Click here to switch to the map view.

The map label for this gene is dadA2 [H]

Identifier: 78049365

GI number: 78049365

Start: 4394347

End: 4395636

Strand: Reverse

Name: dadA2 [H]

Synonym: XCV3809

Alternate gene names: 78049365

Gene position: 4395636-4394347 (Counterclockwise)

Preceding gene: 78049367

Following gene: 78049364

Centisome position: 84.88

GC content: 69.61

Gene sequence:

>1290_bases
ATGCGTGTGCTCATTCTCGGCAGCGGCGTCATCGGCGTGACCAGTGCGTGGTACCTGGCGCAGGCCGGTTGCGAAGTGAC
CGTGGTCGACCGCCAGCCGGCAGCGGCGCTGGAGACCAGCTACGCCAACGCCGGCCAGCTGTCGTTCGGCTACACCTCGC
CGTGGGCGGCGCCCGGCGTGCCCGGCAAAGCGGTGAAATGGCTGTTCGAGCAGCACGCACCGCTGTCGATCCGCCCCACC
CGCGACCTGCGCCAGCTGGCCTGGCTGAGCCAGATGCTGCGCAACTGCACCGCCGAACGCTATGCGGTGAACAAGGCGCG
CATGGTGCGCATGTCCGACTACAGCCGCGATTGCCTCAACGCCTTGCGCGCCGAGACCGGCATCGAATTCGAAGGCCGCC
AGCTTGGCACCACGCAGTTGTTCCGCACCCAGCAGCAGCTGGATGCGGCCGCGCAGGACATCGAGGTGCTGGCCCAGTAC
GGCGTACCGTACGAGCTGCTGAGCCCGGCGCAGATCGCGCAGTTCGAACCCGGCCTGGCCGGCGGCGGCGCGCAGATGGC
CGGCGCGCTGCGCCTGCCCGAAGACCAGACCGGCGACTGCCGGCTGTTTACCCAGCGCCTGGCCGAACTGGCCGCGCAGG
CAGGCGTCACGTTCCGCTACGGGCAGCAGATCGAGCGGCTGGAGCACGCTGGCGGCCAGGTCAGCGGCGTGCAGATCGAT
GGCCGCATGGAAACTGCCGACCGCTACGTGCTGGCGCTGGGCAGCTATTCGGCCGATTTGCTGCTCTCGCTCGGCCTGCA
CCTGCCGGTGTACCCGCTCAAGGGCTATTCGCTCACCATCCCGATCGTCGATGCGCAGCGCGCGCCGACCTCCACCGTAC
TGGACGAGAGCTACAAGATCGCGCTCACCCGTTTCGACGACCGCATCCGCGTCGGCGGCATGGCCGAGGTGGCCGGCTTC
GATCTGTCGTTGAATCCGCGTCGTCGCGCCACCCTGGAAATGGTCGTCAACGACCTGTTCCCCGGCGGCGGCGATCTGGC
CCAGGCCGAGTTCTGGACCGGCCTGCGCCCGGCCACCCCGGACGGCACCCCGGTGGTGGGCGCCACGCCCTATGCCAACC
TGTTCCTCAACACCGGGCATGGCACGCTGGGCTGGACCATGGCCTGCGGTTCGGGGCGCTACCTGGCCGACCTCATGCAG
GGCCGCACGCCGGAGATCGATACCGAAGGTCTGGACGTGTTCCGCTACCTGTCGCCGCGCAGCGCGCGCGCGCAGCGGGA
GGCCGCGTAG

Upstream 100 bases:

>100_bases
GCCGATTCCAGAAATGGCACTGCCTGGCTCGCAATATACTGCGTCTAACTGTCCCCCTCGGCGTGTGGTTGTGGGGGAAT
GCCCTTTTCAGGAGAACGAC

Downstream 100 bases:

>100_bases
TGCGTCCTGCGCAAGCGTCGATCGATCTGGAGGCGTTGCGCCACAACTACCGCCTGGCCAGGCGCCTGGGCGGCAGCAAG
GCGCTGGCGGTGGTCAAGGC

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGQQIERLEHAGGQVSGVQID
GRMETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DLSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTEGLDVFRYLSPRSARAQREAA

Sequences:

>Translated_429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGQQIERLEHAGGQVSGVQID
GRMETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DLSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTEGLDVFRYLSPRSARAQREAA
>Mature_429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGQQIERLEHAGGQVSGVQID
GRMETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DLSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTEGLDVFRYLSPRSARAQREAA

Specific function: Oxidative deamination of D-amino acids [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI194306651, Length=339, Percent_Identity=24.4837758112094, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787438, Length=416, Percent_Identity=62.0192307692308, Blast_Score=528, Evalue=1e-151,
Organism=Drosophila melanogaster, GI28571104, Length=332, Percent_Identity=23.1927710843373, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 46568; Mature: 46568

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCEECCCCCCCCCCCC
PGKAVKWLFEQHAPLSIRPTRDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLN
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHHEEEECCCCHHHHH
ALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQYGVPYELLSPAQIAQFEPGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCC
GGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGQQIERLEHAGGQVSGVQID
CCCHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEEEC
GRMETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKI
CCCCCCCEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHCCCEEE
ALTRFDDRIRVGGMAEVAGFDLSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATP
EEEECCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQGRTPEIDTEGLDVFRYLSPR
CCCEEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCC
SARAQREAA
HHHHHHCCC
>Mature Secondary Structure
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCEECCCCCCCCCCCC
PGKAVKWLFEQHAPLSIRPTRDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLN
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHHEEEECCCCHHHHH
ALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQYGVPYELLSPAQIAQFEPGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCC
GGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGQQIERLEHAGGQVSGVQID
CCCHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEEEC
GRMETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKI
CCCCCCCEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHCCCEEE
ALTRFDDRIRVGGMAEVAGFDLSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATP
EEEECCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQGRTPEIDTEGLDVFRYLSPR
CCCEEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCC
SARAQREAA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]