Click here to switch to the map view.

The map label for this gene is fhuE [H]

Identifier: 78049045

GI number: 78049045

Start: 3993333

End: 3995516

Strand: Reverse

Name: fhuE [H]

Synonym: XCV3489

Alternate gene names: 78049045

Gene position: 3995516-3993333 (Counterclockwise)

Preceding gene: 78049046

Following gene: 78049044

Centisome position: 77.16

GC content: 62.73

Gene sequence:

>2184_bases
ATGATCCGTAGTACCGAAATGCGTCTTATTTCTGTGGGCGCACGCCGCCACGCCCTGCCCCGCGCACTGTTCGCTGCGCT
GTGTACGCTGGCCGCCGGCCAGGTCTTGGCAGAAGCGCCCACCGCCGATGCCGACGTCACCACGCTGGACCGGATGACCG
TGCAGGGTGAGCAGGCCAAGGGCTATACGGTGGAGAAAACCTCTGCCGGGACGCGGATGAACCTGGCGCTGCGCGAGATT
CCGCAGTCGGTCACCGTGATCACCCGCGAGCGCATGGATGACCAGAACCTGCAGAGCATCACCGACGTGCTCAACAACGT
CACCGGTATCTCGGCTTCGCAGAATGACAGCGAACGGTTGGACTTCTATGCGCGCGGCTTCTATATCGATAACTACCAAT
TCGATGGCATCCCGGCCTACATGGAGCAGGCGTGGAGCTACGGCGATTCGGCACTGGATGTAGCGCTGTACGACCGCGTG
GAAGTGGTGCGCGGCGCAACCGGTTTATTGACCGGCTCGGGTAATCCGTCGGCCTCGATCAATCTGGTACGCAAGCATGC
GCTCAGCCGCGACTTCACCGGCACCGTGTCGGTGGGCGGCGGGGACTTCAACAAGACCCGCAGCGTGGCCGATCTCACCG
TGCCGCTGAGTCCCGAAGGCACCGTGCGCGCACGCGTGGTGGGCGTGTATCAGGACGGCGAATCGGACATGGATCGCTAC
AGCCTGCGCAAGAAGATCGGCTCGGCCATCATCGATGCCGACCTCACCGACAGCACGCTGTTGAGCGTGGGCTATGAGTA
CCAGAAAAAGGAATCGGACGATGTCACCTGGGGCGGCTTCCCGCTGTTCTACAGCGATGGCACGCGTACCGACTACAAGC
GCTCGTTCAATCCGGCGGCCGACTGGACGTTCTGGGACACGCGCCTGCAGCGCACCTTCGCCAGCCTGCAACAGAGCTTC
GACAACGGCTGGACCCTCAAGGCCAATGTGAGCCACGAAAACACCGAAGCGACGAACCACCTGTTCTATCCGTTCTACAC
CATCTTCGGCTTCGACCGCACCACCGGCGGTGGGGTGGTGCCGTATTCGGGCAACTACCAGACCGAGCGCAAGGCCGACG
GCGCCGACGTGTATGCCCAGGGCCCGTTCCAGCTGTTCGGCCGCGAACATCAACTGGTCGCCGGCGCCAGCTACAACCGG
CGCGAGTACGTCAATAACGGTACCTTCGACTTCCCCGCACCCCTGGACAGCTACCTGGGCTGGAATGGCGCGTATCCGGA
GCCCAACTGGAGCCCGCGCACGGTGCAGAGCGATGGCACCATCAAGCAGAAGGCCGCCTACGTGGCCGCACGCTTCTCGC
TGGCCGATCCACTGACGTTGCTGGTGGGCGCGCGCTATACCGATTGGCAGATTGACGGCCGTAACGCCGATGCGACGCAG
GGGCTGGTGCCGTTCTCCGACACCCAGACCGAAGTCACTCCATACGCCGGGCTGGTCTACGACATCGACGATGTCTGGTC
GACCTATGTCAGCTACACCGAGATCTTCAACCCGCAGACCTTGCGCGATGCCAATGGCGGCTACCTGGATCCGTTGAGCG
GCAAGGGCTACGAAGCCGGCGTCAAGGCGGCCTGGTTCGACGACCAGCTCAATGCCTCGCTGGCCCTGTTCCGCATCGAG
CAGGACAATCTAGGTGTAGCGACGAGCACGCTGGTGCCGGGCAGCAGCGATTTTGCTTACGTCGCTGCCAGTGGTGTGGT
CAGCGAAGGCTTCGATTTCGAACTTTCCGGCCGCCTGACCCAGGGCTGGAACGCGACCTTGGGCGCCTCGCACTACACCG
CACGCGACGACAGCGGTGCCTCGATCAACACGCAACTGCCGCGCACCACCATCAAGCTGTTCAGTAGCTACACCCCACAG
GGCGCGTGGAGCGACCTGACCGTGGGCGGTGGCGTCAACTGGCAGAACCGTTCGTACTATGTGGACCCGGTGTATGGCAC
CTTCCAGCAGAGCCCGTACGCAGTGGTCAGCGCGTTTGCGCGCTATCGCCTGTCGCCGCAGTTTTCGGTGCAGCTCAATA
TCGACAACCTGCTCGACAAGCGTTACTACGCGCAGTTCAACAATGGCTATGGTGCGTGGGGCGCCTCGCGCAACGGCATG
CTGACCTTCAACTACACGTTCTGA

