Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 78049364

GI number: 78049364

Start: 4393250

End: 4394347

Strand: Reverse

Name: alr [H]

Synonym: XCV3808

Alternate gene names: 78049364

Gene position: 4394347-4393250 (Counterclockwise)

Preceding gene: 78049365

Following gene: 78049362

Centisome position: 84.86

GC content: 68.76

Gene sequence:

>1098_bases
GTGCGTCCTGCGCAAGCGTCGATCGATCTGGAGGCGTTGCGCCACAACTACCGCCTGGCCAGGCGCCTGGGCGGCAGCAA
GGCGCTGGCGGTGGTCAAGGCCGACGCGTACGGGCATGGTGCAGTGCGCTGCGCGCAGGCGCTGGAGCCGGAAGCCGATG
GCTTTGCAGTGGCCTGCATCGAAGAGGCGCTGGAACTGCGCCAGGCCGGCATCCGTGCGCCGATCCTGTTGCTGGAGGGA
TTTTTCGAACACGACGAGTTGCGCCTGATCGCCGAGCACGATCTGTGGACGGTGGCGGCCACGCAGCAGCAGGTGCGCGC
GCTGGCCGAGTTCCAGAGCCCGCGGCCGTTGCGGGTGTGGTTGAAGATGGACAGCGGCATGCATCGGCTGGGCCTGTCGC
CGGAGGATTTCCGCGCCGCCTGGTTGCGCCTGCGCGGGCTACCGCAGATCGCCTCGCTGGTGCTGATGACCCACCTGGCA
CGTGCCGACGAGCTGGACTGCAGCCGCACCGACGAGCAGGCGGTGGCCTTTGCGCTCACCGCCGGCGGCATGCGCGCAGA
AACCAGCCTGCGCAATTCGCCCGGCCTTCTTGGCTGGCCGGCGCTGCGCAACGATTGGTCGCGCCCCGGGCTGATGTTGT
ACGGCGCCAACCCGTTCCCGCAGCACACCGAAAACACCGCGCAACTGCGTCCGGTGATGACGCTGCGCTCGCGCATCATT
TCGGTGCGCGAGTTGCCGGCCGGCGAGCCGGTGGGCTACGGCGCCCGCTTCGTTGCCGAACGACCCACGCGTGTCGGCGT
GGTGGCGATGGGCTATGCCGACGGCTATCCGCAGTTCGCGCCCAACGGCACCCCGGTGCTGGTGGACGGGCAGATCTGCC
CGTTGATCGGTCGCGTCTCGATGGACATGCTCACCGTGGACCTCACCGACCACCCGCAGGCCGACATCGGCACGCCGGTG
CAGCTGTGGGGCGACGCACCGCAGGTCAGCGCGCTGGCAGCGCAATGCAACGTCAGCGCCTACCAGCTGCTGTGCGGGCT
CAAGCGGGTACCGCGGATCTATGTGGGGGAGGCGGCAGTAGGCAAACTTTCAGCATAG

Upstream 100 bases:

>100_bases
ACCTCATGCAGGGCCGCACGCCGGAGATCGATACCGAAGGTCTGGACGTGTTCCGCTACCTGTCGCCGCGCAGCGCGCGC
GCGCAGCGGGAGGCCGCGTA

Downstream 100 bases:

>100_bases
GTGCATCCCTTCTCCCCCAGGGAGAAGGTGGCGCGTAGCGCCGGATGAGGGTGCGAGCGAAGCTGCGTGCAGTTTGAATG
CCACGCGTGCTGCGCGCGGT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MRPAQASIDLEALRHNYRLARRLGGSKALAVVKADAYGHGAVRCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEG
FFEHDELRLIAEHDLWTVAATQQQVRALAEFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLA
RADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQHTENTAQLRPVMTLRSRII
SVRELPAGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQICPLIGRVSMDMLTVDLTDHPQADIGTPV
QLWGDAPQVSALAAQCNVSAYQLLCGLKRVPRIYVGEAAVGKLSA

Sequences:

>Translated_365_residues
MRPAQASIDLEALRHNYRLARRLGGSKALAVVKADAYGHGAVRCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEG
FFEHDELRLIAEHDLWTVAATQQQVRALAEFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLA
RADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQHTENTAQLRPVMTLRSRII
SVRELPAGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQICPLIGRVSMDMLTVDLTDHPQADIGTPV
QLWGDAPQVSALAAQCNVSAYQLLCGLKRVPRIYVGEAAVGKLSA
>Mature_365_residues
MRPAQASIDLEALRHNYRLARRLGGSKALAVVKADAYGHGAVRCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEG
FFEHDELRLIAEHDLWTVAATQQQVRALAEFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLA
RADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQHTENTAQLRPVMTLRSRII
SVRELPAGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQICPLIGRVSMDMLTVDLTDHPQADIGTPV
QLWGDAPQVSALAAQCNVSAYQLLCGLKRVPRIYVGEAAVGKLSA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=359, Percent_Identity=46.7966573816156, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1787439, Length=358, Percent_Identity=45.5307262569832, Blast_Score=289, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39737; Mature: 39737

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAQASIDLEALRHNYRLARRLGGSKALAVVKADAYGHGAVRCAQALEPEADGFAVACI
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEHHHH
EEALELRQAGIRAPILLLEGFFEHDELRLIAEHDLWTVAATQQQVRALAEFQSPRPLRVW
HHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHHHHHHCCCCCEEEE
LKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLARADELDCSRTDEQAVAFALT
EEECCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEEE
AGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQHTENTAQLRPVMTLRSRII
CCCCCCCCCCCCCCCCEECHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
SVRELPAGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQICPLIGRVS
HHHCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHCE
MDMLTVDLTDHPQADIGTPVQLWGDAPQVSALAAQCNVSAYQLLCGLKRVPRIYVGEAAV
EEEEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCC
GKLSA
CCCCC
>Mature Secondary Structure
MRPAQASIDLEALRHNYRLARRLGGSKALAVVKADAYGHGAVRCAQALEPEADGFAVACI
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEHHHH
EEALELRQAGIRAPILLLEGFFEHDELRLIAEHDLWTVAATQQQVRALAEFQSPRPLRVW
HHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHHHHHHCCCCCEEEE
LKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLARADELDCSRTDEQAVAFALT
EEECCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEEE
AGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQHTENTAQLRPVMTLRSRII
CCCCCCCCCCCCCCCCEECHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
SVRELPAGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQICPLIGRVS
HHHCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHCE
MDMLTVDLTDHPQADIGTPVQLWGDAPQVSALAAQCNVSAYQLLCGLKRVPRIYVGEAAV
EEEEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCC
GKLSA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]