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The map label for this gene is ykhA [H]

Identifier: 78049712

GI number: 78049712

Start: 4755171

End: 4755572

Strand: Reverse

Name: ykhA [H]

Synonym: XCV4156

Alternate gene names: 78049712

Gene position: 4755572-4755171 (Counterclockwise)

Preceding gene: 78049713

Following gene: 78049707

Centisome position: 91.83

GC content: 66.42

Gene sequence:

>402_bases
ATGACCAGTTCCACGCCCGTTGCACCGACCGAAGCCCGCATGGCCGAGATCGTGTTTCCCAATCACACCAACCATCTGGG
CACGCTGTTCGGTGGGCAGGCGCTGGCGTGGATGGACAAGGCCGCGTTCCTGGCCGCCTCGCGCTATGCGCGCCGCACCG
TGGTGACGGCGCGTTCGGATCAGGTGGATTTCAAGCTGCCGATCCGCCAGGGCCAGATGGTGGAAACCATCGCCCGCGTG
GTGTTGGTGGGGCGTAGCTCGATCACGGTGGAAGTGGAACTGATCGCCGAAGACCTGCTCAGCGGCGCACGCGAGCTGTG
CACGCGCGGGCAGTTCGTGATGATTGCGCTCGATGCCGATGGCAAGCCGACGGCGGTGCCGCCGCTGCCGGCAGCCGGCT
AA

Upstream 100 bases:

>100_bases
GATCCGCAGCGGCCAGTGCGCTACCACCTGGACCTGAGCTTCCTGCCGCCGCTGCGCAGATGATCGGGCTGGCTATCCTT
CCTTCTTACGGCACTTCTTC

Downstream 100 bases:

>100_bases
GAGCAGCGAATAAGACGACTGCGCTGCCGCCATGTGAGCGCAGCCAGTGCTCGGTGCGGTATGTATCACGTGCACTGCGG
TTGCTGCGCTTCATCCACAC

Product: putative acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTSSTPVAPTEARMAEIVFPNHTNHLGTLFGGQALAWMDKAAFLAASRYARRTVVTARSDQVDFKLPIRQGQMVETIARV
VLVGRSSITVEVELIAEDLLSGARELCTRGQFVMIALDADGKPTAVPPLPAAG

Sequences:

>Translated_133_residues
MTSSTPVAPTEARMAEIVFPNHTNHLGTLFGGQALAWMDKAAFLAASRYARRTVVTARSDQVDFKLPIRQGQMVETIARV
VLVGRSSITVEVELIAEDLLSGARELCTRGQFVMIALDADGKPTAVPPLPAAG
>Mature_132_residues
TSSTPVAPTEARMAEIVFPNHTNHLGTLFGGQALAWMDKAAFLAASRYARRTVVTARSDQVDFKLPIRQGQMVETIARVV
LVGRSSITVEVELIAEDLLSGARELCTRGQFVMIALDADGKPTAVPPLPAAG

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI22165400, Length=93, Percent_Identity=41.9354838709677, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI22165355, Length=93, Percent_Identity=41.9354838709677, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI18640736, Length=101, Percent_Identity=32.6732673267327, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787506, Length=130, Percent_Identity=30, Blast_Score=63, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 14235; Mature: 14103

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSTPVAPTEARMAEIVFPNHTNHLGTLFGGQALAWMDKAAFLAASRYARRTVVTARSD
CCCCCCCCCCCCCEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCC
QVDFKLPIRQGQMVETIARVVLVGRSSITVEVELIAEDLLSGARELCTRGQFVMIALDAD
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GKPTAVPPLPAAG
CCCCCCCCCCCCC
>Mature Secondary Structure 
TSSTPVAPTEARMAEIVFPNHTNHLGTLFGGQALAWMDKAAFLAASRYARRTVVTARSD
CCCCCCCCCCCCEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCC
QVDFKLPIRQGQMVETIARVVLVGRSSITVEVELIAEDLLSGARELCTRGQFVMIALDAD
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GKPTAVPPLPAAG
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]