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The map label for this gene is dinP [H]

Identifier: 78049296

GI number: 78049296

Start: 4320384

End: 4321463

Strand: Reverse

Name: dinP [H]

Synonym: XCV3740

Alternate gene names: 78049296

Gene position: 4321463-4320384 (Counterclockwise)

Preceding gene: 78049299

Following gene: 78049295

Centisome position: 83.45

GC content: 64.91

Gene sequence:

>1080_bases
ATGCGCAAGATCGTGCACGTGGACATGGATGCGTTCTACGCGTCCGTGGAGCAGCGTGACGATCCGGGCCTGCGCGGCAA
GCCGGTAGTGGTGGCCTGGCGCGGCGCGCGCTCGGTGGTGTGCGCGGCCTCCTACGAAGCGCGGACCTTCGGTATTCGCT
CGGCGATGCCGGCCGTGCGTGCCGAGCGCCTGTGCCCGGACGCGATCTTCGTGCCGCCGGATTTTGCGCGCTACAAGGCG
GTGTCGCGGCAAGTACGCGAGATTTTCCATCGTCATACCGACTTGGTGGAGCCGTTGTCGCTGGACGAGGCCTATCTGGA
CGTCACGCACGCCAAAACCGGCATGCAGTTGGCCACCGAGGTCGCGCAGTTGATCCGTACGCAGATCCGCGAGGAAACCC
AGCTCACCGCATCGGCCGGCATCGCGCCGAACAAGTTCCTGGCCAAGATTGCGTCGGATTGGCGCAAACCCGATGGCCAG
TTCGTGATTGCGCCCAGCCGCGTGGATGCATTTTTGCTGCCGCTCAAGGTCAATCGCATTCCCGGCGTAGGCAAGGTGAT
GGATGGCAAGTTGGCGGCGCTGGGCATCGTCACTGTGGCCGATCTGCGCCAGCGGCCATTGGAGGAACTGCAGGCGCATT
TCGGCAGTTTCGGTCAGAGCCTGTATCGCCGCGCGCGCGGCATCGACGAGCGCCCGGTCGAGCCGGATCAGGAAGTGCAA
TCGGTCTCCTCGGAAGACACCTTCAGCGAAGATCTGGCGCTTGATGCACTGGACCCGCACATCCTGCGGCTGGCCGAAAA
GACCTGGCTCGCCACGCGCCGCACCGAACGCATCGGGCGCACGGTCGTGCTGAAATTGAAGACCTCGAATTTTCGCATCC
TGACGCGCTCCTACACGCCCGAGCAGCCGCCTACCTCGCAGGAGGCGCTGGCGCAGATTGCCCTGGCATTGACCCGCCGC
GTGGAGCTGCCCACGCAGACGCGCTATCGCCTGGTCGGTGTGGGCCTGAGCGGTTTCAGCGATGTCGAAGATGGCGCCGT
GCAGGGGCAGTTGTTCGGCCAGATGCCGCCGTTGGAGTGA

Upstream 100 bases:

>100_bases
CGTGTTCGCTTTGCCAATCCGTGGCGATGTCTCTCGACGCAAGGGGTGAGACGGCGCTGGCTTATCATGGGCGCAGACCT
GCGACAGAGAACCCCGCTTG

Downstream 100 bases:

>100_bases
GCGGCGCGGGCTGCATTGCGTCTCGCATGCGGCGATGACTGCATCTAACGCAGGTGGCGAGCAATCCACGGTGCTTGGCA
GTGACACGCGCTGAATCTTG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVRAERLCPDAIFVPPDFARYKA
VSRQVREIFHRHTDLVEPLSLDEAYLDVTHAKTGMQLATEVAQLIRTQIREETQLTASAGIAPNKFLAKIASDWRKPDGQ
FVIAPSRVDAFLLPLKVNRIPGVGKVMDGKLAALGIVTVADLRQRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQEVQ
SVSSEDTFSEDLALDALDPHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSYTPEQPPTSQEALAQIALALTRR
VELPTQTRYRLVGVGLSGFSDVEDGAVQGQLFGQMPPLE

Sequences:

>Translated_359_residues
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVRAERLCPDAIFVPPDFARYKA
VSRQVREIFHRHTDLVEPLSLDEAYLDVTHAKTGMQLATEVAQLIRTQIREETQLTASAGIAPNKFLAKIASDWRKPDGQ
FVIAPSRVDAFLLPLKVNRIPGVGKVMDGKLAALGIVTVADLRQRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQEVQ
SVSSEDTFSEDLALDALDPHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSYTPEQPPTSQEALAQIALALTRR
VELPTQTRYRLVGVGLSGFSDVEDGAVQGQLFGQMPPLE
>Mature_359_residues
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVRAERLCPDAIFVPPDFARYKA
VSRQVREIFHRHTDLVEPLSLDEAYLDVTHAKTGMQLATEVAQLIRTQIREETQLTASAGIAPNKFLAKIASDWRKPDGQ
FVIAPSRVDAFLLPLKVNRIPGVGKVMDGKLAALGIVTVADLRQRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQEVQ
SVSSEDTFSEDLALDALDPHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSYTPEQPPTSQEALAQIALALTRR
VELPTQTRYRLVGVGLSGFSDVEDGAVQGQLFGQMPPLE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=380, Percent_Identity=31.5789473684211, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI7706681, Length=381, Percent_Identity=31.496062992126, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI154350220, Length=357, Percent_Identity=29.1316526610644, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI7705344, Length=106, Percent_Identity=51.8867924528302, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI5729982, Length=331, Percent_Identity=29.0030211480363, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1786425, Length=253, Percent_Identity=52.5691699604743, Blast_Score=251, Evalue=4e-68,
Organism=Escherichia coli, GI1787432, Length=380, Percent_Identity=28.4210526315789, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193205700, Length=411, Percent_Identity=32.6034063260341, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17537959, Length=239, Percent_Identity=32.6359832635983, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=356, Percent_Identity=30.8988764044944, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115534089, Length=345, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324921, Length=249, Percent_Identity=26.9076305220884, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19923006, Length=429, Percent_Identity=24.9417249417249, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=28.6219081272085, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=28.6219081272085, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=35.2941176470588, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39964; Mature: 39964

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVR
CCCEEEECHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AERLCPDAIFVPPDFARYKAVSRQVREIFHRHTDLVEPLSLDEAYLDVTHAKTGMQLATE
HHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
VAQLIRTQIREETQLTASAGIAPNKFLAKIASDWRKPDGQFVIAPSRVDAFLLPLKVNRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEECCC
PGVGKVMDGKLAALGIVTVADLRQRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQEVQ
CCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
SVSSEDTFSEDLALDALDPHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSYTP
HCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCC
EQPPTSQEALAQIALALTRRVELPTQTRYRLVGVGLSGFSDVEDGAVQGQLFGQMPPLE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVR
CCCEEEECHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AERLCPDAIFVPPDFARYKAVSRQVREIFHRHTDLVEPLSLDEAYLDVTHAKTGMQLATE
HHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
VAQLIRTQIREETQLTASAGIAPNKFLAKIASDWRKPDGQFVIAPSRVDAFLLPLKVNRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEECCC
PGVGKVMDGKLAALGIVTVADLRQRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQEVQ
CCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
SVSSEDTFSEDLALDALDPHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSYTP
HCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCC
EQPPTSQEALAQIALALTRRVELPTQTRYRLVGVGLSGFSDVEDGAVQGQLFGQMPPLE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]