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The map label for this gene is gph [C]

Identifier: 78049295

GI number: 78049295

Start: 4319591

End: 4320241

Strand: Reverse

Name: gph [C]

Synonym: XCV3739

Alternate gene names: 78049295

Gene position: 4320241-4319591 (Counterclockwise)

Preceding gene: 78049296

Following gene: 78049292

Centisome position: 83.43

GC content: 64.67

Gene sequence:

>651_bases
ATGTTTCCGTATCCGCTGGTGATCTTCGACCTGGATGGCACGCTGGTGGACAGCGCACCCAATATCGCCGAGGCTCTCAA
CGGCACATTGCAGGAGCTGGGGCTACAGCAGTTCAGCCAAGCCACGATCCGCAGCTGGATCGGCGAAGGCGTCAAGGTAT
TGCTTGCCACCGCATTGCGCGAAGCCGGCAGCACGCGCGATGCCGATGCCGAAATGCCGGTGATGATGCGCCATTACGAG
GCGAGCCTGCTGCACGACCCGCAGTTGTACCCGGGCGTTGCCGAGGCGCTGGCCGGCCTGCGCGATGCGGGCGCCACGCT
GGCCTTGTGCACCAACAAGCCTGCGCGTTTTATCGCGCCGTTGCTGGAGCATCTGGGTATCGCCGCGCATTTCAGCCGTG
TGCTCGGGGGCGATTCGTTGCCACAGCGCAAGCCCGACCCGGCACCGCTGCTGCAGCTTGCCAGTCACTTTCAACGCAGC
CCGCAACAGTGTTTGATGGTTGGCGATTCGGCCACCGATGCCGCCGCCGCAAACGCCGCGAACATGCCGCTGGCGATGGT
GCGTTACGGCTACCTGCGCGGTTTCGATGTGCAGCGCGCCGGTGCCGTGGCCATCGTCGACGACATGCGTGAACTGCTCG
CGTTGCGCTGA

Upstream 100 bases:

>100_bases
ATCTAACGCAGGTGGCGAGCAATCCACGGTGCTTGGCAGTGACACGCGCTGAATCTTGCACTGCGTACACTGCGGCTCTC
CCACGCACGAGGCCGTCCGA

Downstream 100 bases:

>100_bases
CCTGCGCGCGCACCACGGATCGACCGATGCGGCGGCGTGCGTTACGGCCGCAGGCCCAAGCTCGGGCGTCTGCGCTGAAG
CGGGAGATTGTGCAACAGCG

Product: putative phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MFPYPLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSQATIRSWIGEGVKVLLATALREAGSTRDADAEMPVMMRHYE
ASLLHDPQLYPGVAEALAGLRDAGATLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKPDPAPLLQLASHFQRS
PQQCLMVGDSATDAAAANAANMPLAMVRYGYLRGFDVQRAGAVAIVDDMRELLALR

Sequences:

>Translated_216_residues
MFPYPLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSQATIRSWIGEGVKVLLATALREAGSTRDADAEMPVMMRHYE
ASLLHDPQLYPGVAEALAGLRDAGATLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKPDPAPLLQLASHFQRS
PQQCLMVGDSATDAAAANAANMPLAMVRYGYLRGFDVQRAGAVAIVDDMRELLALR
>Mature_216_residues
MFPYPLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSQATIRSWIGEGVKVLLATALREAGSTRDADAEMPVMMRHYE
ASLLHDPQLYPGVAEALAGLRDAGATLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKPDPAPLLQLASHFQRS
PQQCLMVGDSATDAAAANAANMPLAMVRYGYLRGFDVQRAGAVAIVDDMRELLALR

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=227, Percent_Identity=39.647577092511, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23175; Mature: 23175

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPYPLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSQATIRSWIGEGVKVLLATALR
CCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGSTRDADAEMPVMMRHYEASLLHDPQLYPGVAEALAGLRDAGATLALCTNKPARFIAP
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHH
LLEHLGIAAHFSRVLGGDSLPQRKPDPAPLLQLASHFQRSPQQCLMVGDSATDAAAANAA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHEEECCCCCHHHHCCCC
NMPLAMVRYGYLRGFDVQRAGAVAIVDDMRELLALR
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFPYPLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSQATIRSWIGEGVKVLLATALR
CCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGSTRDADAEMPVMMRHYEASLLHDPQLYPGVAEALAGLRDAGATLALCTNKPARFIAP
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHH
LLEHLGIAAHFSRVLGGDSLPQRKPDPAPLLQLASHFQRSPQQCLMVGDSATDAAAANAA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHEEECCCCCHHHHCCCC
NMPLAMVRYGYLRGFDVQRAGAVAIVDDMRELLALR
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA