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The map label for this gene is yegE [H]

Identifier: 78050026

GI number: 78050026

Start: 5154773

End: 5156569

Strand: Reverse

Name: yegE [H]

Synonym: XCV4470

Alternate gene names: 78050026

Gene position: 5156569-5154773 (Counterclockwise)

Preceding gene: 78050027

Following gene: 78050025

Centisome position: 99.58

GC content: 68.67

Gene sequence:

>1797_bases
ATGCGCAGTCCGCTAGACTGCGCGGATTGCCCGGCCGCGAGCGCTCCGTTGAACCAGTGCGATACCGTCGTGTCATCTGC
GTCTAGCGAGGTCCAGCGCCTGGCACGTCTGGCGCTGTTGCAGGTGGTCGACACCGCCGCCGAGCCGTTCTTCGACGCGC
TGGCCGCTGCCGCGCAGGCGATCGCCGGTACCCCCATCGCGCTGGTCTCGCTGGTGGACGAACATCGGCAGTGGTGGAAG
GCCAACATCGGCCTGCCGGGGGTTTCGGAAACCCCACGCGAACTGGCGTTCTGCGCCCACACCATCCAGGGCGATGCGGT
GATGGAAGTGCGCGACGCGCCGGCCGACCCACGCTTCCACGACAACGCCCTGGTCACCGATGCGCCCGGTATCCGTTATT
ACGCCGGCGCCCCCATCGTGCTGCCGGATGGCTTACGCATGGGCACGGTGTGCGTGATCGACCAGCGCCCGCGCGCGCTG
GAGCCGGCGCAGTTGCAGGCCTTGCAGCAACTGGCCAGGGTGGCCGCCGAAGGCCTGGAGCAACGCCGTGTGATGCTCGA
GCGCGAGGCGGCCAATGCCCAGCTGCAGCAGCGGCTGCGCGAGAGCGAAGCGTTTCTGGAGCGCACCGGCCGGGTGGCCG
GGGTCGGCGGGTGGGAGGTGGACGTGGCCAGCGGCACGCTGATCTGGTCGGACCAGACCTGCCGCCTGCACGATGTTCCG
CCCGGTTACCGGCCCAGCCTGACCGAGGCGATCGGCTTCTATCCGCTGGAGGCGCGCGCGGTCATCACCGAAGCGGTCGA
AGCCTGCGTGCGGGACGGCACGTCCTGGGATCTGGAGCTGCCGCTGACCAGCGCCACCGGGCGGCGGCTATGGGTGCACA
GCACCGGATCGGTGGAACACGTGGATGGGCGCATGCGCCTGATCGGTGCGGTCCAGGACGTGACCGACCGGCACCAGGCC
GTGGACGCGCTGGCCGCCAGCGAGCGCAAGTTCCGCAAGATGTTCCAGTACAGCCTGGGCCTGATCTGCACCCACGACAT
GCATGGCCGGCTGGTCAGCATCAACCCGGCCGCCGCACGCTCGCTCGGCCGCAGCGTCGAGCAGATGGAAGGCCGCTCGC
TGGTGGAATTCGTGCGCCCCGAGCGCCACGCCGCCTTGCGCGGGTACCTCTCGCGGATGGTGCTCGATGGCCAGGATTCG
GGAGTGATCGAACTGGTGGCCGGCGACGGCAGCCTGCGCCATTGGCAGTACCACAACGTGCTGGACGTGGAATCCGACGC
CACGGTGGTGCTGGCGCATGCCCAGGACATCACCAACCAGTACCGGCAGGAGAAGCAGCTGCTGGAATGGTCGTTCACCG
ACCCGCTGACCAACTGCTACAACCGCCGATTCCTGGACGAACTGGACAAGCGCGACCCCAGCGTGCGCTGGGGCTGCATC
GTGTTGGACCTGGACAAGTTCAAACTGGTCAACGACACCCATGGCCATCAACGCGGCGACGAGGTGTTGGTGCAGATGGC
ATGGTTCCTCAACCAGCCGCTGCGCACCCAGGACCGCCTGGTACGCCTGGGCGGCGACGAATTCCTGGTGTTGCTACACC
AGGCCACCCAGGCACAGCTGGATGCGTTGACGCGCGACTACATGGGGGCCATCGAGGACGCGCCGATCCGCTTCACCCTC
GGCACCGCCCTGCGCCAGGACGGCGAAGCGCTGGCGGCGGTGGTCGATCGCGCCGACCACTCGCTGTACTCGCTGCGCCG
CGCCCGCCGCGGCACCGGCACCAGCGACCAGCGCTGA

Upstream 100 bases:

>100_bases
ACCACGCCGAACACCGACGCGCACGCCCCCGACTGAGCGGCGCCACAACCGCCGCAACGCTGCCCTGTGCAGTGGCGCAC
GGAACGCCGCCTTGGCTGGT

Downstream 100 bases:

>100_bases
GCTTGCGCGCACCTGAAAGCTGCACCGGACCCAGGTGACCGGCTGCGGGAACGCGTGCCGATGAATACGCGATCGCCTAT
CATGTAAACGTTTACAACTA

Product: putative signal transduction protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRSPLDCADCPAASAPLNQCDTVVSSASSEVQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDEHRQWWK
ANIGLPGVSETPRELAFCAHTIQGDAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRAL
EPAQLQALQQLARVAAEGLEQRRVMLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVP
PGYRPSLTEAIGFYPLEARAVITEAVEACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRMRLIGAVQDVTDRHQA
VDALAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDS
GVIELVAGDGSLRHWQYHNVLDVESDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPSVRWGCI
VLDLDKFKLVNDTHGHQRGDEVLVQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQATQAQLDALTRDYMGAIEDAPIRFTL
GTALRQDGEALAAVVDRADHSLYSLRRARRGTGTSDQR

Sequences:

>Translated_598_residues
MRSPLDCADCPAASAPLNQCDTVVSSASSEVQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDEHRQWWK
ANIGLPGVSETPRELAFCAHTIQGDAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRAL
EPAQLQALQQLARVAAEGLEQRRVMLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVP
PGYRPSLTEAIGFYPLEARAVITEAVEACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRMRLIGAVQDVTDRHQA
VDALAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDS
GVIELVAGDGSLRHWQYHNVLDVESDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPSVRWGCI
VLDLDKFKLVNDTHGHQRGDEVLVQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQATQAQLDALTRDYMGAIEDAPIRFTL
GTALRQDGEALAAVVDRADHSLYSLRRARRGTGTSDQR
>Mature_598_residues
MRSPLDCADCPAASAPLNQCDTVVSSASSEVQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDEHRQWWK
ANIGLPGVSETPRELAFCAHTIQGDAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRAL
EPAQLQALQQLARVAAEGLEQRRVMLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVP
PGYRPSLTEAIGFYPLEARAVITEAVEACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRMRLIGAVQDVTDRHQA
VDALAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDS
GVIELVAGDGSLRHWQYHNVLDVESDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPSVRWGCI
VLDLDKFKLVNDTHGHQRGDEVLVQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQATQAQLDALTRDYMGAIEDAPIRFTL
GTALRQDGEALAAVVDRADHSLYSLRRARRGTGTSDQR

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=429, Percent_Identity=25.4079254079254, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=30.6878306878307, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693134, Length=154, Percent_Identity=30.5194805194805, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787262, Length=197, Percent_Identity=28.9340101522843, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787541, Length=269, Percent_Identity=25.6505576208178, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081974, Length=156, Percent_Identity=32.6923076923077, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082007, Length=104, Percent_Identity=37.5, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 66220; Mature: 66220

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPLDCADCPAASAPLNQCDTVVSSASSEVQRLARLALLQVVDTAAEPFFDALAAAAQA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGTPIALVSLVDEHRQWWKANIGLPGVSETPRELAFCAHTIQGDAVMEVRDAPADPRFH
HCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCC
DNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRALEPAQLQALQQLARVAAEGLE
CCEEEECCCCCEEECCCCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
QRRVMLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCEEEECCCCEEEECCC
PGYRPSLTEAIGFYPLEARAVITEAVEACVRDGTSWDLELPLTSATGRRLWVHSTGSVEH
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCEEE
VDGRMRLIGAVQDVTDRHQAVDALAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECHHHHH
SLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDSGVIELVAGDGSLRHWQYHNV
HHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCE
LDVESDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPSVRWGCI
EECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
VLDLDKFKLVNDTHGHQRGDEVLVQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQATQAQL
EEECCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHEEECCCEEEEEEHHHHHHHH
DALTRDYMGAIEDAPIRFTLGTALRQDGEALAAVVDRADHSLYSLRRARRGTGTSDQR
HHHHHHHHCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRSPLDCADCPAASAPLNQCDTVVSSASSEVQRLARLALLQVVDTAAEPFFDALAAAAQA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGTPIALVSLVDEHRQWWKANIGLPGVSETPRELAFCAHTIQGDAVMEVRDAPADPRFH
HCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCC
DNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRALEPAQLQALQQLARVAAEGLE
CCEEEECCCCCEEECCCCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
QRRVMLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCEEEECCCCEEEECCC
PGYRPSLTEAIGFYPLEARAVITEAVEACVRDGTSWDLELPLTSATGRRLWVHSTGSVEH
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCEEE
VDGRMRLIGAVQDVTDRHQAVDALAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECHHHHH
SLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDSGVIELVAGDGSLRHWQYHNV
HHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCE
LDVESDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPSVRWGCI
EECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
VLDLDKFKLVNDTHGHQRGDEVLVQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQATQAQL
EEECCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHEEECCCEEEEEEHHHHHHHH
DALTRDYMGAIEDAPIRFTLGTALRQDGEALAAVVDRADHSLYSLRRARRGTGTSDQR
HHHHHHHHCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]