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The map label for this gene is czcR [H]

Identifier: 78064886

GI number: 78064886

Start: 267347

End: 268276

Strand: Direct

Name: czcR [H]

Synonym: Bcep18194_A3409

Alternate gene names: 78064886

Gene position: 267347-268276 (Clockwise)

Preceding gene: 78064884

Following gene: 78064894

Centisome position: 7.24

GC content: 72.04

Gene sequence:

>930_bases
TTGAATACGCGTGATCTCCAGGCATTCGTCGCGGTGGTCGACAGCGGGTCGATGGTGGCCGCGGCCGCGAAGCTCCACCT
GACGCAGCCGGGCCTGACGCGGCGCGTGCAGAACCTCGAAACGCTGCTCGGCATGCCGCTGCTCGAACGGCAAAGCAAGC
CGCTGAAGCCGACCGCCGCCGGGCGCGACGTCTACGCGCTTGCGCGCAACGTGCTGGGCGCGGTCGACGAGCTGATGGCG
GCGGGCGCGCCGGACAGCGAGCCGTCGGGCGAGCTGCGCATCGGCGTGCCGCCGTTCCTGTCCGAGCTGGCGCTCGAGCA
GCCGATCGACCGGCTGCGCGACGCGTTTCCACGCCTCACGCTGCGCGTGACGGCCGGCTGGTCGCCGGCCCTGATGCAGG
GCGTCGAGCGCGGCGCGCTCGACGTCGCGGCCGTGATGGTGCCGGCCAGTTCGACACTGCCCGACACGTTCGCGTCGACG
CTGCTCGGCACGCAGCCGACGGTGCTCGTCGCCGCGCGCGACTATCCGCTGCCGGACGGTCCGCTGTCGATCGACACGCT
GTCGGGTTTCCCGTGGGTGCTGAGCCAGGACGGCTGCGGGATGCGCTCGGCGCTGAGCCGCATGCTCGGCGCGGCCGGGC
TGCCGTTCGACGTCGCGGTCGAGGCGTTCGGTTCGGAGCTGCAGCTGTCGCTCGTCGCGCGCGGCGCCGGCATCGGCATT
GCGGCACCGAACGCGCTGGCGCGCAGCGCGCATCGCGATGCACTGAGGGTGGTGGAAACGGTGGGGCTGGAGACGCGGAT
CAACGTGTGGATCGTGCACGGCGCGCTGCCGGGCCGGCTGGTGCGGCCCGTCGCGCTGCTGCGCGATGCGCTCGGCGAAG
TGCTCGACGGGGAAAACAGGGTGGGGTCAGATGCAGTGAAAGCGATCTAG

Upstream 100 bases:

>100_bases
CATCGGAAGCCTGGCGAATGGGTCGAAGGAGTACCCATCGTAGGTGCCTGATGTTTATGCGACAATTGAAATATCTCTAA
CATGATTATGCGAGTTTGTT

Downstream 100 bases:

>100_bases
AGGCGACATTCGAGGGAAAATCCTTATTTTCTCTACGGAAATGTTGCATTGCGGAAACCGATTCGCTATAGTTGCACCTG
TCTCCTCCATGTCTCCTCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNTRDLQAFVAVVDSGSMVAAAAKLHLTQPGLTRRVQNLETLLGMPLLERQSKPLKPTAAGRDVYALARNVLGAVDELMA
AGAPDSEPSGELRIGVPPFLSELALEQPIDRLRDAFPRLTLRVTAGWSPALMQGVERGALDVAAVMVPASSTLPDTFAST
LLGTQPTVLVAARDYPLPDGPLSIDTLSGFPWVLSQDGCGMRSALSRMLGAAGLPFDVAVEAFGSELQLSLVARGAGIGI
AAPNALARSAHRDALRVVETVGLETRINVWIVHGALPGRLVRPVALLRDALGEVLDGENRVGSDAVKAI