Upstream 100 bases:

>100_bases
ATGCGCTGCCAATGGTATGGCGCACCGTTCCTCCCCCTTGTTGCCGGCGCTGCGCCTATGCGGTGCGTGCGGCCCGATCC
GTCTGCGTTGGAGTCACCCG

Downstream 100 bases:

>100_bases
TCTGAAGCGACATCGGGCGTCTGCAACGCTCGCTGCGATTGCGCCATGGCACGGGCATCTTGCGAAAGATGCTTGTGCTT
TTTGGTGTTCCGAGTTTCAG

Product: TonB-dependent outer membrane receptor

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 727; Mature: 727

Protein sequence:

>727_residues
MIRSTEMRLISVGARRHALPRALFAALCTLAAGQVLAEAPTADADVTTLDRMTVQGEQAKGYTVEKTSAGTRMNLALREI
PQSVTVITRERMDDQNLQSITDVLNNVTGISASQNDSERLDFYARGFYIDNYQFDGIPAYMEQAWSYGDSALDVALYDRV
EVVRGATGLLTGSGNPSASINLVRKHALSRDFTGTVSVGGGDFNKTRSVADLTVPLSPEGTVRARVVGVYQDGESDMDRY
SLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFYSDGTRTDYKRSFNPAADWTFWDTRLQRTFASLQQSF
DNGWTLKANVSHENTEATNHLFYPFYTIFGFDRTTGGGVVPYSGNYQTERKADGADVYAQGPFQLFGREHQLVAGASYNR
REYVNNGTFDFPAPLDSYLGWNGAYPEPNWSPRTVQSDGTIKQKAAYVAARFSLADPLTLLVGARYTDWQIDGRNADATQ
GLVPFSDTQTEVTPYAGLVYDIDDVWSTYVSYTEIFNPQTLRDANGGYLDPLSGKGYEAGVKAAWFDDQLNASLALFRIE
QDNLGVATSTLVPGSSDFAYVAASGVVSEGFDFELSGRLTQGWNATLGASHYTARDDSGASINTQLPRTTIKLFSSYTPQ
GAWSDLTVGGGVNWQNRSYYVDPVYGTFQQSPYAVVSAFARYRLSPQFSVQLNIDNLLDKRYYAQFNNGYGAWGASRNGM
LTFNYTF

Sequences:

