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The map label for this gene is recQ [H]

Identifier: 78064918

GI number: 78064918

Start: 315053

End: 316900

Strand: Direct

Name: recQ [H]

Synonym: Bcep18194_A3441

Alternate gene names: 78064918

Gene position: 315053-316900 (Clockwise)

Preceding gene: 78064917

Following gene: 78064919

Centisome position: 8.53

GC content: 67.53

Gene sequence:

>1848_bases
ATGTCCCGCGCCCTCGAAATCCTCGACGAAGTATTTGGTTATCCCGCATTTCGCGGCCAGCAGGGCGAGATCGTCGAGCA
CGTCGCCGGCGGCGGCGATTGCCTCGTGCTGATGCCGACCGGCGGCGGCAAGTCGTTGTGCTACCAGATTCCGGCGCTGC
TGCGCCGCGAGGCCGGGCAGGGCGCCGGCATCGTCGTGTCGCCGTTGATCGCGCTGATGCAGGACCAGGTCGCCGCACTG
AGGGAAGTGGGCGTGCGCGCCGCGTACCTGAATTCGACGCTGTCGGGTGCCGAGGCCGCGGCGACCGAGCGCGCGCTGCG
CGAAGGTGAAATCGATCTGCTCTACGTCGCGCCGGAACGCCTGATGACGGGGCGCTTCCTCGACCTGATCGAGCGCGCGA
AGATCGGGCTGTTCGCGATCGACGAAGCGCACTGCGTGTCGCAATGGGGGCACGATTTCCGTCCGGAATACATCCAGCTG
TCGGTGCTGCACGAGCGATTCCCGTCGGTGCCGCGCATCGCACTGACCGCCACGGCCGATGCGATCACGCGCGACGAGAT
CATCCATCGCCTCGCGCTCGACGACGCGCGCGTGTTCGTGTCGAGCTTCGACCGCCCGAACATCCGCTACCGGATCGTCG
AAAAGGACAACGCGCGGTCGCAGCTGCTCGATTTCATCCGCGCCGAACACACGAATGCCGACGGCACGACGGATGCGGGC
GTCGTCTATTGCCTGTCGCGCCGCAAGGTCGAGGAAACGGCCGAATGGCTGAAGGCGCAGGGCGTGCGCGCGCTGCCGTA
TCACGCGGGGATGGAGTTCGAGGTGCGGCAAAAGCACCAGGAAATGTTCCAGCGCGAGGAGGGCATCGTGATGTGCGCGA
CGATCGCGTTCGGCATGGGCATCGACAAGCCGGACGTGCGCTTCGTCGCGCACCTGGATCTGCCGAAGAGCGTCGAAGGC
TACTACCAGGAAACGGGCCGCGCCGGCCGCGACGGGATGCCCGCGAATGCGTGGATGGCGTACGGTCTGGGCGACGTCGT
CCAGCAGCGCAAGATGATCGATGAGTCCGATGCGGACGACGCGCACAAGCGCGTCCAGACGTCGAAGCTCGACGCGCTGC
TCGGGCTGTGCGAGACGATCTCGTGCCGTCGCGTGCGGCTGTTGAACTACTTCGGCGAGGAGAGCAAGCCGTGCGGCAAC
TGCGACACCTGCATCGAGCCGCCGGCTTCGTGGGACGCCACGCGTGAAGCGCAGATGGCGCTGTCCTGCGTGTTCCGCGC
GCAGCGCGCGAGCGGTTTCAATTTCGGCTCGAGCCACCTGATCGAGATCCTGCGCGGCGGGCGCACCGAGAAGGTGTTGC
AGCGCGGCCACGACCAGCTCACGACGTTCGGGATCGGCGCGTCGCTGTCGGAACCCGAGTGGCGCGCGATTTTCCGTCAG
CTCGTCGCGTACGGCTTCCTGGCCGTCGATCACGGCGGCTTCGGCGCGCTCGTGCTGACCGAGGCCGCGAAGCCCGTGCT
GAAGAACGAGGAGAAGGTCACGCTGCGCCGCTACGTGAAGCCGCAGCGCACGCGCCAGTCGTCGAGCCGCAGCGGTACGC
GCGTCGATCCGACGGCCGGCATGGGCACGCGTGAGCGCGCACGGTGGGATGCGCTGCGCGCCTGGCGTGCGGAAACGGCG
AAGACGGACGGCGTGCCGGCCTACGTGATCTTCCACGATGCGACGCTCGCCGAGATCGCGCGCAACGCGCCGGAGTCGAT
CGACGACCTGCGCCATATCCCCGGCATGGGCGTGCGCAAGCTGGAGCGCTTCGGCGACGAGATCATCGACGTCGTCGAAT
CGGCCTGA

Upstream 100 bases:

>100_bases
ACGAACCTGGCCGATCGGCCAAATCCGCACGATTCGCCACGCGTCGCGCGAGCGGGTTGTTAAAATTGCGGTCACCGTTT
AGCCGTCCCAGTCCTCATTC

Downstream 100 bases:

>100_bases
CACAGGCGTTCCGACCCTTCCGGTAAACCACACGTTCGGCTGGCGAATCACGCAAGCCGTTGACTTAGTTGGTATTTCCG
GAATATGATGCTGGGTTCCG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MSRALEILDEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQGAGIVVSPLIALMQDQVAAL
REVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLDLIERAKIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPSVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEESKPCGN
CDTCIEPPASWDATREAQMALSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLTTFGIGASLSEPEWRAIFRQ
LVAYGFLAVDHGGFGALVLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAGMGTRERARWDALRAWRAETA
KTDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGMGVRKLERFGDEIIDVVESA

Sequences:

>Translated_615_residues
MSRALEILDEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQGAGIVVSPLIALMQDQVAAL
REVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLDLIERAKIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPSVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEESKPCGN
CDTCIEPPASWDATREAQMALSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLTTFGIGASLSEPEWRAIFRQ
LVAYGFLAVDHGGFGALVLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAGMGTRERARWDALRAWRAETA
KTDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGMGVRKLERFGDEIIDVVESA
>Mature_614_residues
SRALEILDEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQGAGIVVSPLIALMQDQVAALR
EVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLDLIERAKIGLFAIDEAHCVSQWGHDFRPEYIQLS
VLHERFPSVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAGV
VYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGY
YQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEESKPCGNC
DTCIEPPASWDATREAQMALSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLTTFGIGASLSEPEWRAIFRQL
VAYGFLAVDHGGFGALVLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAGMGTRERARWDALRAWRAETAK
TDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGMGVRKLERFGDEIIDVVESA

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=654, Percent_Identity=34.4036697247706, Blast_Score=352, Evalue=5e-97,
Organism=Homo sapiens, GI14591902, Length=417, Percent_Identity=37.8896882494005, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI14591904, Length=417, Percent_Identity=37.8896882494005, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI148612816, Length=474, Percent_Identity=37.5527426160338, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI51242943, Length=401, Percent_Identity=39.1521197007481, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI51242947, Length=401, Percent_Identity=39.1521197007481, Blast_Score=256, Evalue=5e-68,
Organism=Homo sapiens, GI169218196, Length=593, Percent_Identity=30.8600337268128, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI110735439, Length=509, Percent_Identity=33.3988212180747, Blast_Score=249, Evalue=6e-66,
Organism=Homo sapiens, GI284005309, Length=347, Percent_Identity=35.7348703170029, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI148613856, Length=370, Percent_Identity=24.5945945945946, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38201710, Length=370, Percent_Identity=24.5945945945946, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=618, Percent_Identity=44.336569579288, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI87082221, Length=356, Percent_Identity=25.561797752809, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=514, Percent_Identity=38.9105058365759, Blast_Score=331, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI71987997, Length=412, Percent_Identity=40.0485436893204, Blast_Score=298, Evalue=6e-81,
Organism=Caenorhabditis elegans, GI71987993, Length=412, Percent_Identity=40.0485436893204, Blast_Score=298, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI32564293, Length=672, Percent_Identity=31.25, Blast_Score=288, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17552866, Length=496, Percent_Identity=35.2822580645161, Blast_Score=254, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI71995718, Length=337, Percent_Identity=25.2225519287834, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17510309, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17510307, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71995514, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=348, Percent_Identity=23.2758620689655, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=542, Percent_Identity=35.7933579335793, Blast_Score=349, Evalue=8e-97,
Organism=Saccharomyces cerevisiae, GI6324778, Length=338, Percent_Identity=25.1479289940828, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325138, Length=336, Percent_Identity=24.702380952381, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646066, Length=508, Percent_Identity=40.3543307086614, Blast_Score=355, Evalue=4e-98,
Organism=Drosophila melanogaster, GI24664226, Length=441, Percent_Identity=37.4149659863946, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24664230, Length=432, Percent_Identity=37.7314814814815, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI62472181, Length=432, Percent_Identity=37.7314814814815, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI21358123, Length=355, Percent_Identity=35.2112676056338, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI28574962, Length=377, Percent_Identity=23.8726790450928, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68221; Mature: 68090

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRALEILDEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQ
CCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
GAGIVVSPLIALMQDQVAALREVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHH
LMTGRFLDLIERAKIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPSVPRIALTATAD
HHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECHH
AITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTSKLDALLGLCETISCRRVRLLNYFGEESKPCGNCDTCIEPPASWDATREAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLTTFGIGASLSEPEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHEEEECCCCCCCHHHHHHHHH
LVAYGFLAVDHGGFGALVLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAG
HHHHHEEEEECCCCCEEEEEHHHHHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCC
MGTRERARWDALRAWRAETAKTDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGMGVRK
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHCCCCCHHH
LERFGDEIIDVVESA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRALEILDEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQ
CHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
GAGIVVSPLIALMQDQVAALREVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHH
LMTGRFLDLIERAKIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPSVPRIALTATAD
HHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECHH
AITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTSKLDALLGLCETISCRRVRLLNYFGEESKPCGNCDTCIEPPASWDATREAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLTTFGIGASLSEPEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHEEEECCCCCCCHHHHHHHHH
LVAYGFLAVDHGGFGALVLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAG
HHHHHEEEEECCCCCEEEEEHHHHHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCC
MGTRERARWDALRAWRAETAKTDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGMGVRK
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHCCCCCHHH
LERFGDEIIDVVESA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]