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The map label for this gene is ybdL [H]

Identifier: 78064776

GI number: 78064776

Start: 140492

End: 141646

Strand: Direct

Name: ybdL [H]

Synonym: Bcep18194_A3299

Alternate gene names: 78064776

Gene position: 140492-141646 (Clockwise)

Preceding gene: 78064775

Following gene: 78064777

Centisome position: 3.8

GC content: 67.36

Gene sequence:

>1155_bases
ATGCGAAGCGCGACCGCGCCCCGTTCGAAACTGCCCGACGTCGGGACGACGATCTTCACGGTGATCGGCCAACTGGCTGC
TCAGCACGATGCGTTGAACCTGTCGCAGGGTGCGCCGAATTTCGCGCCCGATCCGTCGCTCGTCGAAGGCGTCGCGCGCG
CGATGCGCGACGGGCACAACCAGTACGCGCCGATGGCCGGCGTCATGGCGCTGCGCGAGCGGCTCGCCGAAAAGACCGAG
GCGCTGTACGGGACGCACTACGACCCGGCCACCGAGATCACGGTGATCGCGAGCGCGAGCGAAGGGCTCTACGCGGCGAT
CAGCGCGCTCGTGCACCCGGGCGACGAGGTGATCTACTTCGAGCCGTCGTTCGACAGCTATGCGCCGATCGTGCGGCTGC
AGGGCGCGACGCCGGTGGCGATCAAGCTGTCGCCCGAGCATTTCCGCGTGAACTGGGACGAAGTCGCCGCGGCGATCAAC
CCGCGCACGCGGATGATCATCGTCAACACGCCGCACAACCCGACCGCGACCGTATTCTCGGCCGACGATCTCGAACGGCT
CGCGCAGCTCACGCGCGATACCGGCATCGTGATCCTGTCCGACGAGGTCTACGAGCACGTCGTGTTCGACGGCGCGCAGC
ACCAGAGCATGGCGCGCCATCGCGAGCTGGCCGAGCGCAGCGTGATCGTGTCGTCGTTCGGCAAGTCGTTCCACGTGACG
GGCTGGCGGGTCGGCCATTGCGTCGCGCCGGCCGAGCTGATGGACGAGATCCGCAAGGTGCACCAGTTCATGGTGTTCGC
GGCCGACACGCCGATGCAGGTCGCGTTCGCGGAGATCCTCGCGCGACCGGACAGCTATCTCGGCCTGTCGGCGTTCTACC
AGGCCAAGCGCGACCTGCTCGCGCGCGAGCTGGCCGATTCCCGTTTCGAGCTGCTGCCGAGCGAAGGCTCGTTCTTCATG
CTCGCGCGCTTTCGCCACTTCTCGGACGAAAGCGACAGCGATTTCGTGCTGCGCCTGATCCGCGACGCGCGCGTCGCGAC
GATTCCGCTGTCGGCGTTCTACACCGACGGCACCGACGCCGGCGTGATCCGGCTCAGTTTTTCGAAGGACGACGCGACGC
TGGTCGAAGGCGCGCGGCGGCTGCGTTCGCTGTAA

Upstream 100 bases:

>100_bases
TTTCGATTGTCCACCGATATTGGCTCGGGCTAAATCGTGCGGCAGATGCAGGCCGTGCGCGTCGCGCGCGGCCGCCCGAA
GGACATCAGAAGGAGGAGTC

Downstream 100 bases:

>100_bases
AGCCCGTACGTAAACCAGCGACGGGAGCGTCGCATCGACCAGACACAGGAGATCACGATGAAGCACACGGCCACCCTGAA
ACTCGCGTTCGCACTCGCGT

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPSLVEGVARAMRDGHNQYAPMAGVMALRERLAEKTE
ALYGTHYDPATEITVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAIN
PRTRMIIVNTPHNPTATVFSADDLERLAQLTRDTGIVILSDEVYEHVVFDGAQHQSMARHRELAERSVIVSSFGKSFHVT
GWRVGHCVAPAELMDEIRKVHQFMVFAADTPMQVAFAEILARPDSYLGLSAFYQAKRDLLARELADSRFELLPSEGSFFM
LARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDAGVIRLSFSKDDATLVEGARRLRSL

Sequences:

>Translated_384_residues
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPSLVEGVARAMRDGHNQYAPMAGVMALRERLAEKTE
ALYGTHYDPATEITVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAIN
PRTRMIIVNTPHNPTATVFSADDLERLAQLTRDTGIVILSDEVYEHVVFDGAQHQSMARHRELAERSVIVSSFGKSFHVT
GWRVGHCVAPAELMDEIRKVHQFMVFAADTPMQVAFAEILARPDSYLGLSAFYQAKRDLLARELADSRFELLPSEGSFFM
LARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDAGVIRLSFSKDDATLVEGARRLRSL
>Mature_384_residues
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPSLVEGVARAMRDGHNQYAPMAGVMALRERLAEKTE
ALYGTHYDPATEITVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAIN
PRTRMIIVNTPHNPTATVFSADDLERLAQLTRDTGIVILSDEVYEHVVFDGAQHQSMARHRELAERSVIVSSFGKSFHVT
GWRVGHCVAPAELMDEIRKVHQFMVFAADTPMQVAFAEILARPDSYLGLSAFYQAKRDLLARELADSRFELLPSEGSFFM
LARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDAGVIRLSFSKDDATLVEGARRLRSL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=34.1772151898734, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=34.1772151898734, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=30.3030303030303, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=30.7692307692308, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=30.2798982188295, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=25.1336898395722, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=51.1873350923483, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=23.7569060773481, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788627, Length=342, Percent_Identity=26.3157894736842, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788332, Length=262, Percent_Identity=24.8091603053435, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=422, Percent_Identity=32.7014218009479, Blast_Score=223, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI71994476, Length=422, Percent_Identity=32.7014218009479, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17567369, Length=422, Percent_Identity=29.8578199052133, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17567663, Length=347, Percent_Identity=25.9365994236311, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=29.4871794871795, Blast_Score=170, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=33.9285714285714, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=33.9285714285714, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=33.9285714285714, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=33.9285714285714, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=25.4010695187166, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42321; Mature: 42321

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPSLVEGVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGVMALRERLAEKTEALYGTHYDPATEITVIASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAINPRTRMIIVNTPHNPTATVFS
CCCCCCCCCEEEECCCCEEEEEECCCCEECCHHHHHHHCCCCEEEEEEECCCCCCEEEEE
ADDLERLAQLTRDTGIVILSDEVYEHVVFDGAQHQSMARHRELAERSVIVSSFGKSFHVT
HHHHHHHHHHHHCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GWRVGHCVAPAELMDEIRKVHQFMVFAADTPMQVAFAEILARPDSYLGLSAFYQAKRDLL
CEEECCCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARELADSRFELLPSEGSFFMLARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDA
HHHHHCCHHHCCCCCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCC
GVIRLSFSKDDATLVEGARRLRSL
EEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPSLVEGVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGVMALRERLAEKTEALYGTHYDPATEITVIASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAINPRTRMIIVNTPHNPTATVFS
CCCCCCCCCEEEECCCCEEEEEECCCCEECCHHHHHHHCCCCEEEEEEECCCCCCEEEEE
ADDLERLAQLTRDTGIVILSDEVYEHVVFDGAQHQSMARHRELAERSVIVSSFGKSFHVT
HHHHHHHHHHHHCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GWRVGHCVAPAELMDEIRKVHQFMVFAADTPMQVAFAEILARPDSYLGLSAFYQAKRDLL
CEEECCCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARELADSRFELLPSEGSFFMLARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDA
HHHHHCCHHHCCCCCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCC
GVIRLSFSKDDATLVEGARRLRSL
EEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]