Sequences:

>Translated_309_residues
MNTRDLQAFVAVVDSGSMVAAAAKLHLTQPGLTRRVQNLETLLGMPLLERQSKPLKPTAAGRDVYALARNVLGAVDELMA
AGAPDSEPSGELRIGVPPFLSELALEQPIDRLRDAFPRLTLRVTAGWSPALMQGVERGALDVAAVMVPASSTLPDTFAST
LLGTQPTVLVAARDYPLPDGPLSIDTLSGFPWVLSQDGCGMRSALSRMLGAAGLPFDVAVEAFGSELQLSLVARGAGIGI
AAPNALARSAHRDALRVVETVGLETRINVWIVHGALPGRLVRPVALLRDALGEVLDGENRVGSDAVKAI
>Mature_309_residues
MNTRDLQAFVAVVDSGSMVAAAAKLHLTQPGLTRRVQNLETLLGMPLLERQSKPLKPTAAGRDVYALARNVLGAVDELMA
AGAPDSEPSGELRIGVPPFLSELALEQPIDRLRDAFPRLTLRVTAGWSPALMQGVERGALDVAAVMVPASSTLPDTFAST
LLGTQPTVLVAARDYPLPDGPLSIDTLSGFPWVLSQDGCGMRSALSRMLGAAGLPFDVAVEAFGSELQLSLVARGAGIGI
AAPNALARSAHRDALRVVETVGLETRINVWIVHGALPGRLVRPVALLRDALGEVLDGENRVGSDAVKAI

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=275, Percent_Identity=27.6363636363636, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788481, Length=256, Percent_Identity=28.125, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787530, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=282, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787879, Length=202, Percent_Identity=28.2178217821782, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789506, Length=224, Percent_Identity=25, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787806, Length=155, Percent_Identity=29.6774193548387, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788297, Length=147, Percent_Identity=31.2925170068027, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789204, Length=252, Percent_Identity=24.2063492063492, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=179, Percent_Identity=29.608938547486, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788296, Length=229, Percent_Identity=24.4541484716157, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32409; Mature: 32409

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRDLQAFVAVVDSGSMVAAAAKLHLTQPGLTRRVQNLETLLGMPLLERQSKPLKPTAA
CCCHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
GRDVYALARNVLGAVDELMAAGAPDSEPSGELRIGVPPFLSELALEQPIDRLRDAFPRLT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEE
LRVTAGWSPALMQGVERGALDVAAVMVPASSTLPDTFASTLLGTQPTVLVAARDYPLPDG
EEEECCCCHHHHHHHHCCCHHEEHEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCC
PLSIDTLSGFPWVLSQDGCGMRSALSRMLGAAGLPFDVAVEAFGSELQLSLVARGAGIGI
CEEEECCCCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHEEEEEECCCCCCE
AAPNALARSAHRDALRVVETVGLETRINVWIVHGALPGRLVRPVALLRDALGEVLDGENR
ECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
VGSDAVKAI
CCCHHHHCC
>Mature Secondary Structure
MNTRDLQAFVAVVDSGSMVAAAAKLHLTQPGLTRRVQNLETLLGMPLLERQSKPLKPTAA
CCCHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
GRDVYALARNVLGAVDELMAAGAPDSEPSGELRIGVPPFLSELALEQPIDRLRDAFPRLT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEE
LRVTAGWSPALMQGVERGALDVAAVMVPASSTLPDTFASTLLGTQPTVLVAARDYPLPDG
EEEECCCCHHHHHHHHCCCHHEEHEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCC
PLSIDTLSGFPWVLSQDGCGMRSALSRMLGAAGLPFDVAVEAFGSELQLSLVARGAGIGI
CEEEECCCCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHEEEEEECCCCCCE
AAPNALARSAHRDALRVVETVGLETRINVWIVHGALPGRLVRPVALLRDALGEVLDGENR
ECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
VGSDAVKAI
CCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA