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The map label for this gene is mlaC [H]

Identifier: 78064993

GI number: 78064993

Start: 384445

End: 385077

Strand: Direct

Name: mlaC [H]

Synonym: Bcep18194_A3516

Alternate gene names: 78064993

Gene position: 384445-385077 (Clockwise)

Preceding gene: 78064992

Following gene: 78064994

Centisome position: 10.41

GC content: 61.45

Gene sequence:

>633_bases
ATGATGAAAAAACTGTTCCTGATCCCCGTATTCGCGGCGCTGTTCTCGTTCGGCAGCGCAGCCCACGCGCAAGTCGACCA
GTCGAACCCGCAAGCGCTGATCAAGACGGCGACGCAGCAGGTGCTCGACGAAGTCAAACAGCAGACGATCAAGCAGGGCG
ACACCAATCGCATCATTACGATCGTCAACAAGGACATCCTGCCGTACACCGATTTCCGCCGCACCACGCAGCTCGCGATG
GGCCGCAACTGGCGCACCGCGACGGCCGAGCAGCAGCAGCAGGTTCAGGAGCAGTTCAAGCTGCTGCTGATCCGCACGTA
TTCGGGCGCGCTGGCGCAGCTGAAGCCGGATCAGCAGATCCAGTACCCGCCGTTCCGCGCCGATCCGGCCGATACCGATG
TCGTGGTCAAGACGGTCGCGATGAACAACGGCCAGCCGGTCCAGATCGATTACCGCCTGTACAAGTCGGCCAACGGCTGG
AAGGTGTATGACCTGAACGTGCTCGGCGCGTGGCTGATCCAGACGTACCAGCAGCAGTTCAACGAGAAGATCCAGCAAAG
CGGCGTGGACGGCCTGATCCAGTTCCTCACGCAGCGCAACCAGCAACTTGCCGCCGGCAAGCAAGCGTCGTGA

Upstream 100 bases:

>100_bases
CATTCGTTACAGCCGGAAACGATTCAGTCGGTAGCGTGCGCGAACTTGCGCGTAAGCTACCTGCTCCAACCTCCGCATCG
ACTCATTCATGCAGGTCACT

Downstream 100 bases:

>100_bases
GCGGCTTCGAAGCCGGCTCCTCGCTGACCGTCGCGAGCGCGAAGTCCGCGCTCGCGGACGGTCTTGCGCGCATCGGCGCG
GGCGCGACCGCCGTCGATTG

Product: toluene tolerance

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MMKKLFLIPVFAALFSFGSAAHAQVDQSNPQALIKTATQQVLDEVKQQTIKQGDTNRIITIVNKDILPYTDFRRTTQLAM
GRNWRTATAEQQQQVQEQFKLLLIRTYSGALAQLKPDQQIQYPPFRADPADTDVVVKTVAMNNGQPVQIDYRLYKSANGW
KVYDLNVLGAWLIQTYQQQFNEKIQQSGVDGLIQFLTQRNQQLAAGKQAS

Sequences:

>Translated_210_residues
MMKKLFLIPVFAALFSFGSAAHAQVDQSNPQALIKTATQQVLDEVKQQTIKQGDTNRIITIVNKDILPYTDFRRTTQLAM
GRNWRTATAEQQQQVQEQFKLLLIRTYSGALAQLKPDQQIQYPPFRADPADTDVVVKTVAMNNGQPVQIDYRLYKSANGW
KVYDLNVLGAWLIQTYQQQFNEKIQQSGVDGLIQFLTQRNQQLAAGKQAS
>Mature_210_residues
MMKKLFLIPVFAALFSFGSAAHAQVDQSNPQALIKTATQQVLDEVKQQTIKQGDTNRIITIVNKDILPYTDFRRTTQLAM
GRNWRTATAEQQQQVQEQFKLLLIRTYSGALAQLKPDQQIQYPPFRADPADTDVVVKTVAMNNGQPVQIDYRLYKSANGW
KVYDLNVLGAWLIQTYQQQFNEKIQQSGVDGLIQFLTQRNQQLAAGKQAS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=213, Percent_Identity=27.2300469483568, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23821; Mature: 23821

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKLFLIPVFAALFSFGSAAHAQVDQSNPQALIKTATQQVLDEVKQQTIKQGDTNRIIT
CCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IVNKDILPYTDFRRTTQLAMGRNWRTATAEQQQQVQEQFKLLLIRTYSGALAQLKPDQQI
EECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
QYPPFRADPADTDVVVKTVAMNNGQPVQIDYRLYKSANGWKVYDLNVLGAWLIQTYQQQF
CCCCCCCCCCCCHHEEEEEECCCCCEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
NEKIQQSGVDGLIQFLTQRNQQLAAGKQAS
HHHHHHCCHHHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MMKKLFLIPVFAALFSFGSAAHAQVDQSNPQALIKTATQQVLDEVKQQTIKQGDTNRIIT
CCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IVNKDILPYTDFRRTTQLAMGRNWRTATAEQQQQVQEQFKLLLIRTYSGALAQLKPDQQI
EECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
QYPPFRADPADTDVVVKTVAMNNGQPVQIDYRLYKSANGWKVYDLNVLGAWLIQTYQQQF
CCCCCCCCCCCCHHEEEEEECCCCCEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
NEKIQQSGVDGLIQFLTQRNQQLAAGKQAS
HHHHHHCCHHHHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]