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The map label for this gene is mlaA [H]

Identifier: 78064992

GI number: 78064992

Start: 383380

End: 384336

Strand: Direct

Name: mlaA [H]

Synonym: Bcep18194_A3515

Alternate gene names: 78064992

Gene position: 383380-384336 (Clockwise)

Preceding gene: 78064991

Following gene: 78064993

Centisome position: 10.38

GC content: 68.65

Gene sequence:

>957_bases
ATGCAGACGATCCGCATCAGGCAGGCCGCGCTGGCGGTAGCGGCAGTCGCCGCGTTGAGCGGCTGCGCGACCGTGCAGAC
GCCGACCAAGGGTGATCCGCTCGAAGGCTTCAACCGGTCGATGTACAAGTTCAACGATACGGTCGATACATATGCGCTGA
AGCCGGTCGCGAAGGGCTACCAGTACGTGGTGCCGCAGCCGGTGCGCGACAGCGTGACGAACTTCTTCTCGAACATCGGC
GACGTCTACATCGCGGCGAACAACATCGTGCAGCTGCGGATCGCGGACGGTGTCGGCGACATCATGCGCGTCGTGATCAA
CACGGTGTTCGGTGTCGGCGGCCTGTTCGACGTCGCGACGATCGCGAAGCTGCCGAAGCACACGGCCGACTTCGGGATCA
CGATGGGCCGCTACGGCATGCCGTCGGGCCCGTATCTCGTGCTGCCGCTGCTCGGCCCGAGCACGCTGCGCGACACGGCC
GGCCTGGGCGTCGACTACGTCGGCAACCCGCTCACCTACGTGAAGCCGGATGGCCTGAGCTGGGGCCTGTTCGGCGTCAA
CCTCGTCAACACGCGTTCGAACCTGCTCGGTGCAGGCGACGTGCTGGATGCCGCGGCGCTCGACAAGTATTCGTTCGTGC
GTAACGCGTACCTGCAGCGTCGTCAGATGCTGATCAGCAACGCGCGCGGCGAGGCGGCCGCGACGTCGAGCAACGACGCG
CTGCCGAAGTACGACCTGCCGGAGGACGGCGCGGCACCGGCGGCAGCCGGTACGGCGGGCGCGGCAGCGGTGGGCGGCGC
AACGGCGCCGGCGGGTGCATCGGGCGCGGCAGTGGCCGCACCGGCATCGGGCACGGCCGAATCGCCGAACCCGGCGAGCG
AAACGAACGTGCCGGCGATGCAGGTGGCGCCGCCGTCGCCGGGCGGGTTCCGCTTCCCGAGCATCCGGCTGCACTGA

Upstream 100 bases:

>100_bases
GCTGCACCGGCACCGGTGGCGGTGCCGGCGTCGGCGGTGTCCGCTGCGTCCGGTTCGGCGGCCCAATAACCACACGAGAG
AAAACAAGAGGGTAATGACC

Downstream 100 bases:

>100_bases
CGGATTTACATTCGTTACAGCCGGAAACGATTCAGTCGGTAGCGTGCGCGAACTTGCGCGTAAGCTACCTGCTCCAACCT
CCGCATCGACTCATTCATGC

Product: VacJ-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MQTIRIRQAALAVAAVAALSGCATVQTPTKGDPLEGFNRSMYKFNDTVDTYALKPVAKGYQYVVPQPVRDSVTNFFSNIG
DVYIAANNIVQLRIADGVGDIMRVVINTVFGVGGLFDVATIAKLPKHTADFGITMGRYGMPSGPYLVLPLLGPSTLRDTA
GLGVDYVGNPLTYVKPDGLSWGLFGVNLVNTRSNLLGAGDVLDAAALDKYSFVRNAYLQRRQMLISNARGEAAATSSNDA
LPKYDLPEDGAAPAAAGTAGAAAVGGATAPAGASGAAVAAPASGTAESPNPASETNVPAMQVAPPSPGGFRFPSIRLH

Sequences:

>Translated_318_residues
MQTIRIRQAALAVAAVAALSGCATVQTPTKGDPLEGFNRSMYKFNDTVDTYALKPVAKGYQYVVPQPVRDSVTNFFSNIG
DVYIAANNIVQLRIADGVGDIMRVVINTVFGVGGLFDVATIAKLPKHTADFGITMGRYGMPSGPYLVLPLLGPSTLRDTA
GLGVDYVGNPLTYVKPDGLSWGLFGVNLVNTRSNLLGAGDVLDAAALDKYSFVRNAYLQRRQMLISNARGEAAATSSNDA
LPKYDLPEDGAAPAAAGTAGAAAVGGATAPAGASGAAVAAPASGTAESPNPASETNVPAMQVAPPSPGGFRFPSIRLH
>Mature_318_residues
MQTIRIRQAALAVAAVAALSGCATVQTPTKGDPLEGFNRSMYKFNDTVDTYALKPVAKGYQYVVPQPVRDSVTNFFSNIG
DVYIAANNIVQLRIADGVGDIMRVVINTVFGVGGLFDVATIAKLPKHTADFGITMGRYGMPSGPYLVLPLLGPSTLRDTA
GLGVDYVGNPLTYVKPDGLSWGLFGVNLVNTRSNLLGAGDVLDAAALDKYSFVRNAYLQRRQMLISNARGEAAATSSNDA
LPKYDLPEDGAAPAAAGTAGAAAVGGATAPAGASGAAVAAPASGTAESPNPASETNVPAMQVAPPSPGGFRFPSIRLH

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=231, Percent_Identity=36.7965367965368, Blast_Score=130, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 32788; Mature: 32788

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIRIRQAALAVAAVAALSGCATVQTPTKGDPLEGFNRSMYKFNDTVDTYALKPVAKGY
CCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCC
QYVVPQPVRDSVTNFFSNIGDVYIAANNIVQLRIADGVGDIMRVVINTVFGVGGLFDVAT
EEECCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
IAKLPKHTADFGITMGRYGMPSGPYLVLPLLGPSTLRDTAGLGVDYVGNPLTYVKPDGLS
HHHCCCCHHHHCEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
WGLFGVNLVNTRSNLLGAGDVLDAAALDKYSFVRNAYLQRRQMLISNARGEAAATSSNDA
ECEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPKYDLPEDGAAPAAAGTAGAAAVGGATAPAGASGAAVAAPASGTAESPNPASETNVPAM
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEE
QVAPPSPGGFRFPSIRLH
EECCCCCCCCCCCCEEEC
>Mature Secondary Structure
MQTIRIRQAALAVAAVAALSGCATVQTPTKGDPLEGFNRSMYKFNDTVDTYALKPVAKGY
CCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCC
QYVVPQPVRDSVTNFFSNIGDVYIAANNIVQLRIADGVGDIMRVVINTVFGVGGLFDVAT
EEECCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
IAKLPKHTADFGITMGRYGMPSGPYLVLPLLGPSTLRDTAGLGVDYVGNPLTYVKPDGLS
HHHCCCCHHHHCEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
WGLFGVNLVNTRSNLLGAGDVLDAAALDKYSFVRNAYLQRRQMLISNARGEAAATSSNDA
ECEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPKYDLPEDGAAPAAAGTAGAAAVGGATAPAGASGAAVAAPASGTAESPNPASETNVPAM
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEE
QVAPPSPGGFRFPSIRLH
EECCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]