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The map label for this gene is aroK

Identifier: 78064966

GI number: 78064966

Start: 352790

End: 353344

Strand: Direct

Name: aroK

Synonym: Bcep18194_A3489

Alternate gene names: 78064966

Gene position: 352790-353344 (Clockwise)

Preceding gene: 78064965

Following gene: 78064967

Centisome position: 9.55

GC content: 63.06

Gene sequence:

>555_bases
TTGCAAGCGCGGGACCCACATGCAAACGTATTTTTCGTCGGCCTTATGGGAGCGGGTAAGACCACCGTGGGCCGTGCGGT
CGCGCGTCGTCTCGACAGGACGTTCTTCGACTCCGACCACGAAATCGAGGCCCGTACGGGCGCGCGCATCCCGGTGATCT
TCGAGATGGAGGGCGAGGCCGGGTTTCGCGATCGCGAAACGCAGGTGATCACCGATCTCACGCAGCGCGAGAATATCGTG
CTCGCGACGGGCGGCGGCGCGGTGCTGCGCCCGGAAAACCGCGACTGTCTGAAAAACAACGGCATCGTCGTCTACCTGCG
CGCCAATCCGCACGATCTGTGGCTGCGTACCCGCAAGGACAAGAACCGCCCGCTGCTGCAGACCGAAGATCCGAAGGGGC
GTCTCGAAGCGCTGTACGAGGTACGAGACCCGCTGTACCGCGAATGCGCGGATTTCGTCATCGAGACCGGCCGTCCGTCG
GTCAACGGTCTCGTCAACATGGTGCTGATGCAACTCGAACTGGCCGGCGTCATCGCCAAGCCGCTACAAGCATGA

Upstream 100 bases:

>100_bases
GAAAAAACAGGGCCGGAAGCCGCCGGCGCAGGCTCGACAAGGCAGCCGCTTTGCCAGTAAGCTGCGCCACACACCAGCAA
GATTGAAGCAGAGGAAGCCG

Downstream 100 bases:

>100_bases
TTACTGTCAACGTCGATCTGGGCGACCGCGCCTATCCGATTCACATTGGCGCCGGCCTGATCGGCCGCGCCGAGTTGTTC
GCGCCTCACATCAAGGGCTC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEAGFRDRETQVITDLTQRENIV
LATGGGAVLRPENRDCLKNNGIVVYLRANPHDLWLRTRKDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA

Sequences:

>Translated_184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEAGFRDRETQVITDLTQRENIV
LATGGGAVLRPENRDCLKNNGIVVYLRANPHDLWLRTRKDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA
>Mature_184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEAGFRDRETQVITDLTQRENIV
LATGGGAVLRPENRDCLKNNGIVVYLRANPHDLWLRTRKDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=50, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786587, Length=155, Percent_Identity=40, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_BURS3 (Q39KC5)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_367735.1
- ProteinModelPortal:   Q39KC5
- SMR:   Q39KC5
- STRING:   Q39KC5
- GeneID:   3748666
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A3489
- NMPDR:   fig|269483.3.peg.4763
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- ProtClustDB:   PRK00131
- BioCyc:   BSP36773:BCEP18194_A3489-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20670; Mature: 20670

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS01128 SHIKIMATE_KINASE; PS00267 TACHYKININ

Important sites: BINDING 39-39 BINDING 63-63 BINDING 85-85 BINDING 123-123 BINDING 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCC
GFRDRETQVITDLTQRENIVLATGGGAVLRPENRDCLKNNGIVVYLRANPHDLWLRTRKD
CCCCCCHHHHHHHHCCCCEEEEECCCEEECCCCCHHHCCCCEEEEEECCCCEEEEEECCC
KNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPSVNGLVNMVLMQLELAGVIAK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PLQA
CCCC
>Mature Secondary Structure
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCC
GFRDRETQVITDLTQRENIVLATGGGAVLRPENRDCLKNNGIVVYLRANPHDLWLRTRKD
CCCCCCHHHHHHHHCCCCEEEEECCCEEECCCCCHHHCCCCEEEEEECCCCEEEEEECCC
KNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPSVNGLVNMVLMQLELAGVIAK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PLQA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA