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The map label for this gene is pilQ [H]

Identifier: 78064965

GI number: 78064965

Start: 351118

End: 352749

Strand: Direct

Name: pilQ [H]

Synonym: Bcep18194_A3488

Alternate gene names: 78064965

Gene position: 351118-352749 (Clockwise)

Preceding gene: 78064964

Following gene: 78064966

Centisome position: 9.5

GC content: 70.65

Gene sequence:

>1632_bases
ATGATGAAGCACGGATGTCGGGTGCTCGCCGTTTGGGCCGGATTGACCGCGGCCAGTGCAAGCGCGTCATTGCCGCCGCT
GCCGGCCGTCTGGCCTGCCGCAGCGTTGGATACGCAGGTGCCGGGCGTGCCGTTGCCACAAGGCGCGGTGGACGGTGCGG
ATCACACCGTCTCGACGGAGGCCGGCCCGCCGCCGTTCGACCAGGCGGCTCGCGCGGTGCTTCAAGCGGAAGCCACCACC
ACGGCAGCCGGGCTGGAGGGGCCGCCGATCCCGCTGGCGCCGCCGGCCCGGATGGGCGATGCTGCGGCCCGGCAACCGGG
CGATGCGGACGACACGCGGCGAATCTCGCTGAATCTGCAGGGCGCGGGGCTCGCGGCCGCGTTCGACGCGTTCGCGCGGT
TCACCGGACTCAATATCGTCGTCGGCGAGCAGGTGCGTGGCACCGTCACGTTACGTCTGAACAATGTGCGCTGGCGCGAT
GCCTTCGACACGCTGCTCGACACGCACGGGCTCGCGATGTCCCGGCGGGGCAGCGTGATATGGGTCACGCCGGCGGCCGA
GCTGGCCGCGCGCGAACGCGAGCGCTTCGAAATGCACGCGCGGGCCGCCGATCTGGAGCCGCTTGCGAGCCGGACCTTCG
CGCTGCACTACCCGCGCGCGCAGGACGTGCAACGGCTGCTGGCCGGCGCGACCGGCCAGCGCCTGCTGTCGAAGCGCGGC
GCCGCGGCGGCCGATCCGCGCACGAACCTGCTGTTCGTCACCGATCTCGCGCCGCGTCTCGATCAGGTCGCGAGCCTGAT
CGAGGCGATCGACCGGCCGTCGCGGCAAGTCCGGATCGAGGCCCGCATCGTCGAGGGCGAGCAGGGTTTTTCGCGCAATC
TCGGCGCGCGCGTCGCGCTGCGGGCGCAGGGGCGGCCGCCGTCGGGCGAGAGCGCCACGTTCACGACCGGTGCGCGCAAC
GCGCTCGACCTGGCTGCGCGGCCGCTCGGCGGCTTCGAAGCGGCAACCGCCGGCTTCACGCTGTTCGCCGCGCCGCTCAG
CCGTGTGCTCGACGTCGAACTGAGCGCGCTCGAGGCTCAGGGGCGGGGCCAGATCGTCTCGAGTCCGCGCGTGGTGACCG
CCGATCGCGTCAAGGCCATCGTCGAACAGGGTTCGGAGGTGCCGTACCAGGCGAAGGTCGGCAACGGCGTGAGCGGCGTG
CAGTTCCGCCGGGCGACGCTCAAACTGGAGGTCGAGCCCCAGATCACGCCAGACGGGCGCGTGGTACTCGACCTGGACGT
GACGAAGGACAGCATCGGCGAGCCGACGGCGGCCGGCCCGGCGATCCATACGAAACACGTCCAGACGCGTGTCGAGGTCG
AAAACGGCGGGACGGTGGCGATCGGCGGGATCTATGAGCAACTGAACAGGAACGATGTGACGCGCGTGCCGCTCTTGGGC
AAAATACCGTTTCTGGGCGCGCTTTTCCGGCACCGCGCGCAACGCGATCAGCGCAACGAACTGGTCGTCTTCATCACGCC
GACCGTCGTCGATGCGCGCTGCAATGAGCGCGGCGCGGCCGGTGCGGATGCCGAAAAAACAGGGCCGGAAGCCGCCGGCG
CAGGCTCGACAAGGCAGCCGCTTTGCCAGTAA

Upstream 100 bases:

>100_bases
CCCTCGGGGTCGCGCGGGTGGTGCGAGTCGATCCCGTCGCCGTGACGCTCGCGACGGCGGACGGCGCGTACCGCGTCACC
CTGGACGACGGGAGGCGGCC

Downstream 100 bases:

>100_bases
GCTGCGCCACACACCAGCAAGATTGAAGCAGAGGAAGCCGTTGCAAGCGCGGGACCCACATGCAAACGTATTTTTCGTCG
GCCTTATGGGAGCGGGTAAG

Product: type II and III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MMKHGCRVLAVWAGLTAASASASLPPLPAVWPAAALDTQVPGVPLPQGAVDGADHTVSTEAGPPPFDQAARAVLQAEATT
TAAGLEGPPIPLAPPARMGDAAARQPGDADDTRRISLNLQGAGLAAAFDAFARFTGLNIVVGEQVRGTVTLRLNNVRWRD
AFDTLLDTHGLAMSRRGSVIWVTPAAELAARERERFEMHARAADLEPLASRTFALHYPRAQDVQRLLAGATGQRLLSKRG
AAAADPRTNLLFVTDLAPRLDQVASLIEAIDRPSRQVRIEARIVEGEQGFSRNLGARVALRAQGRPPSGESATFTTGARN
ALDLAARPLGGFEAATAGFTLFAAPLSRVLDVELSALEAQGRGQIVSSPRVVTADRVKAIVEQGSEVPYQAKVGNGVSGV
QFRRATLKLEVEPQITPDGRVVLDLDVTKDSIGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCNERGAAGADAEKTGPEAAGAGSTRQPLCQ

Sequences:

>Translated_543_residues
MMKHGCRVLAVWAGLTAASASASLPPLPAVWPAAALDTQVPGVPLPQGAVDGADHTVSTEAGPPPFDQAARAVLQAEATT
TAAGLEGPPIPLAPPARMGDAAARQPGDADDTRRISLNLQGAGLAAAFDAFARFTGLNIVVGEQVRGTVTLRLNNVRWRD
AFDTLLDTHGLAMSRRGSVIWVTPAAELAARERERFEMHARAADLEPLASRTFALHYPRAQDVQRLLAGATGQRLLSKRG
AAAADPRTNLLFVTDLAPRLDQVASLIEAIDRPSRQVRIEARIVEGEQGFSRNLGARVALRAQGRPPSGESATFTTGARN
ALDLAARPLGGFEAATAGFTLFAAPLSRVLDVELSALEAQGRGQIVSSPRVVTADRVKAIVEQGSEVPYQAKVGNGVSGV
QFRRATLKLEVEPQITPDGRVVLDLDVTKDSIGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCNERGAAGADAEKTGPEAAGAGSTRQPLCQ
>Mature_543_residues
MMKHGCRVLAVWAGLTAASASASLPPLPAVWPAAALDTQVPGVPLPQGAVDGADHTVSTEAGPPPFDQAARAVLQAEATT
TAAGLEGPPIPLAPPARMGDAAARQPGDADDTRRISLNLQGAGLAAAFDAFARFTGLNIVVGEQVRGTVTLRLNNVRWRD
AFDTLLDTHGLAMSRRGSVIWVTPAAELAARERERFEMHARAADLEPLASRTFALHYPRAQDVQRLLAGATGQRLLSKRG
AAAADPRTNLLFVTDLAPRLDQVASLIEAIDRPSRQVRIEARIVEGEQGFSRNLGARVALRAQGRPPSGESATFTTGARN
ALDLAARPLGGFEAATAGFTLFAAPLSRVLDVELSALEAQGRGQIVSSPRVVTADRVKAIVEQGSEVPYQAKVGNGVSGV
QFRRATLKLEVEPQITPDGRVVLDLDVTKDSIGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCNERGAAGADAEKTGPEAAGAGSTRQPLCQ

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=410, Percent_Identity=33.6585365853659, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87082242, Length=378, Percent_Identity=27.2486772486773, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 57330; Mature: 57330

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKHGCRVLAVWAGLTAASASASLPPLPAVWPAAALDTQVPGVPLPQGAVDGADHTVSTE
CCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEECC
AGPPPFDQAARAVLQAEATTTAAGLEGPPIPLAPPARMGDAAARQPGDADDTRRISLNLQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEEC
GAGLAAAFDAFARFTGLNIVVGEQVRGTVTLRLNNVRWRDAFDTLLDTHGLAMSRRGSVI
CCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCEEHHHHHHHHHHHCCCEEECCCCEE
WVTPAAELAARERERFEMHARAADLEPLASRTFALHYPRAQDVQRLLAGATGQRLLSKRG
EEECHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHHHHHHHHCCHHHHHHHHCC
AAAADPRTNLLFVTDLAPRLDQVASLIEAIDRPSRQVRIEARIVEGEQGFSRNLGARVAL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEE
RAQGRPPSGESATFTTGARNALDLAARPLGGFEAATAGFTLFAAPLSRVLDVELSALEAQ
EECCCCCCCCCCEEECCCCHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GRGQIVSSPRVVTADRVKAIVEQGSEVPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGR
CCCCEECCCCEEEHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCC
VVLDLDVTKDSIGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
EEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECHHHHHCCCCCCEECCCCC
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCNERGAAGADAEKTGPEAAGAGSTRQP
CCHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LCQ
CCC
>Mature Secondary Structure
MMKHGCRVLAVWAGLTAASASASLPPLPAVWPAAALDTQVPGVPLPQGAVDGADHTVSTE
CCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEECC
AGPPPFDQAARAVLQAEATTTAAGLEGPPIPLAPPARMGDAAARQPGDADDTRRISLNLQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEEC
GAGLAAAFDAFARFTGLNIVVGEQVRGTVTLRLNNVRWRDAFDTLLDTHGLAMSRRGSVI
CCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCEEHHHHHHHHHHHCCCEEECCCCEE
WVTPAAELAARERERFEMHARAADLEPLASRTFALHYPRAQDVQRLLAGATGQRLLSKRG
EEECHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHHHHHHHHCCHHHHHHHHCC
AAAADPRTNLLFVTDLAPRLDQVASLIEAIDRPSRQVRIEARIVEGEQGFSRNLGARVAL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEE
RAQGRPPSGESATFTTGARNALDLAARPLGGFEAATAGFTLFAAPLSRVLDVELSALEAQ
EECCCCCCCCCCEEECCCCHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GRGQIVSSPRVVTADRVKAIVEQGSEVPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGR
CCCCEECCCCEEEHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCC
VVLDLDVTKDSIGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
EEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECHHHHHCCCCCCEECCCCC
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCNERGAAGADAEKTGPEAAGAGSTRQP
CCHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LCQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]