGCGACGCC

Downstream 100 bases:

>100_bases
CCGCGTCGCAACGCACGCTGATGGTGATGGCAGGCGGCACCGGGGGCCACGTGTTCCCGGGGCTCGCGGTCGCGCACCGG
ATGGAAGCGGCGGGCTGGCG

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLWVAIALLGLGVVMVYSASIAM
PDSPKYASYHDYAFLMRHCISLVVAFIAAVIAFRVPVSTWDKYAPQLFLIALVSLVIVLIPHVGKGVNGARRWIPLGITN
MQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGL
VATAIGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVI
GEELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSG
ILLNCVALAVLLRVDYENRVLMRGGKV

Sequences:

>Translated_427_residues
MSWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLWVAIALLGLGVVMVYSASIAM
PDSPKYASYHDYAFLMRHCISLVVAFIAAVIAFRVPVSTWDKYAPQLFLIALVSLVIVLIPHVGKGVNGARRWIPLGITN
MQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGL
VATAIGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVI
GEELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSG
ILLNCVALAVLLRVDYENRVLMRGGKV
>Mature_426_residues
SWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLWVAIALLGLGVVMVYSASIAMP
DSPKYASYHDYAFLMRHCISLVVAFIAAVIAFRVPVSTWDKYAPQLFLIALVSLVIVLIPHVGKGVNGARRWIPLGITNM
QPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGLV
ATAIGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIG
EELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGI
LLNCVALAVLLRVDYENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=378, Percent_Identity=43.3862433862434, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=31.7784256559767, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46449; Mature: 46317

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCCCCC
>Mature Secondary Structure 
SWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLW
CHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCHHHEECCCHHHHH
VAIALLGLGVVMVYSASIAMPDSPKYASYHDYAFLMRHCISLVVAFIAAVIAFRVPVSTW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DKYAPQLFLIALVSLVIVLIPHVGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAANYTV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHEECCCCH
RKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
VATAIGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGG
HHHHHHHHHHHHHHCCHHHCCEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCC
SVEKLNYLPEAHTDFILAVIGEELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTFAGL
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCVALAVLLRVDYENRV
HHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEE
LMRGGKV
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]