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The map label for this gene is mphP [H]

Identifier: 78049707

GI number: 78049707

Start: 4750590

End: 4751417

Strand: Reverse

Name: mphP [H]

Synonym: XCV4151

Alternate gene names: 78049707

Gene position: 4751417-4750590 (Counterclockwise)

Preceding gene: 78049712

Following gene: 78049705

Centisome position: 91.75

GC content: 66.06

Gene sequence:

>828_bases
TTGCAGCCCGTTATTATAGAAGCCCGTTGGGGCTTGCCCCGATCACAGACTGTCCCAAATACGTTCGTGCCCGTTCAATT
CCCCCTCAAGCTTGTCGACCGGCGCATGATTGCGCCCACCGTGGCCCACTGCCAGTTCGTCCGTGACGACGGCCAGCCGC
TGGATTTCCAGCCCGGCCAGTTCATCCAGATCCATTTCGACTATGCCGATGGCACGCCGACCAAGCGCAGCTATTCGCTG
GCGACCATCCACGATCATGCGCTGGGACCGGGCGAGGCAGTGGAGATTGCGGTGAGCTTCGTGCCCGGCGGCTCGGCCAC
GGCCTTGTTCGAAGGCCTGGAGATTGGCGACCAGTTGCAGGCAAGCGGCCCCTACGGGCGCTTTTGCCTGCAGCCGGGCG
ATCACAACCAGCGTTACGTGCTGATCGCCACCGGCACTGGCGTCACCCCGTACCGCTCGATGCTGCCGCTGCTGGCCGAG
GCAATCGCCACCCGCGGTGTGCAGGTGGTGTTGCTGCAGGGCGCACGCACCCCGACCGAGCTGCTGTACGGCGACGACTT
CCGCGCGTTTGCCGATGCGCACCCGCAGTTCCGCTACGTGCCGTGCTTCTCGCGCGAAGTGCCCGAGCAGCCGCATGCCG
ATGTGCGGCACGGCTACGTGCAGCAGCACCTGGCCGAGTTCGCGCCCGATGCCGCGCACGACATCGCCTACCTGTGCGGC
AACCCGGACATGGTGGACACCTGCCTGGACGCGCTCAAAGCCGCCGGCCTGCCGAGTGCGCAGATTCGCCGCGAGAAGTA
CGTCAGCTCCACGCCGCCCAAGGTCTGA

Upstream 100 bases:

>100_bases
TGTCGTAGGTCTTGCGCAGATCGCACACGCGCAGGGCGGGCGCACGGGGAGATGGGGAATTCAAGCCGGGTCCTTCGCGC
CAGGGTGACGGCGCAGCGAG

Downstream 100 bases:

>100_bases
GGTGGCATGCAGGCGGCGCGTCGATGCCGCCTGTGTCTGCAGGCGTGCTGTGGCCTGCAGCGTGTGACGCCAAGTTGCTG
CGGTTTTAGCCGGCAGCGTC

Product: putative phenol hydroxylase component

Products: NA

Alternate protein names: Phenol 2-monooxygenase P5 component [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MQPVIIEARWGLPRSQTVPNTFVPVQFPLKLVDRRMIAPTVAHCQFVRDDGQPLDFQPGQFIQIHFDYADGTPTKRSYSL
ATIHDHALGPGEAVEIAVSFVPGGSATALFEGLEIGDQLQASGPYGRFCLQPGDHNQRYVLIATGTGVTPYRSMLPLLAE
AIATRGVQVVLLQGARTPTELLYGDDFRAFADAHPQFRYVPCFSREVPEQPHADVRHGYVQQHLAEFAPDAAHDIAYLCG
NPDMVDTCLDALKAAGLPSAQIRREKYVSSTPPKV

Sequences:

>Translated_275_residues
MQPVIIEARWGLPRSQTVPNTFVPVQFPLKLVDRRMIAPTVAHCQFVRDDGQPLDFQPGQFIQIHFDYADGTPTKRSYSL
ATIHDHALGPGEAVEIAVSFVPGGSATALFEGLEIGDQLQASGPYGRFCLQPGDHNQRYVLIATGTGVTPYRSMLPLLAE
AIATRGVQVVLLQGARTPTELLYGDDFRAFADAHPQFRYVPCFSREVPEQPHADVRHGYVQQHLAEFAPDAAHDIAYLCG
NPDMVDTCLDALKAAGLPSAQIRREKYVSSTPPKV
>Mature_275_residues
MQPVIIEARWGLPRSQTVPNTFVPVQFPLKLVDRRMIAPTVAHCQFVRDDGQPLDFQPGQFIQIHFDYADGTPTKRSYSL
ATIHDHALGPGEAVEIAVSFVPGGSATALFEGLEIGDQLQASGPYGRFCLQPGDHNQRYVLIATGTGVTPYRSMLPLLAE
AIATRGVQVVLLQGARTPTELLYGDDFRAFADAHPQFRYVPCFSREVPEQPHADVRHGYVQQHLAEFAPDAAHDIAYLCG
NPDMVDTCLDALKAAGLPSAQIRREKYVSSTPPKV

Specific function: Probable electron transfer from NADPH, via FAD and the 2Fe-2S center, to the oxygenase activity site of the enzyme [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=229, Percent_Identity=31.0043668122271, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: =1.14.13.7 [H]

Molecular weight: Translated: 30177; Mature: 30177

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVIIEARWGLPRSQTVPNTFVPVQFPLKLVDRRMIAPTVAHCQFVRDDGQPLDFQPGQ
CCCEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCC
FIQIHFDYADGTPTKRSYSLATIHDHALGPGEAVEIAVSFVPGGSATALFEGLEIGDQLQ
EEEEEEEECCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHCCCCCCHHC
ASGPYGRFCLQPGDHNQRYVLIATGTGVTPYRSMLPLLAEAIATRGVQVVLLQGARTPTE
CCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHH
LLYGDDFRAFADAHPQFRYVPCFSREVPEQPHADVRHGYVQQHLAEFAPDAAHDIAYLCG
HEECCCHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCEEEECC
NPDMVDTCLDALKAAGLPSAQIRREKYVSSTPPKV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQPVIIEARWGLPRSQTVPNTFVPVQFPLKLVDRRMIAPTVAHCQFVRDDGQPLDFQPGQ
CCCEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCC
FIQIHFDYADGTPTKRSYSLATIHDHALGPGEAVEIAVSFVPGGSATALFEGLEIGDQLQ
EEEEEEEECCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHCCCCCCHHC
ASGPYGRFCLQPGDHNQRYVLIATGTGVTPYRSMLPLLAEAIATRGVQVVLLQGARTPTE
CCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHH
LLYGDDFRAFADAHPQFRYVPCFSREVPEQPHADVRHGYVQQHLAEFAPDAAHDIAYLCG
HEECCCHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCEEEECC
NPDMVDTCLDALKAAGLPSAQIRREKYVSSTPPKV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12732969 [H]