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The map label for this gene is yhcW [H]

Identifier: 78049354

GI number: 78049354

Start: 4383415

End: 4384095

Strand: Reverse

Name: yhcW [H]

Synonym: XCV3798

Alternate gene names: 78049354

Gene position: 4384095-4383415 (Counterclockwise)

Preceding gene: 78049355

Following gene: 78049346

Centisome position: 84.66

GC content: 68.87

Gene sequence:

>681_bases
ATGACCCACAGTGCAGCGCTGCCGTTTCGCCCGCAGGCGGTGATCTTCGACATGGATGGCTTGATGCTCGATAGCGAGCG
CGCCATCACGGCCTGTCTGGCGCAGGCCGCCGACGACCAGGGTCTGCAGATCGAACCGGCCTTCTGGTTGCGCATGGTGG
GCACCGGCGATGCGGCCTGCCGCCGGCTGCTCGGCGAACGGATCGGCGAGGCCGCGGCCGACACCATGCTGGCGCATGCG
CAACGGCTGTATGCCGCTGCGGTCGAGCGCGGCATCCCGCATCGGCCCGGCATCGTTGCGCTGTTGGACTATCTGGCAGC
CCAGCGCATGCCGCGCGCGGTGGCCACCTCCACCCAGCGCCCGCTGGCGCTGCGCAAGCTGGAAGCGGCCGATCTGTTGT
GGCGCTTCGATGCCGTGTGCACGGCCAGCGACGTGGTCCATCCGAAACCTGCGCCGGATATCTACCTGCTGGCTGCGCGC
ACCTTGGCGGTAGACCCTGCGCACTGCCTGGTGCTGGAAGACTCGCCCACCGGCGTGCGTGCAGCATTGGCGGCCGGCAT
GACACCGATCCAGATTCCGGACCTGCTCGAGCCCGACGCCACCGTGCGCGCGCTCGGCCACCGCATCCTGCCCTCGCTGA
GTGATGCACAACGCTTGCTGGAAGCACGCTTGTCGGGGTGA

Upstream 100 bases:

>100_bases
GCCGCATCGGCGGCCTGTCGCTGGATGGATTGTCGTCGGGGCAATGGCGTGCGCTGGAAGCGAACGATCTTGAGGTGTTG
TTCAGCCGCGGCGCTCCGGC

Downstream 100 bases:

>100_bases
CGGGTTCGAGTGGATACGTCGCGGGGCCAGTTCATGCGCCAGCCCGGCTGATCATGCAGGTGCTGCCGACCGCCTCGCTG
CGCTGCTCTTAGAGCGTGTT

Product: HAD family phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTHSAALPFRPQAVIFDMDGLMLDSERAITACLAQAADDQGLQIEPAFWLRMVGTGDAACRRLLGERIGEAAADTMLAHA
QRLYAAAVERGIPHRPGIVALLDYLAAQRMPRAVATSTQRPLALRKLEAADLLWRFDAVCTASDVVHPKPAPDIYLLAAR
TLAVDPAHCLVLEDSPTGVRAALAAGMTPIQIPDLLEPDATVRALGHRILPSLSDAQRLLEARLSG

Sequences:

>Translated_226_residues
MTHSAALPFRPQAVIFDMDGLMLDSERAITACLAQAADDQGLQIEPAFWLRMVGTGDAACRRLLGERIGEAAADTMLAHA
QRLYAAAVERGIPHRPGIVALLDYLAAQRMPRAVATSTQRPLALRKLEAADLLWRFDAVCTASDVVHPKPAPDIYLLAAR
TLAVDPAHCLVLEDSPTGVRAALAAGMTPIQIPDLLEPDATVRALGHRILPSLSDAQRLLEARLSG
>Mature_225_residues
THSAALPFRPQAVIFDMDGLMLDSERAITACLAQAADDQGLQIEPAFWLRMVGTGDAACRRLLGERIGEAAADTMLAHAQ
RLYAAAVERGIPHRPGIVALLDYLAAQRMPRAVATSTQRPLALRKLEAADLLWRFDAVCTASDVVHPKPAPDIYLLAART
LAVDPAHCLVLEDSPTGVRAALAAGMTPIQIPDLLEPDATVRALGHRILPSLSDAQRLLEARLSG

Specific function: Unknown

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=216, Percent_Identity=30.0925925925926, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI207113149, Length=240, Percent_Identity=30.8333333333333, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1789046, Length=185, Percent_Identity=31.8918918918919, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082080, Length=204, Percent_Identity=31.3725490196078, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787576, Length=193, Percent_Identity=31.6062176165803, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788021, Length=198, Percent_Identity=31.3131313131313, Blast_Score=61, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17137324, Length=211, Percent_Identity=33.6492890995261, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI116008157, Length=219, Percent_Identity=34.703196347032, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550911, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24249; Mature: 24118

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSAALPFRPQAVIFDMDGLMLDSERAITACLAQAADDQGLQIEPAFWLRMVGTGDAAC
CCCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHCCCCCCEECHHHEEEEECCCHHHH
RRLLGERIGEAAADTMLAHAQRLYAAAVERGIPHRPGIVALLDYLAAQRMPRAVATSTQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHCCCC
PLALRKLEAADLLWRFDAVCTASDVVHPKPAPDIYLLAARTLAVDPAHCLVLEDSPTGVR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHEECCCEEEEECCCCCCHH
AALAAGMTPIQIPDLLEPDATVRALGHRILPSLSDAQRLLEARLSG
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
THSAALPFRPQAVIFDMDGLMLDSERAITACLAQAADDQGLQIEPAFWLRMVGTGDAAC
CCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHCCCCCCEECHHHEEEEECCCHHHH
RRLLGERIGEAAADTMLAHAQRLYAAAVERGIPHRPGIVALLDYLAAQRMPRAVATSTQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHCCCC
PLALRKLEAADLLWRFDAVCTASDVVHPKPAPDIYLLAARTLAVDPAHCLVLEDSPTGVR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHEECCCEEEEECCCCCCHH
AALAAGMTPIQIPDLLEPDATVRALGHRILPSLSDAQRLLEARLSG
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]