>Translated_727_residues
MIRSTEMRLISVGARRHALPRALFAALCTLAAGQVLAEAPTADADVTTLDRMTVQGEQAKGYTVEKTSAGTRMNLALREI
PQSVTVITRERMDDQNLQSITDVLNNVTGISASQNDSERLDFYARGFYIDNYQFDGIPAYMEQAWSYGDSALDVALYDRV
EVVRGATGLLTGSGNPSASINLVRKHALSRDFTGTVSVGGGDFNKTRSVADLTVPLSPEGTVRARVVGVYQDGESDMDRY
SLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFYSDGTRTDYKRSFNPAADWTFWDTRLQRTFASLQQSF
DNGWTLKANVSHENTEATNHLFYPFYTIFGFDRTTGGGVVPYSGNYQTERKADGADVYAQGPFQLFGREHQLVAGASYNR
REYVNNGTFDFPAPLDSYLGWNGAYPEPNWSPRTVQSDGTIKQKAAYVAARFSLADPLTLLVGARYTDWQIDGRNADATQ
GLVPFSDTQTEVTPYAGLVYDIDDVWSTYVSYTEIFNPQTLRDANGGYLDPLSGKGYEAGVKAAWFDDQLNASLALFRIE
QDNLGVATSTLVPGSSDFAYVAASGVVSEGFDFELSGRLTQGWNATLGASHYTARDDSGASINTQLPRTTIKLFSSYTPQ
GAWSDLTVGGGVNWQNRSYYVDPVYGTFQQSPYAVVSAFARYRLSPQFSVQLNIDNLLDKRYYAQFNNGYGAWGASRNGM
LTFNYTF
>Mature_727_residues
MIRSTEMRLISVGARRHALPRALFAALCTLAAGQVLAEAPTADADVTTLDRMTVQGEQAKGYTVEKTSAGTRMNLALREI
PQSVTVITRERMDDQNLQSITDVLNNVTGISASQNDSERLDFYARGFYIDNYQFDGIPAYMEQAWSYGDSALDVALYDRV
EVVRGATGLLTGSGNPSASINLVRKHALSRDFTGTVSVGGGDFNKTRSVADLTVPLSPEGTVRARVVGVYQDGESDMDRY
SLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFYSDGTRTDYKRSFNPAADWTFWDTRLQRTFASLQQSF
DNGWTLKANVSHENTEATNHLFYPFYTIFGFDRTTGGGVVPYSGNYQTERKADGADVYAQGPFQLFGREHQLVAGASYNR
REYVNNGTFDFPAPLDSYLGWNGAYPEPNWSPRTVQSDGTIKQKAAYVAARFSLADPLTLLVGARYTDWQIDGRNADATQ
GLVPFSDTQTEVTPYAGLVYDIDDVWSTYVSYTEIFNPQTLRDANGGYLDPLSGKGYEAGVKAAWFDDQLNASLALFRIE
QDNLGVATSTLVPGSSDFAYVAASGVVSEGFDFELSGRLTQGWNATLGASHYTARDDSGASINTQLPRTTIKLFSSYTPQ
GAWSDLTVGGGVNWQNRSYYVDPVYGTFQQSPYAVVSAFARYRLSPQFSVQLNIDNLLDKRYYAQFNNGYGAWGASRNGM
LTFNYTF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=727, Percent_Identity=44.4291609353508, Blast_Score=601, Evalue=1e-173,
Organism=Escherichia coli, GI1786344, Length=763, Percent_Identity=22.6736566186107, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80165; Mature: 80165

