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The map label for this gene is gmhA [H]

Identifier: 78064869

GI number: 78064869

Start: 250936

End: 251520

Strand: Direct

Name: gmhA [H]

Synonym: Bcep18194_A3392

Alternate gene names: 78064869

Gene position: 250936-251520 (Clockwise)

Preceding gene: 78064868

Following gene: 78064870

Centisome position: 6.79

GC content: 70.94

Gene sequence:

>585_bases
ATGTCAGTCGAACGTATTCAGCAACATTTCCGCGACAGCGCCGCGCTTCACGCCGAAGCGGCCGACGCGCTGTCGCTGCC
GATCGCAGCCGCGGTCGACGCGATGTTCGCCGCGCTGGCGAACGGCAACAAGATCGTCGCCTGCGGTGACGGCCCGTCGG
CCGCCGCCGCGCACTACCTCGCCGTGTCGCTCGTCGGCGGCTTCGAGCGCGAGCGCCCGGGCCTGCCCGCGATCGCGCTG
GCCACCGATGCGTCGCAGGGCGGCCTCGCGGGCGCGGTGTCCGCCGAACAACTGTTCGCGCAACAGGTGCGCGTGCTCGG
CCAGACCGGCGACATCCTGCTGGTGCTCGATCCGGCCGGCGCGTCGCCGCGCGTGCTGGCGGCGATCGACGAAGCGCACG
AGCGCGAGATGACCGTCGTCGCGCTGACGGGCGGCGACGGCCATGCGGTCGCGGCTGCGCTGTCCGATACCGATATTCCG
ATCAGCGTGCCCGCCGTTCGCGCGGCGCGCATCCACGAAGTCCATCTGCTGACCATCCACTGCCTGTGCGACGGCATCGA
CGCGATGCTGCTGGGTGAGGATTGA

Upstream 100 bases:

>100_bases
GTTCGTGCCGGACCCCCGGAGAGGGTGCCGGAGTACGGTAAACTCGCCGCACCCACGATGTCGCGCGATGCGTGCCACGC
GCCCAGTTCACCAGGAATCG

Downstream 100 bases:

>100_bases
ACGAAGGAGAGCCGTCGATGAATCAAAGCCGCGTCAAACAGACGCTCGTCAGAACCACGCTGCTCGCTGCGCTGACGGCG
GGCCTCGCCGTGTCGCTGCA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSVERIQQHFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYLAVSLVGGFERERPGLPAIAL
ATDASQGGLAGAVSAEQLFAQQVRVLGQTGDILLVLDPAGASPRVLAAIDEAHEREMTVVALTGGDGHAVAAALSDTDIP
ISVPAVRAARIHEVHLLTIHCLCDGIDAMLLGED

Sequences:

>Translated_194_residues
MSVERIQQHFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYLAVSLVGGFERERPGLPAIAL
ATDASQGGLAGAVSAEQLFAQQVRVLGQTGDILLVLDPAGASPRVLAAIDEAHEREMTVVALTGGDGHAVAAALSDTDIP
ISVPAVRAARIHEVHLLTIHCLCDGIDAMLLGED
>Mature_193_residues
SVERIQQHFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYLAVSLVGGFERERPGLPAIALA
TDASQGGLAGAVSAEQLFAQQVRVLGQTGDILLVLDPAGASPRVLAAIDEAHEREMTVVALTGGDGHAVAAALSDTDIPI
SVPAVRAARIHEVHLLTIHCLCDGIDAMLLGED

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=189, Percent_Identity=44.4444444444444, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786416, Length=189, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 19722; Mature: 19590

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVERIQQHFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AVSLVGGFERERPGLPAIALATDASQGGLAGAVSAEQLFAQQVRVLGQTGDILLVLDPAG
HHHHHCCCCCCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEECCCC
ASPRVLAAIDEAHEREMTVVALTGGDGHAVAAALSDTDIPISVPAVRAARIHEVHLLTIH
CCCEEEEEEHHHCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCHHHHEEEEEEEEEEE
CLCDGIDAMLLGED
EECCCCCEEEECCC
>Mature Secondary Structure 
SVERIQQHFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYL
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AVSLVGGFERERPGLPAIALATDASQGGLAGAVSAEQLFAQQVRVLGQTGDILLVLDPAG
HHHHHCCCCCCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEECCCC
ASPRVLAAIDEAHEREMTVVALTGGDGHAVAAALSDTDIPISVPAVRAARIHEVHLLTIH
CCCEEEEEEHHHCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCHHHHEEEEEEEEEEE
CLCDGIDAMLLGED
EECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA