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The map label for this gene is hcp1 [H]

Identifier: 78049797

GI number: 78049797

Start: 4870553

End: 4871056

Strand: Reverse

Name: hcp1 [H]

Synonym: XCV4241

Alternate gene names: 78049797

Gene position: 4871056-4870553 (Counterclockwise)

Preceding gene: 78049798

Following gene: 78049796

Centisome position: 94.06

GC content: 60.91

Gene sequence:

>504_bases
ATGGCGTTCGACATGCACATCAAGTTCGGCAGCGGCAAGGTCAAGATCGAAGGCGCGTCCAACCACAAGAAGCACAAGGG
CGAAATTCCGATCCTGGCCTGGTCGTGGGGCGCGAGCAATTCCGGCGACCTGCACACCGGTGGCGGCTCGGCCAGCGGTG
GCAAGGCGCATATCCAGGACATCTCCATCACAAAGTACGTGGATGGTTGCTCCAACGCATTGCTCGATGCGGTATGCACC
GGGGCACGTGTGGAAAACGCCTGGCTGTACGTCACCAACGCCACTGGCGAGCAGAGCGACTTTCTCACCCTGGAATTGAG
CGAAGGCGTGCTGATTACCTCGTTGTCGACCGGCGGTTCCGGCGGCGAAGACCGCCTGACCGAAAACGTGACGCTGCACT
TCGGCAAGTTCAAGTACGGCTTCCAGCCGCAGGACGACAAGGGTGCCGCCCAGGGTGGCGCGAAGGAATTCACCTACGAC
ATCCAGGGTGTGGCCAAGGCCTAA

Upstream 100 bases:

>100_bases
TCGGCCGCCAAGGCCTGATCCGACGCATTCGCGTCACGGGCACGACGCGAATGCGCGTCGCGCCACCTCGTGTTGTCACT
CTCATTGAAGGAGCAGTTCC

Downstream 100 bases:

>100_bases
CACGAACGCGGGCAACCACAACGCTTTCGCCACGCAGGAGCGTTTGGCGACGCGGTGCGGCACGCAACATGCGTGTACAT
CGCTCGCTCTGCGCCGCCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MAFDMHIKFGSGKVKIEGASNHKKHKGEIPILAWSWGASNSGDLHTGGGSASGGKAHIQDISITKYVDGCSNALLDAVCT
GARVENAWLYVTNATGEQSDFLTLELSEGVLITSLSTGGSGGEDRLTENVTLHFGKFKYGFQPQDDKGAAQGGAKEFTYD
IQGVAKA

Sequences:

>Translated_167_residues
MAFDMHIKFGSGKVKIEGASNHKKHKGEIPILAWSWGASNSGDLHTGGGSASGGKAHIQDISITKYVDGCSNALLDAVCT
GARVENAWLYVTNATGEQSDFLTLELSEGVLITSLSTGGSGGEDRLTENVTLHFGKFKYGFQPQDDKGAAQGGAKEFTYD
IQGVAKA
>Mature_166_residues
AFDMHIKFGSGKVKIEGASNHKKHKGEIPILAWSWGASNSGDLHTGGGSASGGKAHIQDISITKYVDGCSNALLDAVCTG
ARVENAWLYVTNATGEQSDFLTLELSEGVLITSLSTGGSGGEDRLTENVTLHFGKFKYGFQPQDDKGAAQGGAKEFTYDI
QGVAKA

Specific function: Required for assembly of the protein secretion apparatus HSI-I. Actively secreted during chronic infection of cystic fibrosis patients [H]

COG id: COG3157

COG function: function code S; Hemolysin-coregulated protein (uncharacterized)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hcp1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017728
- InterPro:   IPR008514 [H]

Pfam domain/function: PF05638 DUF796 [H]

EC number: NA

Molecular weight: Translated: 17555; Mature: 17423

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDMHIKFGSGKVKIEGASNHKKHKGEIPILAWSWGASNSGDLHTGGGSASGGKAHIQD
CEEEEEEEECCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEECCCCCCCCCEEEEEE
ISITKYVDGCSNALLDAVCTGARVENAWLYVTNATGEQSDFLTLELSEGVLITSLSTGGS
EEEEEECCCHHHHHHHHHHCCCEECCEEEEEECCCCCCCCEEEEEECCCEEEEEECCCCC
GGEDRLTENVTLHFGKFKYGFQPQDDKGAAQGGAKEFTYDIQGVAKA
CCCCCEECEEEEEEECEEECCCCCCCCCCCCCCCEEEEEEEEEEECC
>Mature Secondary Structure 
AFDMHIKFGSGKVKIEGASNHKKHKGEIPILAWSWGASNSGDLHTGGGSASGGKAHIQD
EEEEEEEECCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEECCCCCCCCCEEEEEE
ISITKYVDGCSNALLDAVCTGARVENAWLYVTNATGEQSDFLTLELSEGVLITSLSTGGS
EEEEEECCCHHHHHHHHHHCCCEECCEEEEEECCCCCCCCEEEEEECCCEEEEEECCCCC
GGEDRLTENVTLHFGKFKYGFQPQDDKGAAQGGAKEFTYDIQGVAKA
CCCCCEECEEEEEEECEEECCCCCCCCCCCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]