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00617 RECF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSTEMRLISVGARRHALPRALFAALCTLAAGQVLAEAPTADADVTTLDRMTVQGEQAK
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHEEECCCCCC
GYTVEKTSAGTRMNLALREIPQSVTVITRERMDDQNLQSITDVLNNVTGISASQNDSERL
CEEEEECCCCCEEEHHHHHCCCHHEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHE
DFYARGFYIDNYQFDGIPAYMEQAWSYGDSALDVALYDRVEVVRGATGLLTGSGNPSASI
EEEEEEEEEECEEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCCCH
NLVRKHALSRDFTGTVSVGGGDFNKTRSVADLTVPLSPEGTVRARVVGVYQDGESDMDRY
HHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCCHHHHH
SLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFYSDGTRTDYKRSFNPAA
HHHHHHHHHEEECCCCCCHHHHCCCHHHCCCCCCCEECCEEEEECCCCCCCHHHCCCCCC
DWTFWDTRLQRTFASLQQSFDNGWTLKANVSHENTEATNHLFYPFYTIFGFDRTTGGGVV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCEE
PYSGNYQTERKADGADVYAQGPFQLFGREHQLVAGASYNRREYVNNGTFDFPAPLDSYLG
CCCCCCCCCCCCCCCCEEECCCHHHCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHCC
WNGAYPEPNWSPRTVQSDGTIKQKAAYVAARFSLADPLTLLVGARYTDWQIDGRNADATQ
CCCCCCCCCCCCCEECCCCCHHHHHHHHHEECCCCCCHHHHHCCCCCCEEECCCCCCCCC
GLVPFSDTQTEVTPYAGLVYDIDDVWSTYVSYTEIFNPQTLRDANGGYLDPLSGKGYEAG
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCCCCC
VKAAWFDDQLNASLALFRIEQDNLGVATSTLVPGSSDFAYVAASGVVSEGFDFELSGRLT
CEEEEECCCCCCEEEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEECCCEE
QGWNATLGASHYTARDDSGASINTQLPRTTIKLFSSYTPQGAWSDLTVGGGVNWQNRSYY
CCCCCCCCCCCEECCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEE
VDPVYGTFQQSPYAVVSAFARYRLSPQFSVQLNIDNLLDKRYYAQFNNGYGAWGASRNGM
ECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHEEECCCEEECCCCCCCE
LTFNYTF
EEEEECC
>Mature Secondary Structure
MIRSTEMRLISVGARRHALPRALFAALCTLAAGQVLAEAPTADADVTTLDRMTVQGEQAK
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHEEECCCCCC
GYTVEKTSAGTRMNLALREIPQSVTVITRERMDDQNLQSITDVLNNVTGISASQNDSERL
CEEEEECCCCCEEEHHHHHCCCHHEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHE
DFYARGFYIDNYQFDGIPAYMEQAWSYGDSALDVALYDRVEVVRGATGLLTGSGNPSASI
EEEEEEEEEECEEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCCCH
NLVRKHALSRDFTGTVSVGGGDFNKTRSVADLTVPLSPEGTVRARVVGVYQDGESDMDRY
HHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCCHHHHH
SLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFYSDGTRTDYKRSFNPAA
HHHHHHHHHEEECCCCCCHHHHCCCHHHCCCCCCCEECCEEEEECCCCCCCHHHCCCCCC
DWTFWDTRLQRTFASLQQSFDNGWTLKANVSHENTEATNHLFYPFYTIFGFDRTTGGGVV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCEE
PYSGNYQTERKADGADVYAQGPFQLFGREHQLVAGASYNRREYVNNGTFDFPAPLDSYLG
CCCCCCCCCCCCCCCCEEECCCHHHCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHCC
WNGAYPEPNWSPRTVQSDGTIKQKAAYVAARFSLADPLTLLVGARYTDWQIDGRNADATQ
CCCCCCCCCCCCCEECCCCCHHHHHHHHHEECCCCCCHHHHHCCCCCCEEECCCCCCCCC
GLVPFSDTQTEVTPYAGLVYDIDDVWSTYVSYTEIFNPQTLRDANGGYLDPLSGKGYEAG
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCCCCC
VKAAWFDDQLNASLALFRIEQDNLGVATSTLVPGSSDFAYVAASGVVSEGFDFELSGRLT
CEEEEECCCCCCEEEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEECCCEE
QGWNATLGASHYTARDDSGASINTQLPRTTIKLFSSYTPQGAWSDLTVGGGVNWQNRSYY
CCCCCCCCCCCEECCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEE
VDPVYGTFQQSPYAVVSAFARYRLSPQFSVQLNIDNLLDKRYYAQFNNGYGAWGASRNGM
ECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHEEECCCEEECCCCCCCE
LTFNYTF
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]