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The map label for this gene is rpoC

Identifier: 78064917

GI number: 78064917

Start: 310547

End: 314791

Strand: Direct

Name: rpoC

Synonym: Bcep18194_A3440

Alternate gene names: 78064917

Gene position: 310547-314791 (Clockwise)

Preceding gene: 78064916

Following gene: 78064918

Centisome position: 8.41

GC content: 62.14

Gene sequence:

>4245_bases
ATGAAAGCTCTGCTCGATCTATTCAAGCAAGTCCAACAGGAAGAAGTTTTCGACGCGATCAAGATCGGTCTGGCCTCGCC
GGACAAGATCCGTTCGTGGTCGTTCGGCGAAGTGAAGAAGCCGGAGACCATCAACTACCGTACGTTCAAGCCGGAACGCG
ATGGTCTCTTCTGCGCGAAGATCTTCGGGCCGATCAAGGACTACGAGTGCCTGTGCGGCAAGTACAAGCGTCTGAAGCAC
CGCGGCGTGATCTGCGAGAAGTGCGGCGTCGAAGTGACGCTGGCGAAGGTGCGTCGCGAACGGATGGGCCACATCGAGCT
GGCCTCGCCGGTCGCTCACATCTGGTTCCTGAAGTCGCTGCCGTCGCGTCTGGGCATGGTGCTCGACATGACGCTGCGCG
ACATCGAACGCGTGCTGTACTTCGAAGCCTATGTGGTGATCGAACCGGGCATGACGCCGCTGAAGGCGCGGCAGATCATG
ACCGAAGAGGATTACTACAACAAGGTCGAGGAATACGGCGACGAATTCCGTGCCGAAATGGGCGCGGAAGGCGTGCGTGA
ACTGCTGCGCGCGATCAACATCGACGAGCAGGTCGAGACGCTGCGCACCGAGCTGAAGAACACCGGCTCGGAAGCGAAGA
TCAAGAAGTACGCGAAGCGCCTGAAGGTCCTCGAGGCATTCCAGCGCTCGGGCATCAAGCCCGAGTGGATGATCCTCGAA
GTGCTGCCGGTGCTGCCGCCGGAACTGCGTCCGCTCGTGCCGCTGGACGGTGGCCGTTTCGCGACGTCGGACCTGAACGA
CCTGTATCGCCGCGTGATCAACCGTAACAACCGGTTGAAGCGTCTGCTCGAGCTGAAGGCGCCTGAAATCATCGTCCGCA
ACGAAAAGCGGATGCTGCAGGAAGCCGTCGACTCGCTGCTCGACAACGGTCGTCGCGGCAAGGCGATGACGGGTGCGAAC
AAGCGTCCGCTGAAGTCGCTCGCCGACATGATCAAGGGTAAGGGCGGTCGTTTCCGTCAGAACCTGCTGGGCAAGCGCGT
CGACTACTCGGGCCGTTCGGTCATCGTGGTCGGCCCGACGCTGAAGCTGCACCAGTGCGGTCTGCCGAAGCTGATGGCGC
TCGAACTGTTCAAGCCGTTCATCTTCAACAAGCTGGAAGTGATGGGCGTTGCGACGACCATCAAGGCTGCGAAGAAGGAA
GTCGAGAACCAGACGGCTGTGGTGTGGGACATCCTCGAAGAGGTGATCCGCGAGCACCCGGTGATGCTGAACCGTGCGCC
GACGCTGCACCGTCTCGGTATCCAGGCATTTGAGCCGGTGCTGATCGAAGGCAAGGCAATTCAGCTGCACCCGCTCGTCT
GCGCGGCGTTCAACGCCGACTTCGACGGTGACCAGATGGCCGTTCACGTGCCGCTGTCGCTCGAAGCGCAGATGGAAGCG
CGTACGCTGATGCTGGCGTCGAACAACGTCCTGTTCCCGGCCAACGGCGATCCGTCGATCGTGCCGTCGCAGGATATCGT
GCTGGGTCTGTACTACGCGACCCGCGAAGCGGTCAACGGCAAGGGCGAAGGCCTGTCGTTCACGGGCGTGTCGGAAGTGA
TCCGCGCGTACGAGAACAAGGAAGTCGAGCTCGCATCGCGCGTCAACGTGCGGATCACCGAAATGGTCCACAACGAAGAC
ACGTCGGAAGGCGCACCGCCGTTCGTGCCGAAGATCTCGCTGTACGCGACGACCGTCGGTCGCGCGATCCTGTCGGAGAT
CCTGCCGCACGGCCTGCCGTTCTCGGTGCTGAACAAGCCGCTGAAGAAGAAGGAAATCTCGCGCCTGATCAACACGGCGT
TCCGCAAGTGCGGTCTGCGCGCGACGGTGGTGTTTGCCGACCAGCTGATGCAGTCGGGTTTCCGTCTCGCGACGCGTGCC
GGCATCTCGATCTGCGTGGACGACATGCTCGTGCCGCCGCAGAAGGAAACGATCGTCGGCGACGCCGCGAAGAAGGTGAA
GGAGTACGACCGTCAGTACATGTCGGGTCTCGTCACCGCGCAGGAACGCTACAACAACGTGGTCGACATCTGGTCGGCAA
CGTCGGAAGCGGTCGGCAAGGCGATGATGGAGCAGCTGTCGACGGAGCCGGTGACGGACCGCGACGGCAAGGAAACGCGC
CAGGAATCGTTCAACTCGATCTACATGATGGCCGACTCGGGCGCCCGGGGTTCGGCGGTTCAGATTCGTCAGCTGGCCGG
TATGCGAGGCCTGATGGCGAAGCCGGACGGCTCGATTATCGAGACGCCGATTACCGCGAACTTCCGCGAAGGTCTGAACG
TGTTGCAGTACTTCATCTCGACCCACGGTGCACGTAAGGGTCTGGCTGATACGGCACTGAAGACCGCGAACTCGGGTTAC
CTGACGCGTCGTCTCGTCGACGTCACGCAGGATCTGGTCGTGGTGGAAGACGATTGCGGCACGTCGAACGGCGTGGCGAT
GAAGGCACTCGTCGAAGGCGGTGAAGTCGTCGAAGCGCTGCGTGACCGTATCCTCGGCCGCGTTGCGGTTGCGGACGTCG
TGAACCCGGAAACGCAGGAAACGGTGTACGAATCGGGCACGCTGCTCGACGAAACGGCGGTCGAGGAAATCGAACGCCTC
GGCATCGACGAAGTGCGCGTTCGCACGCCGCTGACCTGCGAAACGCGTTACGGCCTGTGCGCAGCCTGCTACGGCCGTGA
CCTCGGCCGCGGCTCGCTCGTGAACGTCGGCGAAGCAGTCGGCGTGATCGCGGCACAGTCGATCGGTGAACCGGGCACGC
AGCTGACGATGCGTACGTTCCACATCGGTGGTGCGGCATCGCGTGCGGCAGTGGCTTCGTCGGTCGAAGCGAAGAGCAAC
GGTATCGTCCGCTTCACGGCGACGATGCGCTACGTTACGAACGCGAAGGGCGAGCAGATCGTCATTTCCCGTTCGGGCGA
AGCGATGATCACCGACGACTTCGGTCGCGAGCGCGAGCGTCACAAAGTGCCGTACGGCGCGACGCTGCTGCAGCTCGACG
GCGTGACGATCAAGGCAGGCACGCAGCTCGCCACGTGGGATCCGCTGACGCGTCCGATCATCACCGAGTACGGTGGTACG
GTGAAGTTCGAGAACGTCGAGGAAGGCGTGACCGTCGCGAAGCAGATCGACGACGTGACCGGCCTGTCGACGCTGGTCGT
GATCGACGTGAAGCGTCGTGGCTCGCAAGCTTCGAAGAGCGTGCGTCCGCAGGTCAAGCTGCTCGACGCGAACGGCGACG
AAGTGAAGATTCCGGGCACGGAGCACGCAGTGCAGATCGGCTTCCAGGTCGGCGCACTGATCACCGTGAAGGATGGCCAG
CAGGTGCAGGTCGGTGAAGTGCTTGCACGTATCCCGACGGAAGCGCAGAAGACGCGTGACATTACCGGCGGTCTGCCGCG
GGTGGCGGAACTGTTCGAAGCGCGTTCGCCGAAGGATGCCGGCATTCTCGCGGAAGTCACCGGTACGACGTCGTTCGGTA
AGGATACGAAGGGCAAGCAGCGTCTCGTCATCACGGACCTCGAGGGCAACCAGCACGAGTTCCTGATCGCGAAGGAAAAG
CAGGTTCTGGTTCACGATGCTCAGGTCGTCAACAAGGGCGAAATGATCGTGGACGGTCCGGCCGATCCGCACGACATCCT
GCGTCTGCAGGGTATCGAGGCGCTGTCGCGCTACATCGTCGACGAAGTGCAGGACGTGTATCGTCTGCAGGGCGTGAAGA
TCAACGACAAGCACATCGAGGTGATCGTTCGCCAGATGCTGCGTCGTGTGCAGATCACCGACAACGGTGATACGCGCTTC
ATCCCGGGCGAACAGGTCGAGCGTTCCGACATGCTGGACGAGAACGATCGCATGATCGCCGAGGACAAGCGTCCGGCTTC
GTACGACAACGTGCTGCTCGGTATCACGAAGGCATCGCTGTCGACCGACTCGTTCATCTCCGCGGCATCGTTCCAGGAAA
CGACCCGCGTGCTGACCGAAGCGGCGATCATGGGCAAGCGCGACGATCTGCGTGGCCTGAAGGAAAACGTGATCGTCGGC
CGTCTGATTCCGGCCGGTACGGGTCTCGCGTTCCACAAGGCACGCAAGGCGAAGGAATCGTCGGATCGCGAGCGTTTCGA
CCAGATCGCAGCGGAAGAGGCATTCGACTTCGGCACGCCGAGCGCGCCGGCAGAAGAGCCGCAGCAACACCCGGCAGCCG
AGTAA

Upstream 100 bases:

>100_bases
AGGCATGCCGGAATCCTTCAACGTGCTCGTGAAGGAAATCCGCTCGCTCGGTATCGACATCGATCTCGACCGCAATTAAT
CGGACTACGGAGAGAAAGCA

Downstream 100 bases:

>100_bases
GCGCGGGCGGCGCGAGCCGCCTTGCCTTACCTCGCTGTCACCGAAACCGCCCGGTTCTGCCGGGCGGTTTTTTTTCATCT
GTCGTTCACGCGCATGACGA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1414; Mature: 1414

Protein sequence:

>1414_residues
MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIM
TEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKE
VENQTAVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVHNED
TSEGAPPFVPKISLYATTVGRAILSEILPHGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRA
GISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGKETR
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGY
LTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAVADVVNPETQETVYESGTLLDETAVEEIERL
GIDEVRVRTPLTCETRYGLCAACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
GIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGVTIKAGTQLATWDPLTRPIITEYGGT
VKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKSVRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQ
QVQVGEVLARIPTEAQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
QVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRF
IPGEQVERSDMLDENDRMIAEDKRPASYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVG
RLIPAGTGLAFHKARKAKESSDRERFDQIAAEEAFDFGTPSAPAEEPQQHPAAE

Sequences:

>Translated_1414_residues
MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIM
TEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKE
VENQTAVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVHNED
TSEGAPPFVPKISLYATTVGRAILSEILPHGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRA
GISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGKETR
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGY
LTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAVADVVNPETQETVYESGTLLDETAVEEIERL
GIDEVRVRTPLTCETRYGLCAACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
GIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGVTIKAGTQLATWDPLTRPIITEYGGT
VKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKSVRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQ
QVQVGEVLARIPTEAQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
QVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRF
IPGEQVERSDMLDENDRMIAEDKRPASYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVG
RLIPAGTGLAFHKARKAKESSDRERFDQIAAEEAFDFGTPSAPAEEPQQHPAAE
>Mature_1414_residues
MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIM
TEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKE
VENQTAVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVHNED
TSEGAPPFVPKISLYATTVGRAILSEILPHGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRA
GISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGKETR
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGY
LTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAVADVVNPETQETVYESGTLLDETAVEEIERL
GIDEVRVRTPLTCETRYGLCAACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
GIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGVTIKAGTQLATWDPLTRPIITEYGGT
VKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKSVRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQ
QVQVGEVLARIPTEAQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
QVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRF
IPGEQVERSDMLDENDRMIAEDKRPASYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVG
RLIPAGTGLAFHKARKAKESSDRERFDQIAAEEAFDFGTPSAPAEEPQQHPAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=942, Percent_Identity=23.6730360934183, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI39725938, Length=489, Percent_Identity=25.3578732106339, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI103471997, Length=227, Percent_Identity=30.3964757709251, Blast_Score=87, Evalue=1e-16,
Organism=Escherichia coli, GI2367335, Length=1396, Percent_Identity=66.0458452722063, Blast_Score=1871, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=932, Percent_Identity=24.5708154506438, Blast_Score=174, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI25145495, Length=498, Percent_Identity=25.1004016064257, Blast_Score=135, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320061, Length=888, Percent_Identity=23.9864864864865, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=728, Percent_Identity=24.5879120879121, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17530899, Length=919, Percent_Identity=23.2861806311208, Blast_Score=170, Evalue=8e-42,
Organism=Drosophila melanogaster, GI281360912, Length=503, Percent_Identity=24.4532803180915, Blast_Score=122, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_BURS3 (Q39KH4)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_367686.1
- ProteinModelPortal:   Q39KH4
- STRING:   Q39KH4
- GeneID:   3748617
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A3440
- NMPDR:   fig|269483.3.peg.4655
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- BioCyc:   BSP36773:BCEP18194_A3440-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 156265; Mature: 156265

