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The map label for this gene is yafC [H]

Identifier: 78049436

GI number: 78049436

Start: 4467483

End: 4468544

Strand: Reverse

Name: yafC [H]

Synonym: XCV3880

Alternate gene names: 78049436

Gene position: 4468544-4467483 (Counterclockwise)

Preceding gene: 78049440

Following gene: 78049434

Centisome position: 86.29

GC content: 64.69

Gene sequence:

>1062_bases
GTGTGGCCATGTGGCTCTCCATCGAAGTGCATCAGAACGAAGGCACACGTTAGGCGGGTCTGCAGTTGCGATAAATCGGC
AGCATCGACCAACACTGTTTGTAGAATCCAAACAATCTTGGCCGCGGGAGCAGTGGTGGATCGATTCGATGCAATGCAGG
CGTTTGCGCGCGTGGTCGAGACCGGCAGTTTCACCAAGGCGGCCGAACACCTGGACATGAGCCGCGCCAGCGTGACCCAG
CTGGTGCAGCAACTGGAAGCGCGCCTGCGGGTTAAGCTGCTCAATCGCACCACGCGCCGGGTGCAGGTCACTGCCGATGG
CGCGGCCTATTACGAGCGCGTGCTGCGCCTGCTGGCAGACCTGGACGATGCCGAAACCAGCCTGTCGGTTGCAGCCAGCT
TGCCACGCGGGCGCCTGCGCGTGGACGTGCCCAGCCCGTTGGCGCGGCTGATCCTGATGCCGGCGTTGCCGGCATTCCAT
GCGCGTTATCCGGAGATCCAGCTGGACATGGGCGTGAGCGACCGCCGGGTGGATCTGATCGGCGAAAACGTCGATTGCGT
GATACGCGGCGGCACCATCACCGACCAGTCGCTGATCGCGCGTCACGTGGGCGACCTGCAGGCCGGCGTGTACGCAGCGC
CCGATTACCTGCAGCGGCTGGGTACCCCGACGCATCCAACCGAGCTGGAAAATACACGGCATCGTTGCGTTGGCTTCATG
CGCTGGGGCAGCAGCACAACCGTGCCGTATGTGATGCAACGCGGCGACGAGGCGGTGCGCGTGCATGGTCGCCACGTGGT
GGCCGCCGACGATGGCAATGCCTATCTGGCCGCCGGCCTGGCCGGCATGGGTGTGCTGTGGCTGCCGGTGTACATGGCCA
ACGCGCATGTCGCCAGCGGCGAACTGGTGCCGATCTTTCAGGACTGGCAGCTGGAAGCGATGCCGCTGTCGATCGCCTTC
CCACCCAACCGCCATGTCAGCGCCAAGCTGCGCGTGTTCATCGATTGGGTGATTGCGCTGATGGCCGAGCATGCGCCAGT
GATGGCGCCCGCACCGCGGTGA

Upstream 100 bases:

>100_bases
ACCTGGCCGGCGACAAACAGCAGGTCATCGGCGCGTACCGCCGGCGAGTAATGGTGGCGCTCGTACAGGGCGTGGCGCCC
CTGCGGGAAAACGACGTCGC

Downstream 100 bases:

>100_bases
GCGCCACAGGGATGCGCGGCGCTATTGCTCACTTCGCGCCGCACCGGGTACCGCCAGCCGCTGATCGCTGCATAGGGCGA
ACGTGCATAGACCCACTGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MWPCGSPSKCIRTKAHVRRVCSCDKSAASTNTVCRIQTILAAGAVVDRFDAMQAFARVVETGSFTKAAEHLDMSRASVTQ
LVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLADLDDAETSLSVAASLPRGRLRVDVPSPLARLILMPALPAFH
ARYPEIQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGDLQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFM
RWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGVLWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAF
PPNRHVSAKLRVFIDWVIALMAEHAPVMAPAPR

Sequences:

>Translated_353_residues
MWPCGSPSKCIRTKAHVRRVCSCDKSAASTNTVCRIQTILAAGAVVDRFDAMQAFARVVETGSFTKAAEHLDMSRASVTQ
LVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLADLDDAETSLSVAASLPRGRLRVDVPSPLARLILMPALPAFH
ARYPEIQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGDLQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFM
RWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGVLWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAF
PPNRHVSAKLRVFIDWVIALMAEHAPVMAPAPR
>Mature_353_residues
MWPCGSPSKCIRTKAHVRRVCSCDKSAASTNTVCRIQTILAAGAVVDRFDAMQAFARVVETGSFTKAAEHLDMSRASVTQ
LVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLADLDDAETSLSVAASLPRGRLRVDVPSPLARLILMPALPAFH
ARYPEIQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGDLQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFM
RWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGVLWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAF
PPNRHVSAKLRVFIDWVIALMAEHAPVMAPAPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=35.6902356902357, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=32.7868852459016, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=30.5263157894737, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=28.4210526315789, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789639, Length=309, Percent_Identity=28.8025889967638, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=29.7029702970297, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=27.7777777777778, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=143, Percent_Identity=29.3706293706294, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788706, Length=298, Percent_Identity=24.8322147651007, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38692; Mature: 38692

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWPCGSPSKCIRTKAHVRRVCSCDKSAASTNTVCRIQTILAAGAVVDRFDAMQAFARVVE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGSFTKAAEHLDMSRASVTQLVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHC
LDDAETSLSVAASLPRGRLRVDVPSPLARLILMPALPAFHARYPEIQLDMGVSDRRVDLI
CCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCHHHHCCCCCEEEECCCCCCEEEEE
GENVDCVIRGGTITDQSLIARHVGDLQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFM
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCEECHHHHHHCCCCCCCCHHHCCHHHHEEEE
RWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGVLWLPVYMANAHVASG
ECCCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCEECCC
ELVPIFQDWQLEAMPLSIAFPPNRHVSAKLRVFIDWVIALMAEHAPVMAPAPR
CEEEEEECCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MWPCGSPSKCIRTKAHVRRVCSCDKSAASTNTVCRIQTILAAGAVVDRFDAMQAFARVVE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGSFTKAAEHLDMSRASVTQLVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHC
LDDAETSLSVAASLPRGRLRVDVPSPLARLILMPALPAFHARYPEIQLDMGVSDRRVDLI
CCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCHHHHCCCCCEEEECCCCCCEEEEE
GENVDCVIRGGTITDQSLIARHVGDLQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFM
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCEECHHHHHHCCCCCCCCHHHCCHHHHEEEE
RWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGVLWLPVYMANAHVASG
ECCCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCEECCC
ELVPIFQDWQLEAMPLSIAFPPNRHVSAKLRVFIDWVIALMAEHAPVMAPAPR
CEEEEEECCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]