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEHH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEM
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHH
GAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILE
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHHH
EAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPT
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCC
LKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTAVVWDILEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCHHH
RTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNGKGEGLSFTGVSEVIRAYENK
EEEEEECCCEEEECCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCEEECCHHHHHHHHCCC
EVELASRVNVRITEMVHNEDTSEGAPPFVPKISLYATTVGRAILSEILPHGLPFSVLNKP
CEEEHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
LKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVG
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHCCCCEEHHCCCCCCCCHHHHH
DAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGKETR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHH
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFIS
HHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
THGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEAL
HCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHHH
RDRILGRVAVADVVNPETQETVYESGTLLDETAVEEIERLGIDEVRVRTPLTCETRYGLC
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCEECCCCCHH
AACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
GIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGVTIKAG
CEEEEEEEEHHHHCCCCCEEEEECCCCEEEECCCCCCHHHCCCCCCCEEEEECCEEEECC
TQLATWDPLTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKS
CEEECCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHC
VRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQQVQVGEVLARIPTEAQKTRD
CCCEEEEEECCCCEEECCCCCCCEEEEEEEEEEEEECCCCEEHHHHHHHHCCCHHHHHHH
ITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
HCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
QVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIE
EEEEEHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPASYDNVLLGITKASL
HHHHHHHHHEEECCCCCEECCCCCCCCHHHCCCCCCCEEECCCCCCCCCCEEEEEEECCC
STDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKAKES
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCC
SDRERFDQIAAEEAFDFGTPSAPAEEPQQHPAAE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEHH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEM
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHH
GAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILE
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHHH
EAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPT
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCC
LKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTAVVWDILEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCHHH
RTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNGKGEGLSFTGVSEVIRAYENK
EEEEEECCCEEEECCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCEEECCHHHHHHHHCCC
EVELASRVNVRITEMVHNEDTSEGAPPFVPKISLYATTVGRAILSEILPHGLPFSVLNKP
CEEEHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
LKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVG
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHCCCCEEHHCCCCCCCCHHHHH
DAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGKETR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHH
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFIS
HHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
THGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEAL
HCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHHH
RDRILGRVAVADVVNPETQETVYESGTLLDETAVEEIERLGIDEVRVRTPLTCETRYGLC
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCEECCCCCHH
AACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
GIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGVTIKAG
CEEEEEEEEHHHHCCCCCEEEEECCCCEEEECCCCCCHHHCCCCCCCEEEEECCEEEECC
TQLATWDPLTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKS
CEEECCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHC
VRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQQVQVGEVLARIPTEAQKTRD
CCCEEEEEECCCCEEECCCCCCCEEEEEEEEEEEEECCCCEEHHHHHHHHCCCHHHHHHH
ITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
HCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
QVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIE
EEEEEHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPASYDNVLLGITKASL
HHHHHHHHHEEECCCCCEECCCCCCCCHHHCCCCCCCEEECCCCCCCCCCEEEEEEECCC
STDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKAKES
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCC
SDRERFDQIAAEEAFDFGTPSAPAEEPQQHPAAE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA